SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1wmr'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_L_TRPL81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 1wmr ISOPULLULANASE
(Aspergillus
niger) 		5 / 9 VAL A 397
GLY A 430
ALA A 468
ILE A 431
SER A 471
 None
 1.08A 1gtnL-1wmrA:
undetectable
1gtnM-1wmrA:
undetectable		 1gtnL-1wmrA:
9.54
1gtnM-1wmrA:
9.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_A_FUAA702_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 1wmr ISOPULLULANASE
(Aspergillus
niger) 		5 / 12 TYR A  55
SER A 121
LEU A 162
ALA A  98
ALA A 176
 None
 1.34A 1q23A-1wmrA:
undetectable
1q23B-1wmrA:
undetectable		 1q23A-1wmrA:
16.01
1q23B-1wmrA:
16.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1U70_A_MTXA187_2
(DIHYDROFOLATE
REDUCTASE)		 1wmr ISOPULLULANASE
(Aspergillus
niger) 		4 / 4 SER A 113
ILE A 112
VAL A  74
THR A  40
 None
 1.23A 1u70A-1wmrA:
undetectable		 1u70A-1wmrA:
15.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_P_CHDP4525_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE III)		 1wmr ISOPULLULANASE
(Aspergillus
niger) 		4 / 7 LEU A 207
ASP A 230
THR A 227
TYR A 225
 None
NAG  A1002 (-3.1A)
None
None
 0.90A 1v55C-1wmrA:
undetectable
1v55N-1wmrA:
undetectable
1v55P-1wmrA:
undetectable		 1v55C-1wmrA:
18.10
1v55N-1wmrA:
22.71
1v55P-1wmrA:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IYF_A_ERYA1400_0
(OLEANDOMYCIN
GLYCOSYLTRANSFERASE)		 1wmr ISOPULLULANASE
(Aspergillus
niger) 		5 / 11 TRP A 390
VAL A 345
ILE A 179
SER A 101
ASP A 416
 None
 1.38A 2iyfA-1wmrA:
undetectable		 2iyfA-1wmrA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PRG_B_BRLB2_1
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 1wmr ISOPULLULANASE
(Aspergillus
niger) 		5 / 12 LEU A 209
VAL A 217
HIS A 231
LEU A 296
TYR A 285
 None
 1.41A 2prgB-1wmrA:
undetectable		 2prgB-1wmrA:
18.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_N_CHDN1517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1wmr ISOPULLULANASE
(Aspergillus
niger) 		4 / 8 LEU A 207
ASP A 230
THR A 227
TYR A 225
 None
NAG  A1002 (-3.1A)
None
None
 0.81A 2y69C-1wmrA:
undetectable
2y69N-1wmrA:
undetectable
2y69P-1wmrA:
undetectable		 2y69C-1wmrA:
18.10
2y69N-1wmrA:
22.71
2y69P-1wmrA:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A35_A_RBFA191_1
(LUMAZINE PROTEIN)		 1wmr ISOPULLULANASE
(Aspergillus
niger) 		5 / 12 VAL A 269
SER A 271
THR A 316
ALA A 347
ASN A  81
 None
 1.11A 3a35A-1wmrA:
1.4		 3a35A-1wmrA:
17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A3B_A_RBFA191_1
(LUMAZINE PROTEIN)		 1wmr ISOPULLULANASE
(Aspergillus
niger) 		5 / 12 VAL A 269
SER A 271
THR A 316
ALA A 347
ASN A  81
 None
 1.15A 3a3bA-1wmrA:
undetectable		 3a3bA-1wmrA:
17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1wmr ISOPULLULANASE
(Aspergillus
niger) 		4 / 8 ASP A 230
THR A 227
TYR A 225
LEU A 207
