SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1wn1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ACJ_A_THAA999_1
(ACETYLCHOLINESTERASE)		 1wn1 DIPEPTIDASE
(Pyrococcus
horikoshii) 		5 / 9 GLY A 191
GLU A 164
TYR A 323
ILE A 187
HIS A 199
 None
 1.24A 1acjA-1wn1A:
undetectable		 1acjA-1wn1A:
22.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4Y_A_TPVA501_1
(PROTEIN (HIV-1
PROTEASE))		 1wn1 DIPEPTIDASE
(Pyrococcus
horikoshii) 		5 / 10 LEU A 167
ILE A 182
GLY A 217
ILE A 227
VAL A 188
 None
 1.10A 1d4yA-1wn1A:
undetectable		 1d4yA-1wn1A:
14.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HRK_A_CHDA1501_0
(FERROCHELATASE)		 1wn1 DIPEPTIDASE
(Pyrococcus
horikoshii) 		5 / 12 LEU A  82
LEU A  41
ILE A  91
PRO A  22
VAL A  37
 None
 1.23A 1hrkA-1wn1A:
undetectable		 1hrkA-1wn1A:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JLB_A_NVPA999_1
(HIV-1 RT A-CHAIN)		 1wn1 DIPEPTIDASE
(Pyrococcus
horikoshii) 		4 / 8 LEU A 236
VAL A 330
GLY A 329
LEU A 353
 None
 0.82A 1jlbA-1wn1A:
undetectable		 1jlbA-1wn1A:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KNY_A_KANA558_1
(KANAMYCIN
NUCLEOTIDYLTRANSFERA
SE)		 1wn1 DIPEPTIDASE
(Pyrococcus
horikoshii) 		4 / 7 SER A 190
ASP A 210
GLU A 166
GLU A 203
 None
 0.98A 1knyA-1wn1A:
undetectable
1knyB-1wn1A:
undetectable		 1knyA-1wn1A:
21.14
1knyB-1wn1A:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KNY_B_KANB559_1
(KANAMYCIN
NUCLEOTIDYLTRANSFERA
SE)		 1wn1 DIPEPTIDASE
(Pyrococcus
horikoshii) 		4 / 8 GLU A 203
SER A 190
ASP A 210
GLU A 166
 None
 1.00A 1knyA-1wn1A:
undetectable
1knyB-1wn1A:
undetectable		 1knyA-1wn1A:
21.14
1knyB-1wn1A:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MAA_D_DMED999_1
(ACETYLCHOLINESTERASE)		 1wn1 DIPEPTIDASE
(Pyrococcus
horikoshii) 		4 / 8 GLY A 191
GLU A 164
TYR A 323
HIS A 199
 None
 0.98A 1maaD-1wn1A:
undetectable		 1maaD-1wn1A:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MEI_A_MOAA600_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE)		 1wn1 DIPEPTIDASE
(Pyrococcus
horikoshii) 		4 / 8 ASP A 105
ILE A  43
GLU A  39
GLY A  38
 None
 0.88A 1meiA-1wn1A:
undetectable		 1meiA-1wn1A:
23.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MX1_D_THAD4_2
(LIVER
CARBOXYLESTERASE I)		 1wn1 DIPEPTIDASE
(Pyrococcus
horikoshii) 		3 / 3 PHE A   6
LEU A 121
MET A 102
 None
 0.76A 1mx1D-1wn1A:
undetectable		 1mx1D-1wn1A:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NP1_A_HSMA303_1
(NITROPHORIN 1)		 1wn1 DIPEPTIDASE
(Pyrococcus
horikoshii) 		4 / 5 GLU A  99
LEU A  97
LEU A 121
LEU A  19
 None
 1.14A 1np1A-1wn1A:
undetectable		 1np1A-1wn1A:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RX3_A_MTXA161_2
(DIHYDROFOLATE
REDUCTASE)		 1wn1 DIPEPTIDASE
(Pyrococcus
horikoshii) 		3 / 3 LYS A 248
ILE A 322
THR A 288
 None
 0.77A 1rx3A-1wn1A:
undetectable		 1rx3A-1wn1A:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UWH_A_BAXA1723_2
(B-RAF PROTO-ONCOGENE
SERINE/THREONINE-PRO
TEIN KINASE)		 1wn1 DIPEPTIDASE
(Pyrococcus
horikoshii) 		4 / 6 ILE A 285
ILE A 212
