SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1wln'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HDN_B_TACB1888_1
(ELONGATION FACTOR
EF-TU)		 1wln AFADIN
(Mus
musculus) 		4 / 5 SER A  24
ASP A  26
PRO A  28
SER A  18
 None
 1.45A 2hdnA-1wlnA:
undetectable
2hdnB-1wlnA:
undetectable
2hdnD-1wlnA:
undetectable		 2hdnA-1wlnA:
12.50
2hdnB-1wlnA:
16.12
2hdnD-1wlnA:
16.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HDN_D_TACD2888_1
(ELONGATION FACTOR
EF-TU)		 1wln AFADIN
(Mus
musculus) 		4 / 5 SER A  18
SER A  24
ASP A  26
PRO A  28
 None
 1.45A 2hdnB-1wlnA:
undetectable
2hdnC-1wlnA:
undetectable
2hdnD-1wlnA:
undetectable		 2hdnB-1wlnA:
16.12
2hdnC-1wlnA:
12.50
2hdnD-1wlnA:
16.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A35_A_RBFA191_1
(LUMAZINE PROTEIN)		 1wln AFADIN
(Mus
musculus) 		5 / 12 VAL A  37
CYH A  62
LEU A  64
THR A  65
THR A  82
 None
 1.20A 3a35A-1wlnA:
undetectable		 3a35A-1wlnA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A35_B_RBFB191_1
(LUMAZINE PROTEIN)		 1wln AFADIN
(Mus
musculus) 		5 / 12 VAL A  37
CYH A  62
LEU A  64
THR A  65
THR A  82
 None
 1.19A 3a35B-1wlnA:
undetectable		 3a35B-1wlnA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A3B_A_RBFA191_1
(LUMAZINE PROTEIN)		 1wln AFADIN
(Mus
musculus) 		5 / 12 VAL A  37
CYH A  62
LEU A  64
THR A  65
THR A  82
 None
 1.21A 3a3bA-1wlnA:
undetectable		 3a3bA-1wlnA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TM4_A_SAMA401_1
(TRNA (GUANINE
N2-)-METHYLTRANSFERA
SE TRM14)		 1wln AFADIN
(Mus
musculus) 		4 / 5 HIS A 107
SER A 106
GLU A  16
ASP A  26
 None
 1.43A 3tm4A-1wlnA:
undetectable		 3tm4A-1wlnA:
18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TM4_B_SAMB401_1
(TRNA (GUANINE
N2-)-METHYLTRANSFERA
SE TRM14)		 1wln AFADIN
(Mus
musculus) 		4 / 5 HIS A 107
SER A 106
GLU A  16
ASP A  26
 None
 1.40A 3tm4B-1wlnA:
undetectable		 3tm4B-1wlnA:
18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_G_SAMG301_1
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))		 1wln AFADIN
(Mus
musculus) 		4 / 4 ASP A  26
HIS A 107
SER A 106
GLU A  16
 None
 1.37A 5hfjG-1wlnA:
0.0		 5hfjG-1wlnA:
15.38