 NAG  A1002 (-3.1A)
None
None
None
 0.93A 3ablA-1wmrA:
undetectable
3ablC-1wmrA:
undetectable
3ablP-1wmrA:
undetectable		 3ablA-1wmrA:
22.71
3ablC-1wmrA:
18.10
3ablP-1wmrA:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1wmr ISOPULLULANASE
(Aspergillus
niger) 		4 / 8 LEU A 207
ASP A 230
THR A 227
TYR A 225
 None
NAG  A1002 (-3.1A)
None
None
 0.91A 3ablC-1wmrA:
undetectable
3ablN-1wmrA:
undetectable
3ablP-1wmrA:
undetectable		 3ablC-1wmrA:
18.10
3ablN-1wmrA:
22.71
3ablP-1wmrA:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1wmr ISOPULLULANASE
(Aspergillus
niger) 		4 / 8 ASP A 230
THR A 227
TYR A 225
LEU A 207
 NAG  A1002 (-3.1A)
None
None
None
 0.92A 3abmA-1wmrA:
undetectable
3abmC-1wmrA:
undetectable
3abmP-1wmrA:
undetectable		 3abmA-1wmrA:
22.71
3abmC-1wmrA:
18.10
3abmP-1wmrA:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1wmr ISOPULLULANASE
(Aspergillus
niger) 		4 / 8 LEU A 207
ASP A 230
THR A 227
TYR A 225
 None
NAG  A1002 (-3.1A)
None
None
 0.88A 3asnC-1wmrA:
undetectable
3asnN-1wmrA:
undetectable
3asnP-1wmrA:
undetectable		 3asnC-1wmrA:
18.10
3asnN-1wmrA:
22.71
3asnP-1wmrA:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1wmr ISOPULLULANASE
(Aspergillus
niger) 		4 / 8 ASP A 230
THR A 227
TYR A 225
LEU A 207
 NAG  A1002 (-3.1A)
None
None
None
 0.90A 3asoA-1wmrA:
undetectable
3asoC-1wmrA:
undetectable
3asoP-1wmrA:
undetectable		 3asoA-1wmrA:
22.71
3asoC-1wmrA:
18.10
3asoP-1wmrA:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1wmr ISOPULLULANASE
(Aspergillus
niger) 		4 / 8 LEU A 207
ASP A 230
THR A 227
TYR A 225
 None
NAG  A1002 (-3.1A)
None
None
 0.91A 3asoC-1wmrA:
undetectable
3asoN-1wmrA:
undetectable
3asoP-1wmrA:
undetectable		 3asoC-1wmrA:
18.10
3asoN-1wmrA:
22.71
3asoP-1wmrA:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BC9_A_ACRA901_1
(ALPHA AMYLASE,
CATALYTIC REGION)		 1wmr ISOPULLULANASE
(Aspergillus
niger) 		4 / 7 SER A 289
LYS A 287
GLU A 283
ASP A 282
 None
 1.26A 3bc9A-1wmrA:
4.3		 3bc9A-1wmrA:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPB_C_SAMC1000_0
(UNCHARACTERIZED
PROTEIN MJ0100)		 1wmr ISOPULLULANASE
(Aspergillus
niger) 		5 / 12 ASP A 159
VAL A 141
ILE A 143
ILE A 125
SER A 155
 None
 1.28A 3kpbC-1wmrA:
undetectable		 3kpbC-1wmrA:
12.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PGH_C_FLPC701_1
(CYCLOOXYGENASE-2)		 1wmr ISOPULLULANASE
(Aspergillus
niger) 		5 / 12 VAL A 253
VAL A 217
VAL A 206
GLY A 208
LEU A 234
 None
 0.88A 3pghC-1wmrA:
undetectable		 3pghC-1wmrA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SXJ_A_SAMA258_0
(PUTATIVE
METHYLTRANSFERASE)		 1wmr ISOPULLULANASE
(Aspergillus
niger) 		5 / 12 GLY A 268
GLY A 266
LEU A 270
ALA A 247
TYR A 224
 None
 1.26A 3sxjA-1wmrA:
undetectable		 3sxjA-1wmrA:
17.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SXJ_B_SAMB258_0
(PUTATIVE
METHYLTRANSFERASE)		 1wmr ISOPULLULANASE