ILE A 154
ASP A 215
 None
None
None
CO  A1003 (-2.8A)
 0.78A 1uwhA-1wn1A:
undetectable		 1uwhA-1wn1A:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UWH_B_BAXB1723_2
(B-RAF PROTO-ONCOGENE
SERINE/THREONINE-PRO
TEIN KINASE)		 1wn1 DIPEPTIDASE
(Pyrococcus
horikoshii) 		4 / 6 ILE A 285
ILE A 212
ILE A 154
ASP A 215
 None
None
None
CO  A1003 (-2.8A)
 0.79A 1uwhB-1wn1A:
undetectable		 1uwhB-1wn1A:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W0F_A_STRA1499_1
(CYTOCHROME P450 3A4)		 1wn1 DIPEPTIDASE
(Pyrococcus
horikoshii) 		4 / 4 PHE A 316
ASP A 334
PHE A 255
VAL A 258
 None
 1.31A 1w0fA-1wn1A:
0.0		 1w0fA-1wn1A:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KCE_A_D16A566_1
(THYMIDYLATE SYNTHASE)		 1wn1 DIPEPTIDASE
(Pyrococcus
horikoshii) 		5 / 12 GLU A 299
LEU A 310
ASP A 268
GLY A 303
ALA A 254
 None
 1.20A 2kceA-1wn1A:
undetectable		 2kceA-1wn1A:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4P_A_TPVA300_1
(PROTEASE)		 1wn1 DIPEPTIDASE
(Pyrococcus
horikoshii) 		5 / 11 LEU A 167
ILE A 182
GLY A 217
ILE A 227
VAL A 188
 None
 1.10A 2o4pA-1wn1A:
undetectable		 2o4pA-1wn1A:
14.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PIW_A_T3A932_1
(ANDROGEN RECEPTOR)		 1wn1 DIPEPTIDASE
(Pyrococcus
horikoshii) 		4 / 6 LEU A 167
LYS A 205
ILE A 212
ILE A 154
 None
 0.87A 2piwA-1wn1A:
undetectable		 2piwA-1wn1A:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO5_A_CHDA501_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1wn1 DIPEPTIDASE
(Pyrococcus
horikoshii) 		5 / 12 LEU A  82
LEU A  41
ILE A  91
PRO A  22
VAL A  37
 None
 1.21A 2po5A-1wn1A:
undetectable		 2po5A-1wn1A:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO7_B_CHDB501_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1wn1 DIPEPTIDASE
(Pyrococcus
horikoshii) 		5 / 12 LEU A  82
LEU A  41
ILE A  91
PRO A  22
VAL A  37
 None
 1.22A 2po7B-1wn1A:
undetectable		 2po7B-1wn1A:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5P_B_MK1B902_1
(PROTEASE)		 1wn1 DIPEPTIDASE
(Pyrococcus
horikoshii) 		5 / 12 LEU A 167
ILE A 182
GLY A 217
ILE A 227
VAL A 188
 None
 1.04A 2r5pA-1wn1A:
undetectable		 2r5pA-1wn1A:
15.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5P_D_MK1D902_1
(PROTEASE)		 1wn1 DIPEPTIDASE
(Pyrococcus
horikoshii) 		5 / 12 LEU A 167
ILE A 182
GLY A 217
ILE A 227
VAL A 188
 None
 1.03A 2r5pC-1wn1A:
undetectable		 2r5pC-1wn1A:
15.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5Q_B_1UNB900_1
(PROTEASE)		 1wn1 DIPEPTIDASE
(Pyrococcus
horikoshii) 		5 / 9 LEU A 167
ILE A 182
GLY A 217
ILE A 227
VAL A 188
 None
 1.18A 2r5qA-1wn1A:
undetectable		 2r5qA-1wn1A:
15.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5Q_D_1UND900_1
(PROTEASE)		 1wn1 DIPEPTIDASE
(Pyrococcus
horikoshii) 		5 / 9 LEU A 167
ILE A 182
GLY A 217
ILE A 227
VAL A 188
 None
 1.18A 2r5qC-1wn1A:
undetectable		 2r5qC-1wn1A:
15.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AQI_B_CHDB6_0
(FERROCHELATASE)		 1wn1 DIPEPTIDASE
(Pyrococcus
horikoshii) 		5 / 12 LEU A  82
LEU A  41
ILE A  91
PRO A  22
VAL A  37
