SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1wm6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1LII_A_ADNA699_2 (ADENOSINE KINASE)	1wm6	PHENYLACETIC ACID DEGRADATION PROTEIN PAAI (Thermus thermophilus)	4 / 4	SER A 55 LEU A 89 TYR A 96 GLY A 59	None	1.19A	1liiA-1wm6A: undetectable	1liiA-1wm6A: 17.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2UYQ_A_SAMA1311_0 (HYPOTHETICAL PROTEIN ML2640)	1wm6	PHENYLACETIC ACID DEGRADATION PROTEIN PAAI (Thermus thermophilus)	4 / 7	ALA A 38 GLY A 40 ASP A 30 ARG A 28	None	0.63A	2uyqA-1wm6A: undetectable	2uyqA-1wm6A: 18.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3JB3_A_SAMA1102_0 (STRUCTURAL PROTEIN VP3)	1wm6	PHENYLACETIC ACID DEGRADATION PROTEIN PAAI (Thermus thermophilus)	5 / 12	ALA A 45 ALA A 38 PHE A 71 ALA A 82 VAL A 100	None	1.07A	3jb3A-1wm6A: undetectable	3jb3A-1wm6A: 9.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6HD4_B_STIB602_1 (TYROSINE-PROTEIN KINASE ABL1)	1wm6	PHENYLACETIC ACID DEGRADATION PROTEIN PAAI (Thermus thermophilus)	4 / 6	LEU A 9 VAL A 114 PHE A 42 GLY A 25	None	0.99A	6hd4B-1wm6A: undetectable	6hd4B-1wm6A: 21.19

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1LII_A_ADNA699_2","ADENOSINE KINASE","1wm6","PHENYLACETIC ACID DEGRADATION PROTEIN PAAI","Thermus thermophilus",4,"SER A  55;LEU A  89;TYR A  96;GLY A  59","None","1.19A","1liiA-1wm6A:undetectable","1liiA-1wm6A:17.40"],["2UYQ_A_SAMA1311_0","HYPOTHETICAL PROTEIN ML2640","1wm6","PHENYLACETIC ACID DEGRADATION PROTEIN PAAI","Thermus thermophilus",4,"ALA A  38;GLY A  40;ASP A  30;ARG A  28","None","0.63A","2uyqA-1wm6A:undetectable","2uyqA-1wm6A:18.24"],["3JB3_A_SAMA1102_0","STRUCTURAL PROTEIN VP3","1wm6","PHENYLACETIC ACID DEGRADATION PROTEIN PAAI","Thermus thermophilus",5,"ALA A  45;ALA A  38;PHE A  71;ALA A  82;VAL A 100","None","1.07A","3jb3A-1wm6A:undetectable","3jb3A-1wm6A:9.02"],["6HD4_B_STIB602_1","TYROSINE-PROTEIN KINASE ABL1","1wm6","PHENYLACETIC ACID DEGRADATION PROTEIN PAAI","Thermus thermophilus",4,"LEU A   9;VAL A 114;PHE A  42;GLY A  25","None","0.99A","6hd4B-1wm6A:undetectable","6hd4B-1wm6A:21.19"]]