SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1wms'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7A_A_PFLA4002_1
(SERUM ALBUMIN)		 1wms RAS-RELATED PROTEIN
RAB-9A
(Homo
sapiens) 		3 / 3 PHE A  32
LEU A  23
SER A 154
 GDP  A1001 (-4.3A)
None
GDP  A1001 (-3.3A)
 0.73A 1e7aA-1wmsA:
1.4		 1e7aA-1wmsA:
16.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QOM_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE)		 1wms RAS-RELATED PROTEIN
RAB-9A
(Homo
sapiens) 		3 / 3 ARG A  78
ILE A  11
TRP A  61
 None
 1.15A 1qomA-1wmsA:
undetectable		 1qomA-1wmsA:
17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E6T_B_H4BB902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 1wms RAS-RELATED PROTEIN
RAB-9A
(Homo
sapiens) 		3 / 3 ARG A  78
ILE A  11
TRP A  61
 None
 1.21A 3e6tB-1wmsA:
undetectable		 3e6tB-1wmsA:
17.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E7I_B_H4BB2902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 1wms RAS-RELATED PROTEIN
RAB-9A
(Homo
sapiens) 		3 / 3 ARG A  78
ILE A  11
TRP A  61
 None
 1.08A 3e7iB-1wmsA:
undetectable		 3e7iB-1wmsA:
17.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NW2_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 1wms RAS-RELATED PROTEIN
RAB-9A
(Homo
sapiens) 		3 / 3 ARG A  78
ILE A  11
TRP A  61
 None
 1.05A 3nw2A-1wmsA:
undetectable		 3nw2A-1wmsA:
18.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NW2_B_H4BB902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 1wms RAS-RELATED PROTEIN
RAB-9A
(Homo
sapiens) 		3 / 3 ARG A  78
ILE A  11
TRP A  61
 None
 1.11A 3nw2B-1wmsA:
undetectable		 3nw2B-1wmsA:
18.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_E_ACTE503_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 1wms RAS-RELATED PROTEIN
RAB-9A
(Homo
sapiens) 		3 / 3 GLN A  59
THR A  57
ASN A  46
 None
 0.85A 3v4tE-1wmsA:
undetectable		 3v4tE-1wmsA:
16.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F6J_D_ACTD404_0
(L-LYSINE
3-HYDROXYLASE)		 1wms RAS-RELATED PROTEIN
RAB-9A
(Homo
sapiens) 		4 / 6 GLN A 139
GLU A 137
TRP A 141
ALA A 140
 None
 1.27A 6f6jC-1wmsA:
undetectable
6f6jD-1wmsA:
undetectable		 6f6jC-1wmsA:
19.78
6f6jD-1wmsA:
19.78