(Aspergillus
niger) 		5 / 12 GLY A 268
GLY A 266
LEU A 270
ALA A 247
TYR A 224
 None
 1.26A 3sxjB-1wmrA:
undetectable		 3sxjB-1wmrA:
17.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3S_E_9PLE1_1
(CYTOCHROME P450 2A13)		 1wmr ISOPULLULANASE
(Aspergillus
niger) 		4 / 8 PHE A 154
ALA A 181
ALA A 108
THR A  62
 None
 1.01A 3t3sE-1wmrA:
undetectable		 3t3sE-1wmrA:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TWP_D_SALD404_1
(ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE)		 1wmr ISOPULLULANASE
(Aspergillus
niger) 		4 / 5 ALA A 319
PRO A 320
TYR A 275
ALA A 252
 None
 1.21A 3twpD-1wmrA:
undetectable		 3twpD-1wmrA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UA5_A_06XA501_1
(CYTOCHROME P450 2B6)		 1wmr ISOPULLULANASE
(Aspergillus
niger) 		5 / 8 ILE A 528
ILE A 538
PHE A 531
GLU A 506
VAL A 552
 None
 1.25A 3ua5A-1wmrA:
undetectable		 3ua5A-1wmrA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1wmr ISOPULLULANASE
(Aspergillus
niger) 		4 / 8 ASP A 230
THR A 227
TYR A 225
LEU A 207
 NAG  A1002 (-3.1A)
None
None
None
 0.91A 3wg7A-1wmrA:
undetectable
3wg7C-1wmrA:
undetectable
3wg7P-1wmrA:
undetectable		 3wg7A-1wmrA:
22.71
3wg7C-1wmrA:
18.10
3wg7P-1wmrA:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1wmr ISOPULLULANASE
(Aspergillus
niger) 		4 / 8 LEU A 207
ASP A 230
THR A 227
TYR A 225
 None
NAG  A1002 (-3.1A)
None
None
 0.89A 3wg7C-1wmrA:
undetectable
3wg7N-1wmrA:
undetectable
3wg7P-1wmrA:
undetectable		 3wg7C-1wmrA:
18.10
3wg7N-1wmrA:
22.71
3wg7P-1wmrA:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1wmr ISOPULLULANASE
(Aspergillus
niger) 		4 / 8 ASP A 230
THR A 227
TYR A 225
LEU A 207
 NAG  A1002 (-3.1A)
None
None
None
 0.91A 3x2qA-1wmrA:
undetectable
3x2qC-1wmrA:
undetectable
3x2qP-1wmrA:
undetectable		 3x2qA-1wmrA:
22.71
3x2qC-1wmrA:
18.10
3x2qP-1wmrA:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_P_CHDP308_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1wmr ISOPULLULANASE
(Aspergillus
niger) 		4 / 8 LEU A 207
ASP A 230
THR A 227
TYR A 225
 None
NAG  A1002 (-3.1A)
None
None
 0.93A 3x2qC-1wmrA:
undetectable
3x2qN-1wmrA:
undetectable
3x2qP-1wmrA:
undetectable		 3x2qC-1wmrA:
18.10
3x2qN-1wmrA:
22.71
3x2qP-1wmrA:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AZS_A_SAMA1475_1
(METHYLTRANSFERASE
WBDD)		 1wmr ISOPULLULANASE
(Aspergillus
niger) 		3 / 3 ARG A 405
ASP A 372
GLN A 351
 None
 0.76A 4azsA-1wmrA:
undetectable		 4azsA-1wmrA:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MFL_B_GCSB502_1
(PUTATIVE
UNCHARACTERIZED
PROTEIN TCP24
TEICOPLANIN
PSEUDOAGLYCONE)		 1wmr ISOPULLULANASE
(Aspergillus
niger) 		4 / 6 GLN A 172
TRP A 390
ALA A 176
PHE A 348
 None
 1.39A 4mflA-1wmrA:
0.0		 4mflA-1wmrA:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MFQ_B_GCSB503_1
(PUTATIVE
UNCHARACTERIZED
PROTEIN TCP24
TEICOPLANIN
PSEUDOAGLYCONE)		 1wmr ISOPULLULANASE
(Aspergillus
