SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1wlm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1QKU_A_ESTA600_1 (ESTRADIOL RECEPTOR)	1wlm	PROTEIN CGI-38 (Mus musculus)	5 / 10	ALA A 52 LEU A 89 LEU A 86 MET A 37 ILE A 77	None	1.26A	1qkuA-1wlmA: undetectable	1qkuA-1wlmA: 21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2KOT_B_ANWB99_0 (PROTEIN S100-A13)	1wlm	PROTEIN CGI-38 (Mus musculus)	4 / 8	VAL A 120 THR A 121 LYS A 47 ASP A 48	None	1.10A	2kotB-1wlmA: 4.3	2kotB-1wlmA: 25.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3R75_A_BEZA701_0 (ANTHRANILATE/PARA-AM INOBENZOATE SYNTHASES COMPONENT I)	1wlm	PROTEIN CGI-38 (Mus musculus)	5 / 12	GLU A 144 SER A 141 GLY A 140 THR A 139 HIS A 142	None	1.16A	3r75A-1wlmA: undetectable	3r75A-1wlmA: 12.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3R75_B_BEZB701_0 (ANTHRANILATE/PARA-AM INOBENZOATE SYNTHASES COMPONENT I)	1wlm	PROTEIN CGI-38 (Mus musculus)	5 / 12	GLU A 144 SER A 141 GLY A 140 THR A 139 HIS A 142	None	1.19A	3r75B-1wlmA: undetectable	3r75B-1wlmA: 12.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3R76_A_BEZA701_0 (ANTHRANILATE/PARA-AM INOBENZOATE SYNTHASES COMPONENT I)	1wlm	PROTEIN CGI-38 (Mus musculus)	5 / 11	GLU A 144 SER A 141 GLY A 140 THR A 139 HIS A 142	None	1.15A	3r76A-1wlmA: undetectable	3r76A-1wlmA: 12.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3R76_B_BEZB701_0 (ANTHRANILATE/PARA-AM INOBENZOATE SYNTHASES COMPONENT I)	1wlm	PROTEIN CGI-38 (Mus musculus)	5 / 11	GLU A 144 SER A 141 GLY A 140 THR A 139 HIS A 142	None	1.16A	3r76B-1wlmA: undetectable	3r76B-1wlmA: 12.86

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1QKU_A_ESTA600_1","ESTRADIOL RECEPTOR","1wlm","PROTEIN CGI-38","Mus musculus",5,"ALA A  52;LEU A  89;LEU A  86;MET A  37;ILE A  77","None","1.26A","1qkuA-1wlmA:undetectable","1qkuA-1wlmA:21.74"],["2KOT_B_ANWB99_0","PROTEIN S100-A13","1wlm","PROTEIN CGI-38","Mus musculus",4,"VAL A 120;THR A 121;LYS A  47;ASP A  48","None","1.10A","2kotB-1wlmA:4.3","2kotB-1wlmA:25.17"],["3R75_A_BEZA701_0","ANTHRANILATE\/PARA-AMINOBENZOATE SYNTHASES COMPONENT I","1wlm","PROTEIN CGI-38","Mus musculus",5,"GLU A 144;SER A 141;GLY A 140;THR A 139;HIS A 142","None","1.16A","3r75A-1wlmA:undetectable","3r75A-1wlmA:12.86"],["3R75_B_BEZB701_0","ANTHRANILATE\/PARA-AMINOBENZOATE SYNTHASES COMPONENT I","1wlm","PROTEIN CGI-38","Mus musculus",5,"GLU A 144;SER A 141;GLY A 140;THR A 139;HIS A 142","None","1.19A","3r75B-1wlmA:undetectable","3r75B-1wlmA:12.86"],["3R76_A_BEZA701_0","ANTHRANILATE\/PARA-AMINOBENZOATE SYNTHASES COMPONENT I","1wlm","PROTEIN CGI-38","Mus musculus",5,"GLU A 144;SER A 141;GLY A 140;THR A 139;HIS A 142","None","1.15A","3r76A-1wlmA:undetectable","3r76A-1wlmA:12.86"],["3R76_B_BEZB701_0","ANTHRANILATE\/PARA-AMINOBENZOATE SYNTHASES COMPONENT I","1wlm","PROTEIN CGI-38","Mus musculus",5,"GLU A 144;SER A 141;GLY A 140;THR A 139;HIS A 142","None","1.16A","3r76B-1wlmA:undetectable","3r76B-1wlmA:12.86"]]