 None
 1.19A 3aqiB-1wn1A:
undetectable		 3aqiB-1wn1A:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D1Y_A_ROCA201_2
(HIV-1 PROTEASE)		 1wn1 DIPEPTIDASE
(Pyrococcus
horikoshii) 		5 / 9 LEU A 167
ILE A 182
GLY A 217
ILE A 227
VAL A 188
 None
 1.04A 3d1yB-1wn1A:
undetectable		 3d1yB-1wn1A:
14.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FZG_A_SAMA300_0
(16S RRNA METHYLASE)		 1wn1 DIPEPTIDASE
(Pyrococcus
horikoshii) 		5 / 12 THR A 317
GLY A 293
GLY A 291
MET A 140
VAL A 137
 CO  A1001 ( 4.9A)
None
None
None
None
 1.15A 3fzgA-1wn1A:
undetectable		 3fzgA-1wn1A:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JAY_A_SAMA1101_0
(STRUCTURAL PROTEIN
VP3)		 1wn1 DIPEPTIDASE
(Pyrococcus
horikoshii) 		5 / 12 GLU A 319
ARG A 351
VAL A 258
ASP A 335
ILE A 336
 CO  A1001 (-2.6A)
None
None
None
None
 1.29A 3jayA-1wn1A:
undetectable		 3jayA-1wn1A:
15.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB3_A_SAMA1101_0
(STRUCTURAL PROTEIN
VP3)		 1wn1 DIPEPTIDASE
(Pyrococcus
horikoshii) 		5 / 12 GLU A 319
ARG A 351
VAL A 258
ASP A 335
ILE A 336
 CO  A1001 (-2.6A)
None
None
None
None
 1.28A 3jb3A-1wn1A:
undetectable		 3jb3A-1wn1A:
15.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MWS_B_017B201_2
(HIV-1 PROTEASE)		 1wn1 DIPEPTIDASE
(Pyrococcus
horikoshii) 		5 / 12 LEU A 167
ILE A 182
GLY A 217
ILE A 227
VAL A 188
 None
 1.02A 3mwsB-1wn1A:
undetectable		 3mwsB-1wn1A:
15.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3THR_C_C2FC1410_0
(GLYCINE
N-METHYLTRANSFERASE)		 1wn1 DIPEPTIDASE
(Pyrococcus
horikoshii) 		3 / 3 ARG A  13
PRO A 120
PHE A  15
 None
 0.81A 3thrC-1wn1A:
undetectable		 3thrC-1wn1A:
23.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W1W_A_CHDA1502_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1wn1 DIPEPTIDASE
(Pyrococcus
horikoshii) 		5 / 12 LEU A  82
LEU A  41
ILE A  91
PRO A  22
VAL A  37
 None
 1.18A 3w1wA-1wn1A:
undetectable		 3w1wA-1wn1A:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W1W_B_CHDB504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1wn1 DIPEPTIDASE
(Pyrococcus
horikoshii) 		5 / 12 LEU A  82
LEU A  41
ILE A  91
PRO A  22
VAL A  37
 None
 1.20A 3w1wB-1wn1A:
undetectable		 3w1wB-1wn1A:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GH8_A_MTXA201_2
(DIHYDROFOLATE
REDUCTASE)		 1wn1 DIPEPTIDASE
(Pyrococcus
horikoshii) 		3 / 3 LYS A 248
ILE A 322
THR A 288
 None
 0.77A 4gh8A-1wn1A:
undetectable		 4gh8A-1wn1A:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOU_A_C04A207_1
(UNCHARACTERIZED
PROTEIN)		 1wn1 DIPEPTIDASE
(Pyrococcus
horikoshii) 		3 / 3 GLY A 321
GLU A 319
THR A 288
 None
CO  A1001 (-2.6A)
None
 0.49A 4kouA-1wn1A:
undetectable		 4kouA-1wn1A:
17.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOV_A_KOVA204_1
(UNCHARACTERIZED
PROTEIN)		 1wn1 DIPEPTIDASE
(Pyrococcus
horikoshii) 		5 / 12 TYR A 301
PRO A 300
GLY A 289
ILE A 318
LEU A 310
 None
 1.48A 4kovA-1wn1A:
undetectable		 4kovA-1wn1A:
17.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XDQ_A_BEZA306_0
(GLYCOSIDE HYDROLASE