niger) 		4 / 6 GLN A 172
TRP A 390
ALA A 176
PHE A 348
 None
 1.39A 4mfqA-1wmrA:
0.0		 4mfqA-1wmrA:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O8F_B_BRLB501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1wmr ISOPULLULANASE
(Aspergillus
niger) 		5 / 12 LEU A 209
VAL A 217
HIS A 231
LEU A 296
TYR A 285
 None
 1.31A 4o8fB-1wmrA:
0.0		 4o8fB-1wmrA:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y8W_C_STRC603_2
(CYTOCHROME P450
21-HYDROXYLASE)		 1wmr ISOPULLULANASE
(Aspergillus
niger) 		3 / 3 LEU A  28
VAL A  21
ASP A  71
 None
 0.52A 4y8wC-1wmrA:
undetectable		 4y8wC-1wmrA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1wmr ISOPULLULANASE
(Aspergillus
niger) 		4 / 8 ASP A 230
THR A 227
TYR A 225
LEU A 207
 NAG  A1002 (-3.1A)
None
None
None
 0.88A 5b1aA-1wmrA:
undetectable
5b1aC-1wmrA:
undetectable
5b1aP-1wmrA:
undetectable		 5b1aA-1wmrA:
22.71
5b1aC-1wmrA:
18.10
5b1aP-1wmrA:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1wmr ISOPULLULANASE
(Aspergillus
niger) 		4 / 8 ASP A 230
THR A 227
TYR A 225
LEU A 207
 NAG  A1002 (-3.1A)
None
None
None
 0.89A 5b3sA-1wmrA:
undetectable
5b3sC-1wmrA:
undetectable
5b3sP-1wmrA:
undetectable		 5b3sA-1wmrA:
22.71
5b3sC-1wmrA:
18.10
5b3sP-1wmrA:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CFS_A_TOYA203_1
(AAD(2''),GENTAMICIN
2''-NUCLEOTIDYLTRANS
FERASE,GENTAMICIN
RESISTANCE PROTEIN)		 1wmr ISOPULLULANASE
(Aspergillus
niger) 		5 / 8 ASP A 372
ASP A 353
TYR A 378
ASP A 373
ASP A 326
 None
 1.34A 5cfsA-1wmrA:
undetectable		 5cfsA-1wmrA:
15.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CFT_A_51GA204_1
(AMINOGLYCOSIDE
NUCLEOTIDYLTRANSFERA
SE (2')-IA)		 1wmr ISOPULLULANASE
(Aspergillus
niger) 		5 / 9 ASP A 372
ASP A 353
TYR A 378
ASP A 373
ASP A 326
 None
 1.30A 5cftA-1wmrA:
0.0		 5cftA-1wmrA:
15.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FA8_A_SAMA301_1
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE,
PUTATIVE)		 1wmr ISOPULLULANASE
(Aspergillus
niger) 		3 / 3 THR A  96
ASP A 161
GLU A 157
 None
 0.77A 5fa8A-1wmrA:
0.0		 5fa8A-1wmrA:
14.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKR_A_ID8A601_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1wmr ISOPULLULANASE
(Aspergillus
niger) 		3 / 3 VAL A 249
LEU A 355
MET A 325
 None
 0.63A 5ikrA-1wmrA:
undetectable		 5ikrA-1wmrA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1wmr ISOPULLULANASE
(Aspergillus
niger) 		4 / 8 LEU A 207
ASP A 230
THR A 227
TYR A 225
 None
NAG  A1002 (-3.1A)
None
None
 0.92A 5iy5C-1wmrA:
undetectable
5iy5N-1wmrA:
undetectable
5iy5P-1wmrA:
undetectable		 5iy5C-1wmrA:
17.39
5iy5N-1wmrA:
22.71
5iy5P-1wmrA:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MUG_A_VIVA301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 1wmr ISOPULLULANASE
(Aspergillus
niger) 		5 / 12 ILE A 418
TRP A 390
VAL A 141
VAL A 110
ILE A 179
 None
