SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1wlo'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CQP_A_803A311_1
(ANTIGEN CD11A (P180))		 1wlo SUFE PROTEIN
(Thermus
thermophilus) 		5 / 10 LEU A   6
VAL A   2
LEU A 116
GLU A 108
LEU A 107
 None
 1.20A 1cqpA-1wloA:
undetectable
1cqpB-1wloA:
undetectable		 1cqpA-1wloA:
20.74
1cqpB-1wloA:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DQY_C_CHDC3_0
(LIVER
CARBOXYLESTERASE 1)		 1wlo SUFE PROTEIN
(Thermus
thermophilus) 		4 / 6 LEU A 107
LEU A  10
PRO A  98
VAL A   2
 None
 1.21A 2dqyC-1wloA:
undetectable		 2dqyC-1wloA:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OD9_A_NCAA3721_0
(NAD-DEPENDENT
DEACETYLASE HST2)		 1wlo SUFE PROTEIN
(Thermus
thermophilus) 		3 / 3 PHE A  13
PHE A 110
PHE A 111
 None
 0.84A 2od9A-1wloA:
undetectable		 2od9A-1wloA:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQG_A_NCAA3721_0
(NAD-DEPENDENT
DEACETYLASE HST2)		 1wlo SUFE PROTEIN
(Thermus
thermophilus) 		3 / 3 PHE A  13
PHE A 110
PHE A 111
 None
 0.84A 2qqgA-1wloA:
undetectable		 2qqgA-1wloA:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3APV_B_TP0B190_1
(ALPHA-1-ACID
GLYCOPROTEIN 2)		 1wlo SUFE PROTEIN
(Thermus
thermophilus) 		5 / 12 PHE A  51
VAL A  53
PHE A 101
LEU A   6
ALA A  77
 None
 1.43A 3apvB-1wloA:
0.0		 3apvB-1wloA:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUF_B_SUEB1201_2
(NS3 PROTEASE, NS4A
PROTEIN)		 1wlo SUFE PROTEIN
(Thermus
thermophilus) 		3 / 3 TYR A 105
LEU A 114
ARG A 103
 None
 0.78A 3sufB-1wloA:
undetectable		 3sufB-1wloA:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGZ_A_CQAA302_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 1wlo SUFE PROTEIN
(Thermus
thermophilus) 		4 / 7 GLU A  87
GLU A  89
GLY A  80
ARG A  83
 None
 0.95A 4fgzA-1wloA:
undetectable		 4fgzA-1wloA:
17.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HYT_A_OBNA1104_1
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 1wlo SUFE PROTEIN
(Thermus
thermophilus) 		5 / 12 LEU A 119
GLU A  89
GLY A  80
ALA A  77
LEU A  10
 None
 1.08A 4hytA-1wloA:
undetectable		 4hytA-1wloA:
9.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HYT_C_OBNC2004_1
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 1wlo SUFE PROTEIN
(Thermus
thermophilus) 		5 / 12 LEU A 119
GLU A  89
GLY A  80
ALA A  77
LEU A  10
 None
 1.10A 4hytC-1wloA:
undetectable		 4hytC-1wloA:
9.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JLT_A_8PRA505_1
(CYTOCHROME P450 2B4)		 1wlo SUFE PROTEIN
(Thermus
thermophilus) 		4 / 8 ALA A  77
VAL A  68
PRO A  69
VAL A  53
 None
 0.81A 4jltA-1wloA:
undetectable		 4jltA-1wloA:
14.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODO_B_FK5B203_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD)		 1wlo SUFE PROTEIN
(Thermus
thermophilus) 		5 / 10 LEU A 107
LEU A 123
LEU A  86
LEU A   6
LEU A  25
 None
 1.10A 4odoB-1wloA:
undetectable		 4odoB-1wloA:
24.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RET_A_DGXA1107_1
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 1wlo SUFE PROTEIN
(Thermus
thermophilus) 		5 / 12 LEU A 119
GLU A  89
GLY A  80
ALA A  77
LEU A  10
 None
 1.17A 4retA-1wloA:
undetectable		 4retA-1wloA:
9.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RET_C_DGXC2005_1
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 1wlo SUFE PROTEIN
(Thermus
thermophilus) 		5 / 12 LEU A 119
GLU A  89
GLY A  80
ALA A  77
LEU A  10
 None
 1.17A 4retC-1wloA:
undetectable		 4retC-1wloA:
9.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X6Y_A_SAMA902_0
(MRNA CAPPING ENZYME
P5)		 1wlo SUFE PROTEIN
(Thermus
thermophilus) 		5 / 12 LEU A  10
GLY A  80
ALA A   9
VAL A  75
PHE A  51
 None
 1.22A 5x6yA-1wloA:
undetectable		 5x6yA-1wloA:
11.22