FAMILY PROTEIN)		 1wn1 DIPEPTIDASE
(Pyrococcus
horikoshii) 		3 / 3 ARG A 103
ASP A 105
TRP A 106
 None
 1.00A 4xdqA-1wn1A:
undetectable		 4xdqA-1wn1A:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BS8_G_MFXG101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 1wn1 DIPEPTIDASE
(Pyrococcus
horikoshii) 		4 / 7 ALA A 168
ASP A 210
ARG A 207
GLY A 161
 None
 0.83A 5bs8A-1wn1A:
undetectable
5bs8C-1wn1A:
undetectable
5bs8D-1wn1A:
undetectable		 5bs8A-1wn1A:
24.71
5bs8C-1wn1A:
24.71
5bs8D-1wn1A:
22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BS8_H_MFXH101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
GGTCATGAATGACTATGCAC
GTAA)		 1wn1 DIPEPTIDASE
(Pyrococcus
horikoshii) 		4 / 7 ALA A 168
ASP A 210
ARG A 207
GLY A 161
 None
 0.81A 5bs8A-1wn1A:
undetectable
5bs8B-1wn1A:
undetectable
5bs8C-1wn1A:
undetectable		 5bs8A-1wn1A:
24.71
5bs8B-1wn1A:
22.99
5bs8C-1wn1A:
24.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTD_E_GFNE101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
GGTCATGAATGACTATGCAC
GTAA)		 1wn1 DIPEPTIDASE
(Pyrococcus
horikoshii) 		4 / 7 ALA A 168
ASP A 210
ARG A 207
GLY A 161
 None
 0.83A 5btdA-1wn1A:
undetectable
5btdB-1wn1A:
undetectable
5btdC-1wn1A:
undetectable		 5btdA-1wn1A:
24.71
5btdB-1wn1A:
22.99
5btdC-1wn1A:
24.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTD_G_GFNG101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 1wn1 DIPEPTIDASE
(Pyrococcus
horikoshii) 		4 / 7 ALA A 168
ASP A 210
ARG A 207
GLY A 161
 None
 0.84A 5btdA-1wn1A:
undetectable
5btdC-1wn1A:
undetectable
5btdD-1wn1A:
undetectable		 5btdA-1wn1A:
24.71
5btdC-1wn1A:
24.71
5btdD-1wn1A:
22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTG_F_LFXF101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 1wn1 DIPEPTIDASE
(Pyrococcus
horikoshii) 		4 / 7 ALA A 168
ASP A 210
ARG A 207
GLY A 161
 None
 0.77A 5btgA-1wn1A:
undetectable
5btgC-1wn1A:
undetectable
5btgD-1wn1A:
undetectable		 5btgA-1wn1A:
24.71
5btgC-1wn1A:
24.71
5btgD-1wn1A:
22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JMN_A_FUAA1101_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 1wn1 DIPEPTIDASE
(Pyrococcus
horikoshii) 		4 / 5 ILE A 231
LYS A 170
ILE A 171
VAL A 188
 None
 1.01A 5jmnA-1wn1A:
undetectable		 5jmnA-1wn1A:
16.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JWA_A_ACTA612_0
(NADH DEHYDROGENASE,
PUTATIVE)		 1wn1 DIPEPTIDASE
(Pyrococcus
horikoshii) 		3 / 3 LYS A 221
ASP A 180
ARG A  33
 None
 0.80A 5jwaA-1wn1A:
undetectable
5jwaH-1wn1A:
undetectable		 5jwaA-1wn1A:
21.77
5jwaH-1wn1A:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KR1_B_017B101_1
(PROTEASE PR5-DRV)		 1wn1 DIPEPTIDASE
(Pyrococcus
horikoshii) 		5 / 10 LEU A 167
ILE A 182
GLY A 217
ILE A 227
VAL A 188
 None
 1.05A 5kr1A-1wn1A:
undetectable		 5kr1A-1wn1A:
14.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KR2_C_ROCC101_2
(PROTEASE PR5-SQV)		 1wn1 DIPEPTIDASE
(Pyrococcus
horikoshii) 		5 / 9 LEU A 167
ILE A 182
GLY A 217
ILE A 227
VAL A 188
 None
 1.01A 5kr2D-1wn1A:
undetectable		 5kr2D-1wn1A:
14.89