 0.99A 5mugA-1wmrA:
undetectable		 5mugA-1wmrA:
16.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N4T_B_BEZB306_0
(BETA-LACTAMASE VIM-2)		 1wmr ISOPULLULANASE
(Aspergillus
niger) 		3 / 3 HIS A 449
ASN A 448
ALA A 441
 None
NAG  A1004 (-2.1A)
None
 0.82A 5n4tB-1wmrA:
undetectable		 5n4tB-1wmrA:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TE8_A_08JA602_1
(CYTOCHROME P450 3A4)		 1wmr ISOPULLULANASE
(Aspergillus
niger) 		4 / 7 LEU A  54
THR A  40
ILE A  78
LEU A  76
 None
 0.84A 5te8A-1wmrA:
undetectable		 5te8A-1wmrA:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TE8_B_08JB602_1
(CYTOCHROME P450 3A4)		 1wmr ISOPULLULANASE
(Aspergillus
niger) 		4 / 8 LEU A  54
THR A  40
ILE A  78
LEU A  76
 None
 0.77A 5te8B-1wmrA:
undetectable		 5te8B-1wmrA:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1wmr ISOPULLULANASE
(Aspergillus
niger) 		4 / 8 ASP A 230
THR A 227
TYR A 225
LEU A 207
 NAG  A1002 (-3.1A)
None
None
None
 0.90A 5w97A-1wmrA:
undetectable
5w97C-1wmrA:
undetectable
5w97c-1wmrA:
undetectable		 5w97A-1wmrA:
22.71
5w97C-1wmrA:
18.10
5w97c-1wmrA:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_C_CHDC302_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1wmr ISOPULLULANASE
(Aspergillus
niger) 		4 / 7 LEU A 207
ASP A 230
THR A 227
TYR A 225
 None
NAG  A1002 (-3.1A)
None
None
 0.92A 5w97C-1wmrA:
undetectable
5w97a-1wmrA:
undetectable
5w97c-1wmrA:
undetectable		 5w97C-1wmrA:
18.10
5w97a-1wmrA:
22.71
5w97c-1wmrA:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1wmr ISOPULLULANASE
(Aspergillus
niger) 		4 / 8 ASP A 230
THR A 227
TYR A 225
LEU A 207
 NAG  A1002 (-3.1A)
None
None
None
 0.89A 5wauA-1wmrA:
undetectable
5wauC-1wmrA:
undetectable
5wauc-1wmrA:
undetectable		 5wauA-1wmrA:
22.71
5wauC-1wmrA:
18.10
5wauc-1wmrA:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_C_CHDC303_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1wmr ISOPULLULANASE
(Aspergillus
niger) 		4 / 7 LEU A 207
ASP A 230
THR A 227
TYR A 225
 None
NAG  A1002 (-3.1A)
None
None
 0.92A 5wauC-1wmrA:
undetectable
5waua-1wmrA:
undetectable
5wauc-1wmrA:
undetectable		 5wauC-1wmrA:
18.10
5waua-1wmrA:
22.71
5wauc-1wmrA:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1wmr ISOPULLULANASE
(Aspergillus
niger) 		4 / 8 ASP A 230
THR A 227
TYR A 225
LEU A 207
 NAG  A1002 (-3.1A)
None
None
None
 0.97A 5x19A-1wmrA:
undetectable
5x19C-1wmrA:
undetectable
5x19P-1wmrA:
undetectable		 5x19A-1wmrA:
22.71
5x19C-1wmrA:
18.10
5x19P-1wmrA:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1wmr ISOPULLULANASE
(Aspergillus
niger) 		4 / 7 ASP A 230
THR A 227
TYR A 225
LEU A 207
 NAG  A1002 (-3.1A)
None
None
None
 0.94A 5x1fA-1wmrA:
undetectable
5x1fC-1wmrA:
undetectable
5x1fP-1wmrA:
undetectable		 5x1fA-1wmrA:
22.71
5x1fC-1wmrA:
18.10
5x1fP-1wmrA:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X23_A_LSNA503_1
(CYTOCHROME P450 2C9)		 1wmr ISOPULLULANASE
