SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1wmi'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P6G_A_IZPA133_1
(FATTY ACID-BINDING
PROTEIN, ADIPOCYTE)		 1wmi HYPOTHETICAL PROTEIN
PHS013
(Pyrococcus
horikoshii) 		5 / 12 PHE A  43
ASP A  31
ILE A  79
VAL A  66
TYR A  64
 None
 1.38A 3p6gA-1wmiA:
undetectable		 3p6gA-1wmiA:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PYY_A_STIA3_2
(V-ABL ABELSON MURINE
LEUKEMIA VIRAL
ONCOGENE HOMOLOG 1
ISOFORM B VARIANT)		 1wmi HYPOTHETICAL PROTEIN
PHS013
(Pyrococcus
horikoshii) 		4 / 6 TYR A  35
VAL A  66
VAL A   5
ARG A  25
 None
 1.11A 3pyyA-1wmiA:
undetectable		 3pyyA-1wmiA:
12.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V81_C_NVPC901_1
(HIV-1 REVERSE
TRANSCRIPTASE P66
SUBUNIT)		 1wmi HYPOTHETICAL PROTEIN
PHS013
(Pyrococcus
horikoshii) 		4 / 8 LEU A  33
VAL A  45
VAL A  66
TYR A  57
 None
 0.95A 3v81C-1wmiA:
undetectable		 3v81C-1wmiA:
11.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PUO_C_NVPC901_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)		 1wmi HYPOTHETICAL PROTEIN
PHS013
(Pyrococcus
horikoshii) 		4 / 8 LEU A  33
VAL A  45
VAL A  66
TYR A  57
 None
 0.95A 4puoC-1wmiA:
undetectable		 4puoC-1wmiA:
11.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWD_A_NVPA901_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)		 1wmi HYPOTHETICAL PROTEIN
PHS013
(Pyrococcus
horikoshii) 		4 / 8 LEU A  33
VAL A  45
VAL A  66
TYR A  57
 None
 0.90A 4pwdA-1wmiA:
undetectable		 4pwdA-1wmiA:
11.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWD_C_NVPC901_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)		 1wmi HYPOTHETICAL PROTEIN
PHS013
(Pyrococcus
horikoshii) 		4 / 8 LEU A  33
VAL A  45
VAL A  66
TYR A  57
 None
 0.95A 4pwdC-1wmiA:
undetectable		 4pwdC-1wmiA:
11.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q0B_A_NVPA901_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)		 1wmi HYPOTHETICAL PROTEIN
PHS013
(Pyrococcus
horikoshii) 		4 / 8 LEU A  33
VAL A  45
VAL A  66
TYR A  57
 None
 0.88A 4q0bA-1wmiA:
undetectable		 4q0bA-1wmiA:
11.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NWW_A_ACAA18_1
(SCRFP-TAG,GP41)		 1wmi HYPOTHETICAL PROTEIN
PHS014
(Pyrococcus
horikoshii) 		5 / 12 GLU B  43
LEU B  44
LEU B  45
GLU B  46
LEU B  47
 None
 0.69A 5nwwA-1wmiB:
undetectable		 5nwwA-1wmiB:
22.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOP_A_C2FA3001_1
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 1wmi HYPOTHETICAL PROTEIN
PHS013
(Pyrococcus
horikoshii) 		3 / 3 ASP A  74
ASN A  71
ASP A  53
 None
 0.77A 5vopA-1wmiA:
undetectable		 5vopA-1wmiA:
16.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOP_B_C2FB3001_1
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 1wmi HYPOTHETICAL PROTEIN
PHS013
(Pyrococcus
horikoshii) 		3 / 3 ASP A  74
ASN A  71
ASP A  53
 None
 0.80A 5vopB-1wmiA:
undetectable		 5vopB-1wmiA:
16.72