SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1wmu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LH6_A_NIOA155_1
(LEGHEMOGLOBIN A
(NICOTINATE MET))		 1wmu HEMOGLOBIN A AND D
BETA CHAIN
(Aldabrachelys
gigantea) 		4 / 7 PHE B  42
PHE B  45
VAL B  67
HIS B  92
 HEM  B 201 (-4.3A)
HEM  B 201 (-4.7A)
HEM  B 201 ( 4.0A)
HEM  B 201 (-3.4A)
 0.82A 1lh6A-1wmuB:
13.8		 1lh6A-1wmuB:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LH6_A_NIOA155_1
(LEGHEMOGLOBIN A
(NICOTINATE MET))		 1wmu HEMOGLOBIN D ALPHA
CHAIN
(Aldabrachelys
gigantea) 		4 / 7 PHE A  43
PHE A  46
VAL A  62
HIS A  87
 HEM  A 201 (-3.9A)
HEM  A 201 (-4.5A)
HEM  A 201 ( 4.2A)
HEM  A 201 (-3.4A)
 0.92A 1lh6A-1wmuA:
15.1		 1lh6A-1wmuA:
27.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_A_VDYA1002_2
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 1wmu HEMOGLOBIN A AND D
BETA CHAIN
(Aldabrachelys
gigantea) 		3 / 3 ILE B 111
LEU B 110
VAL B  23
 None
 0.46A 1mz9B-1wmuB:
undetectable		 1mz9B-1wmuB:
14.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TBF_A_VIAA501_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 1wmu HEMOGLOBIN A AND D
BETA CHAIN
(Aldabrachelys
gigantea) 		5 / 9 LEU B  68
LEU B 110
VAL B 137
ALA B 140
LEU B  88
 None
None
None
None
HEM  B 201 (-4.3A)
 1.27A 1tbfA-1wmuB:
undetectable		 1tbfA-1wmuB:
18.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_C_CHDC3525_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE III)		 1wmu HEMOGLOBIN D ALPHA
CHAIN
(Aldabrachelys
gigantea) 		4 / 7 TRP A  14
ASP A   6
TYR A 125
HIS A  72
 None
 1.49A 1v54A-1wmuA:
undetectable
1v54C-1wmuA:
undetectable		 1v54A-1wmuA:
14.09
1v54C-1wmuA:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_P_CHDP4525_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE III)		 1wmu HEMOGLOBIN D ALPHA
CHAIN
(Aldabrachelys
gigantea) 		4 / 7 TRP A  14
ASP A   6
TYR A 125
HIS A  72
 None
 1.45A 1v54N-1wmuA:
undetectable
1v54P-1wmuA:
undetectable		 1v54N-1wmuA:
14.09
1v54P-1wmuA:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXE_B_1FLB2002_1
(SERUM ALBUMIN)		 1wmu HEMOGLOBIN D ALPHA
CHAIN
(Aldabrachelys
gigantea) 		5 / 11 ALA A  69
LEU A  76
SER A  84
LEU A 136
VAL A 135
 None
None
None
HEM  A 201 (-4.9A)
None
 1.12A 2bxeB-1wmuA:
undetectable		 2bxeB-1wmuA:
14.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1wmu HEMOGLOBIN D ALPHA
CHAIN
(Aldabrachelys
gigantea) 		4 / 7 TRP A  14
ASP A   6
TYR A 125
HIS A  72
 None
 1.50A 2dyrA-1wmuA:
undetectable
2dyrC-1wmuA:
undetectable		 2dyrA-1wmuA:
14.09
2dyrC-1wmuA:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1wmu HEMOGLOBIN D ALPHA
CHAIN
(Aldabrachelys
gigantea) 		4 / 7 TRP A  14
ASP A   6
TYR A 125
HIS A  72
 None
 1.47A 2dyrN-1wmuA:
undetectable
2dyrP-1wmuA:
undetectable		 2dyrN-1wmuA:
14.09
2dyrP-1wmuA:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1wmu HEMOGLOBIN D ALPHA
