SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1wlk'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2EIM_J_CHDJ60_0 (CYTOCHROME C OXIDASE POLYPEPTIDE VIIA-HEART)	1wlk	FMN-BINDING PROTEIN (Desulfovibrio vulgaris)	4 / 5	ARG A 86 MET A 66 THR A 67 LEU A 68	None	1.09A	2eimJ-1wlkA: undetectable	2eimJ-1wlkA: 22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2WLJ_A_SPMA1303_1 (POTASSIUM CHANNEL)	1wlk	FMN-BINDING PROTEIN (Desulfovibrio vulgaris)	3 / 3	ARG A 43 ARG A 92 PRO A 96	None	1.09A	2wljA-1wlkA: undetectable	2wljA-1wlkA: 18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AG1_J_CHDJ60_0 (CYTOCHROME C OXIDASE POLYPEPTIDE 7A1)	1wlk	FMN-BINDING PROTEIN (Desulfovibrio vulgaris)	4 / 5	ARG A 86 MET A 66 THR A 67 LEU A 68	None	1.28A	3ag1J-1wlkA: undetectable	3ag1J-1wlkA: 22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5I3C_C_AC2C301_1 (PURINE NUCLEOSIDE PHOSPHORYLASE DEOD-TYPE)	1wlk	FMN-BINDING PROTEIN (Desulfovibrio vulgaris)	5 / 11	GLY A 87 ALA A 19 VAL A 64 SER A 117 ILE A 113	None	1.14A	5i3cC-1wlkA: undetectable	5i3cC-1wlkA: 22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5WAU_J_CHDJ101_1 (CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	1wlk	FMN-BINDING PROTEIN (Desulfovibrio vulgaris)	4 / 5	ARG A 86 MET A 66 THR A 67 LEU A 68	None	1.23A	5wauJ-1wlkA: undetectable	5wauJ-1wlkA: 22.41

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2EIM_J_CHDJ60_0","CYTOCHROME C OXIDASE POLYPEPTIDE VIIA-HEART","1wlk","FMN-BINDING PROTEIN","Desulfovibrio vulgaris",4,"ARG A  86;MET A  66;THR A  67;LEU A  68","None","1.09A","2eimJ-1wlkA:undetectable","2eimJ-1wlkA:22.41"],["2WLJ_A_SPMA1303_1","POTASSIUM CHANNEL","1wlk","FMN-BINDING PROTEIN","Desulfovibrio vulgaris",3,"ARG A  43;ARG A  92;PRO A  96","None","1.09A","2wljA-1wlkA:undetectable","2wljA-1wlkA:18.52"],["3AG1_J_CHDJ60_0","CYTOCHROME C OXIDASE POLYPEPTIDE 7A1","1wlk","FMN-BINDING PROTEIN","Desulfovibrio vulgaris",4,"ARG A  86;MET A  66;THR A  67;LEU A  68","None","1.28A","3ag1J-1wlkA:undetectable","3ag1J-1wlkA:22.41"],["5I3C_C_AC2C301_1","PURINE NUCLEOSIDE PHOSPHORYLASE DEOD-TYPE","1wlk","FMN-BINDING PROTEIN","Desulfovibrio vulgaris",5,"GLY A  87;ALA A  19;VAL A  64;SER A 117;ILE A 113","None","1.14A","5i3cC-1wlkA:undetectable","5i3cC-1wlkA:22.08"],["5WAU_J_CHDJ101_1","CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","1wlk","FMN-BINDING PROTEIN","Desulfovibrio vulgaris",4,"ARG A  86;MET A  66;THR A  67;LEU A  68","None","1.23A","5wauJ-1wlkA:undetectable","5wauJ-1wlkA:22.41"]]