SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1wlp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1LQT_B_ACTB1873_0 (FPRA)	1wlp	NEUTROPHIL CYTOSOL FACTOR 1 (Homo sapiens)	3 / 3	ASP B 217 ASP B 221 LYS B 188	None	0.98A	1lqtB-1wlpB: undetectable	1lqtB-1wlpB: 14.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1LQU_B_ACTB1430_0 (FPRA)	1wlp	NEUTROPHIL CYTOSOL FACTOR 1 (Homo sapiens)	3 / 3	ASP B 217 ASP B 221 LYS B 188	None	0.98A	1lquB-1wlpB: undetectable	1lquB-1wlpB: 14.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2AVV_A_MK1A901_2 (POL POLYPROTEIN)	1wlp	NEUTROPHIL CYTOSOL FACTOR 1 (Homo sapiens)	3 / 3	ASP B 243 VAL B 265 PRO B 224	None	0.79A	2avvA-1wlpB: undetectable	2avvA-1wlpB: 22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5L5F_Y_BO2Y301_1 (PROTEASOME SUBUNIT BETA TYPE-8,PROTEASOME SUBUNIT BETA TYPE-5 PROTEASOME SUBUNIT BETA TYPE-6,PROTEASOME SUBUNIT BETA TYPE-1,PROTEASOME SUBUNIT BETA TYPE-6,PROTEASOME SUBUNIT BETA TYPE-1,PROTEASOME SUBUNIT BETA TYPE-6)	1wlp	NEUTROPHIL CYTOSOL FACTOR 1 (Homo sapiens)	4 / 8	SER B 191 SER B 277 ALA B 207 SER B 208	None	1.04A	5l5fY-1wlpB: undetectable 5l5fZ-1wlpB: undetectable	5l5fY-1wlpB: 22.56 5l5fZ-1wlpB: 22.27

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1LQT_B_ACTB1873_0","FPRA","1wlp","NEUTROPHIL CYTOSOL FACTOR 1","Homo sapiens",3,"ASP B 217;ASP B 221;LYS B 188","None","0.98A","1lqtB-1wlpB:undetectable","1lqtB-1wlpB:14.99"],["1LQU_B_ACTB1430_0","FPRA","1wlp","NEUTROPHIL CYTOSOL FACTOR 1","Homo sapiens",3,"ASP B 217;ASP B 221;LYS B 188","None","0.98A","1lquB-1wlpB:undetectable","1lquB-1wlpB:14.99"],["2AVV_A_MK1A901_2","POL POLYPROTEIN","1wlp","NEUTROPHIL CYTOSOL FACTOR 1","Homo sapiens",3,"ASP B 243;VAL B 265;PRO B 224","None","0.79A","2avvA-1wlpB:undetectable","2avvA-1wlpB:22.66"],["5L5F_Y_BO2Y301_1","PROTEASOME SUBUNIT BETA TYPE-8,PROTEASOME SUBUNIT BETA TYPE-5;PROTEASOME SUBUNIT BETA TYPE-6,PROTEASOME SUBUNIT BETA TYPE-1,PROTEASOME SUBUNIT BETA TYPE-6,PROTEASOME SUBUNIT BETA TYPE-1,PROTEASOME SUBUNIT BETA TYPE-6","1wlp","NEUTROPHIL CYTOSOL FACTOR 1","Homo sapiens",4,"SER B 191;SER B 277;ALA B 207;SER B 208","None","1.04A","5l5fY-1wlpB:undetectable;5l5fZ-1wlpB:undetectable","5l5fY-1wlpB:22.56;5l5fZ-1wlpB:22.27"]]