CHAIN
(Aldabrachelys
gigantea) 		4 / 7 TRP A  14
ASP A   6
TYR A 125
HIS A  72
 None
 1.48A 2eijN-1wmuA:
undetectable
2eijP-1wmuA:
undetectable		 2eijN-1wmuA:
14.09
2eijP-1wmuA:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1wmu HEMOGLOBIN D ALPHA
CHAIN
(Aldabrachelys
gigantea) 		4 / 7 TRP A  14
ASP A   6
TYR A 125
HIS A  72
 None
 1.48A 2eikA-1wmuA:
undetectable
2eikC-1wmuA:
undetectable		 2eikA-1wmuA:
14.09
2eikC-1wmuA:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1wmu HEMOGLOBIN D ALPHA
CHAIN
(Aldabrachelys
gigantea) 		4 / 7 TRP A  14
ASP A   6
TYR A 125
HIS A  72
 None
 1.48A 2eikN-1wmuA:
undetectable
2eikP-1wmuA:
undetectable		 2eikN-1wmuA:
14.09
2eikP-1wmuA:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1wmu HEMOGLOBIN D ALPHA
CHAIN
(Aldabrachelys
gigantea) 		4 / 7 TRP A  14
ASP A   6
TYR A 125
HIS A  72
 None
 1.48A 2eilN-1wmuA:
undetectable
2eilP-1wmuA:
undetectable		 2eilN-1wmuA:
14.09
2eilP-1wmuA:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OUZ_A_C3DA999_0
(ESTROGEN RECEPTOR)		 1wmu HEMOGLOBIN D ALPHA
CHAIN
(Aldabrachelys
gigantea) 		5 / 12 LEU A   9
LEU A 129
GLY A 110
HIS A 112
LEU A 113
 None
 0.93A 2ouzA-1wmuA:
undetectable		 2ouzA-1wmuA:
18.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_A_CHDA1517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1wmu HEMOGLOBIN D ALPHA
CHAIN
(Aldabrachelys
gigantea) 		4 / 7 TRP A  14
ASP A   6
TYR A 125
HIS A  72
 None
 1.48A 2y69A-1wmuA:
undetectable
2y69C-1wmuA:
undetectable		 2y69A-1wmuA:
14.09
2y69C-1wmuA:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1wmu HEMOGLOBIN D ALPHA
CHAIN
(Aldabrachelys
gigantea) 		4 / 7 TRP A  14
ASP A   6
TYR A 125
HIS A  72
 None
 1.48A 3abkN-1wmuA:
undetectable
3abkP-1wmuA:
undetectable		 3abkN-1wmuA:
14.09
3abkP-1wmuA:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1wmu HEMOGLOBIN D ALPHA
CHAIN
(Aldabrachelys
gigantea) 		4 / 7 TRP A  14
ASP A   6
TYR A 125
HIS A  72
 None
 1.47A 3ag2N-1wmuA:
undetectable
3ag2P-1wmuA:
undetectable		 3ag2N-1wmuA:
14.09
3ag2P-1wmuA:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1wmu HEMOGLOBIN D ALPHA
CHAIN
(Aldabrachelys
gigantea) 		4 / 7 TRP A  14
ASP A   6
TYR A 125
HIS A  72
 None
 1.49A 3ag3N-1wmuA:
undetectable
3ag3P-1wmuA:
undetectable		 3ag3N-1wmuA:
14.09
3ag3P-1wmuA:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1wmu HEMOGLOBIN D ALPHA
CHAIN
(Aldabrachelys
gigantea) 		4 / 7 TRP A  14
ASP A   6
TYR A 125
HIS A  72
 None
 1.47A 3ag4A-1wmuA:
undetectable
3ag4C-1wmuA:
undetectable		 3ag4A-1wmuA:
14.09
3ag4C-1wmuA:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1wmu HEMOGLOBIN D ALPHA
CHAIN
(Aldabrachelys
gigantea) 		4 / 7 TRP A  14
ASP A   6
TYR A 125
HIS A  72
 None
 1.46A 3ag4N-1wmuA:
undetectable
3ag4P-1wmuA:
undetectable		 3ag4N-1wmuA:
14.09