(Aspergillus
niger) 		4 / 5 PRO A 359
GLY A 360
THR A 361
ASN A 381
 None
None
None
NAG  A1003 (-1.8A)
 1.15A 5x23A-1wmrA:
undetectable		 5x23A-1wmrA:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1wmr ISOPULLULANASE
(Aspergillus
niger) 		4 / 8 ASP A 230
THR A 227
TYR A 225
LEU A 207
 NAG  A1002 (-3.1A)
None
None
None
 0.90A 5xdqA-1wmrA:
undetectable
5xdqC-1wmrA:
undetectable
5xdqP-1wmrA:
undetectable		 5xdqA-1wmrA:
22.71
5xdqC-1wmrA:
18.10
5xdqP-1wmrA:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1wmr ISOPULLULANASE
(Aspergillus
niger) 		4 / 8 LEU A 207
ASP A 230
THR A 227
TYR A 225
 None
NAG  A1002 (-3.1A)
None
None
 0.88A 5xdqC-1wmrA:
undetectable
5xdqN-1wmrA:
undetectable
5xdqP-1wmrA:
undetectable		 5xdqC-1wmrA:
18.10
5xdqN-1wmrA:
22.71
5xdqP-1wmrA:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1wmr ISOPULLULANASE
(Aspergillus
niger) 		4 / 8 LEU A 207
ASP A 230
THR A 227
TYR A 225
 None
NAG  A1002 (-3.1A)
None
None
 0.89A 5xdxC-1wmrA:
undetectable
5xdxN-1wmrA:
undetectable
5xdxP-1wmrA:
undetectable		 5xdxC-1wmrA:
18.02
5xdxN-1wmrA:
22.71
5xdxP-1wmrA:
18.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XXI_A_LSNA502_1
(CYTOCHROME P450 2C9)		 1wmr ISOPULLULANASE
(Aspergillus
niger) 		4 / 6 PRO A 359
GLY A 360
THR A 361
ASN A 381
 None
None
None
NAG  A1003 (-1.8A)
 1.05A 5xxiA-1wmrA:
undetectable		 5xxiA-1wmrA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1wmr ISOPULLULANASE
(Aspergillus
niger) 		4 / 8 ASP A 230
THR A 227
TYR A 225
LEU A 207
 NAG  A1002 (-3.1A)
None
None
None
 0.90A 5z84A-1wmrA:
undetectable
5z84C-1wmrA:
undetectable
5z84P-1wmrA:
undetectable		 5z84A-1wmrA:
22.71
5z84C-1wmrA:
18.10
5z84P-1wmrA:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1wmr ISOPULLULANASE
(Aspergillus
niger) 		4 / 7 LEU A 207
ASP A 230
THR A 227
TYR A 225
 None
NAG  A1002 (-3.1A)
None
None
 0.90A 5z84C-1wmrA:
undetectable
5z84N-1wmrA:
undetectable
5z84P-1wmrA:
undetectable		 5z84C-1wmrA:
18.10
5z84N-1wmrA:
22.71
5z84P-1wmrA:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1wmr ISOPULLULANASE
(Aspergillus
niger) 		4 / 8 ASP A 230
THR A 227
TYR A 225
LEU A 207
 NAG  A1002 (-3.1A)
None
None
None
 0.88A 5z85A-1wmrA:
undetectable
5z85C-1wmrA:
undetectable
5z85P-1wmrA:
undetectable		 5z85A-1wmrA:
22.71
5z85C-1wmrA:
18.10
5z85P-1wmrA:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1wmr ISOPULLULANASE
(Aspergillus
niger) 		4 / 7 LEU A 207
ASP A 230
THR A 227
TYR A 225
 None
NAG  A1002 (-3.1A)
None
None
 0.90A 5z85C-1wmrA:
undetectable
5z85N-1wmrA:
undetectable
5z85P-1wmrA:
undetectable		 5z85C-1wmrA:
18.10
5z85N-1wmrA:
22.71
5z85P-1wmrA:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1wmr ISOPULLULANASE
(Aspergillus
niger) 		4 / 8 ASP A 230
THR A 227
TYR A 225
LEU A 207
 NAG  A1002 (-3.1A)
None
None
None
 0.86A 5z86A-1wmrA:
undetectable
5z86C-1wmrA:
undetectable
