SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1wn0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N4F_A_ASRA141_0
(LYSOZYME C)		 1wn0 HISTIDINE-CONTAINING
PHOSPHOTRANSFER
PROTEIN
(Zea
mays) 		4 / 6 ASP A  36
GLY A  37
THR A  39
PRO A  40
 None
 0.77A 1n4fA-1wn0A:
undetectable		 1n4fA-1wn0A:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_W_CHDW4060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 1wn0 HISTIDINE-CONTAINING
PHOSPHOTRANSFER
PROTEIN
(Zea
mays) 		5 / 8 LEU A  30
PHE A  27
MET A 134
THR A 133
LEU A 135
 None
 1.35A 1v55N-1wn0A:
2.8
1v55W-1wn0A:
undetectable		 1v55N-1wn0A:
13.04
1v55W-1wn0A:
16.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_A_TEPA1436_1
(CHITINASE)		 1wn0 HISTIDINE-CONTAINING
PHOSPHOTRANSFER
PROTEIN
(Zea
mays) 		3 / 3 ASP A  55
PHE A 124
ARG A 128
 None
 0.86A 2a3aA-1wn0A:
undetectable		 2a3aA-1wn0A:
15.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 1wn0 HISTIDINE-CONTAINING
PHOSPHOTRANSFER
PROTEIN
(Zea
mays) 		5 / 8 LEU A  30
PHE A  27
MET A 134
THR A 133
LEU A 135
 None
 1.31A 2einA-1wn0A:
2.5
2einJ-1wn0A:
undetectable		 2einA-1wn0A:
13.04
2einJ-1wn0A:
16.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 1wn0 HISTIDINE-CONTAINING
PHOSPHOTRANSFER
PROTEIN
(Zea
mays) 		5 / 8 LEU A  30
PHE A  27
MET A 134
THR A 133
LEU A 135
 None
 1.38A 3abkA-1wn0A:
2.8
3abkJ-1wn0A:
undetectable		 3abkA-1wn0A:
13.04
3abkJ-1wn0A:
16.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 1wn0 HISTIDINE-CONTAINING
PHOSPHOTRANSFER
PROTEIN
(Zea
mays) 		5 / 8 LEU A  30
PHE A  27
MET A 134
THR A 133
LEU A 135
 None
 1.40A 3abmN-1wn0A:
2.8
3abmW-1wn0A:
undetectable		 3abmN-1wn0A:
13.04
3abmW-1wn0A:
16.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_W_CHDW1059_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 1wn0 HISTIDINE-CONTAINING
PHOSPHOTRANSFER
PROTEIN
(Zea
mays) 		5 / 8 LEU A  30
PHE A  27
MET A 134
THR A 133
LEU A 135
 None
 1.36A 3asoN-1wn0A:
2.7
3asoW-1wn0A:
undetectable		 3asoN-1wn0A:
13.04
3asoW-1wn0A:
16.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QX3_A_EVPA1_1
(DNA TOPOISOMERASE
2-BETA)		 1wn0 HISTIDINE-CONTAINING
PHOSPHOTRANSFER
PROTEIN
(Zea
mays) 		4 / 5 GLY A 112
ASP A 111
ARG A 110
GLN A 106
 None
 1.42A 3qx3A-1wn0A:
2.2		 3qx3A-1wn0A:
12.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9S_A_BEZA264_0
(CARNITINYL-COA
DEHYDRATASE)		 1wn0 HISTIDINE-CONTAINING
PHOSPHOTRANSFER
PROTEIN
(Zea
mays) 		4 / 6 ALA A  54
ILE A  58
LEU A  82
ALA A  91
 None
 0.83A 3r9sA-1wn0A:
undetectable		 3r9sA-1wn0A:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9S_C_BEZC264_0
(CARNITINYL-COA
DEHYDRATASE)		 1wn0 HISTIDINE-CONTAINING
PHOSPHOTRANSFER
PROTEIN
(Zea
mays) 		4 / 6 ALA A  54
ILE A  58
LEU A  82
ALA A  91
 None
 0.83A 3r9sC-1wn0A:
undetectable		 3r9sC-1wn0A:
21.17