3ag4P-1wmuA:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SMT_A_ACTA500_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD3)		 1wmu HEMOGLOBIN D ALPHA
CHAIN
(Aldabrachelys
gigantea) 		3 / 3 PHE A  46
SER A  52
GLN A  54
 HEM  A 201 (-4.5A)
None
None
 0.80A 3smtA-1wmuA:
1.7		 3smtA-1wmuA:
15.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OAD_A_CLMA205_0
(GNAT SUPERFAMILY
ACETYLTRANSFERASE
PA4794)		 1wmu HEMOGLOBIN D ALPHA
CHAIN
(Aldabrachelys
gigantea) 		5 / 12 CYH A 104
ALA A 111
GLY A 110
LEU A 113
TYR A 117
 None
 1.35A 4oadA-1wmuA:
undetectable		 4oadA-1wmuA:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1wmu HEMOGLOBIN D ALPHA
CHAIN
(Aldabrachelys
gigantea) 		4 / 7 TRP A  14
ASP A   6
TYR A 125
HIS A  72
 None
 1.49A 5b1aN-1wmuA:
undetectable
5b1aP-1wmuA:
undetectable		 5b1aN-1wmuA:
14.09
5b1aP-1wmuA:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1wmu HEMOGLOBIN D ALPHA
CHAIN
(Aldabrachelys
gigantea) 		4 / 7 TRP A  14
ASP A   6
TYR A 125
HIS A  72
 None
 1.47A 5b1bN-1wmuA:
2.4
5b1bP-1wmuA:
undetectable		 5b1bN-1wmuA:
14.09
5b1bP-1wmuA:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1wmu HEMOGLOBIN D ALPHA
CHAIN
(Aldabrachelys
gigantea) 		4 / 7 TRP A  14
ASP A   6
TYR A 125
HIS A  72
 None
 1.47A 5b3sN-1wmuA:
undetectable
5b3sP-1wmuA:
undetectable		 5b3sN-1wmuA:
14.09
5b3sP-1wmuA:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HRQ_I_IPHI101_0
(INSULIN A-CHAIN
INSULIN B-CHAIN)		 1wmu HEMOGLOBIN A AND D
BETA CHAIN
(Aldabrachelys
gigantea) 		4 / 6 VAL B 113
HIS B 117
LEU B 114
LEU B  68
 None
 1.13A 5hrqB-1wmuB:
undetectable
5hrqI-1wmuB:
undetectable
5hrqJ-1wmuB:
undetectable		 5hrqB-1wmuB:
13.01
5hrqI-1wmuB:
8.76
5hrqJ-1wmuB:
13.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1wmu HEMOGLOBIN D ALPHA
CHAIN
(Aldabrachelys
gigantea) 		4 / 7 TRP A  14
ASP A   6
TYR A 125
HIS A  72
 None
 1.48A 5iy5A-1wmuA:
undetectable
5iy5C-1wmuA:
undetectable		 5iy5A-1wmuA:
14.09
5iy5C-1wmuA:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KBW_A_RBFA201_1
(RIBOFLAVIN
TRANSPORTER RIBU)		 1wmu HEMOGLOBIN A AND D
BETA CHAIN
(Aldabrachelys
gigantea) 		5 / 12 LEU B 141
GLY B 107
ASN B 135
LEU B 133
ALA B  74
 HEM  B 201 (-4.6A)
None
None
None
None
 1.40A 5kbwA-1wmuB:
undetectable		 5kbwA-1wmuB:
23.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1wmu HEMOGLOBIN D ALPHA
CHAIN
(Aldabrachelys
gigantea) 		4 / 7 TRP A  14
ASP A   6
TYR A 125
HIS A  72
 None
 1.48A 5zcqN-1wmuA:
undetectable
5zcqP-1wmuA:
undetectable		 5zcqN-1wmuA:
14.09
5zcqP-1wmuA:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_H_PCFH604_0
(CYTOCHROME B-C1
COMPLEX SUBUNIT 8
CYTOCHROME C OXIDASE
POLYPEPTIDE 5A,
MITOCHONDRIAL)		 1wmu HEMOGLOBIN A AND D
BETA CHAIN
(Aldabrachelys
gigantea) 		4 / 8 GLY B  72
PHE B  71
GLY B  21
ALA B  27
 None
HEM  B 201 ( 4.3A)
None
None
 0.78A 6hu9H-1wmuB:
undetectable
6hu9e-1wmuB:
undetectable		 6hu9H-1wmuB:
24.29
6hu9e-1wmuB:
23.70