5z86P-1wmrA:
undetectable		 5z86A-1wmrA:
22.71
5z86C-1wmrA:
18.10
5z86P-1wmrA:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1wmr ISOPULLULANASE
(Aspergillus
niger) 		4 / 8 LEU A 207
ASP A 230
THR A 227
TYR A 225
 None
NAG  A1002 (-3.1A)
None
None
 0.89A 5z86C-1wmrA:
undetectable
5z86N-1wmrA:
undetectable
5z86P-1wmrA:
undetectable		 5z86C-1wmrA:
18.10
5z86N-1wmrA:
22.71
5z86P-1wmrA:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1wmr ISOPULLULANASE
(Aspergillus
niger) 		4 / 8 ASP A 230
THR A 227
TYR A 225
LEU A 207
 NAG  A1002 (-3.1A)
None
None
None
 0.90A 5zcoA-1wmrA:
undetectable
5zcoC-1wmrA:
undetectable
5zcoP-1wmrA:
undetectable		 5zcoA-1wmrA:
22.71
5zcoC-1wmrA:
18.10
5zcoP-1wmrA:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1wmr ISOPULLULANASE
(Aspergillus
niger) 		4 / 8 LEU A 207
ASP A 230
THR A 227
TYR A 225
 None
NAG  A1002 (-3.1A)
None
None
 0.88A 5zcoC-1wmrA:
undetectable
5zcoN-1wmrA:
undetectable
5zcoP-1wmrA:
undetectable		 5zcoC-1wmrA:
18.10
5zcoN-1wmrA:
22.71
5zcoP-1wmrA:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1wmr ISOPULLULANASE
(Aspergillus
niger) 		4 / 8 ASP A 230
THR A 227
TYR A 225
LEU A 207
 NAG  A1002 (-3.1A)
None
None
None
 0.88A 5zcpA-1wmrA:
undetectable
5zcpC-1wmrA:
undetectable
5zcpP-1wmrA:
undetectable		 5zcpA-1wmrA:
22.71
5zcpC-1wmrA:
18.10
5zcpP-1wmrA:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1wmr ISOPULLULANASE
(Aspergillus
niger) 		4 / 8 LEU A 207
ASP A 230
THR A 227
TYR A 225
 None
NAG  A1002 (-3.1A)
None
None
 0.90A 5zcpC-1wmrA:
undetectable
5zcpN-1wmrA:
undetectable
5zcpP-1wmrA:
undetectable		 5zcpC-1wmrA:
18.10
5zcpN-1wmrA:
22.71
5zcpP-1wmrA:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1wmr ISOPULLULANASE
(Aspergillus
niger) 		4 / 8 ASP A 230
THR A 227
TYR A 225
LEU A 207
 NAG  A1002 (-3.1A)
None
None
None
 0.87A 5zcqA-1wmrA:
undetectable
5zcqC-1wmrA:
undetectable
5zcqP-1wmrA:
undetectable		 5zcqA-1wmrA:
22.71
5zcqC-1wmrA:
18.10
5zcqP-1wmrA:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZSF_A_6T0A910_0
(TOLL-LIKE RECEPTOR 7)		 1wmr ISOPULLULANASE
(Aspergillus
niger) 		4 / 7 THR A 383
LEU A 411
ILE A 461
THR A 462
 None
NAG  A1006 (-3.6A)
None
NAG  A1006 ( 4.9A)
 1.03A 5zsfA-1wmrA:
1.5
5zsfB-1wmrA:
1.5		 5zsfA-1wmrA:
7.79
5zsfB-1wmrA:
7.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWD_A_GLYA717_0
(DEOXYNUCLEOSIDE
TRIPHOSPHATE
TRIPHOSPHOHYDROLASE
SAMHD1)		 1wmr ISOPULLULANASE
(Aspergillus
niger) 		4 / 5 SER A 182
ASP A 341
ARG A 153
LYS A 343
 None
 1.46A 6dwdA-1wmrA:
undetectable		 6dwdA-1wmrA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1wmr ISOPULLULANASE
(Aspergillus
niger) 		4 / 8 LEU A 207
ASP A 230
THR A 227
TYR A 225
 None
NAG  A1002 (-3.1A)
None
None
 0.93A 6nknC-1wmrA:
undetectable
6nknN-1wmrA:
undetectable
6nknP-1wmrA:
undetectable		 6nknC-1wmrA:
18.10
6nknN-1wmrA:
22.71
6nknP-1wmrA:
18.10