SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1wn9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1TBF_A_VIAA501_1 (CGMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE)	1wn9	THE HYPOTHETICAL PROTEIN (TT1805) (Thermus thermophilus)	5 / 9	LEU A 80 LEU A 21 VAL A 59 ALA A 47 LEU A 33	None	1.28A	1tbfA-1wn9A: undetectable	1tbfA-1wn9A: 17.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1Y7I_A_SALA501_1 (SALICYLIC ACID-BINDING PROTEIN 2)	1wn9	THE HYPOTHETICAL PROTEIN (TT1805) (Thermus thermophilus)	5 / 9	GLY A 85 ALA A 86 LEU A 26 PHE A 89 LEU A 50	None	1.03A	1y7iA-1wn9A: undetectable	1y7iA-1wn9A: 22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2A3A_A_TEPA1436_1 (CHITINASE)	1wn9	THE HYPOTHETICAL PROTEIN (TT1805) (Thermus thermophilus)	3 / 3	ASP A 61 PHE A 67 ARG A 45	None	0.90A	2a3aA-1wn9A: undetectable	2a3aA-1wn9A: 15.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2OAX_E_SNLE5001_1 (MINERALOCORTICOID RECEPTOR)	1wn9	THE HYPOTHETICAL PROTEIN (TT1805) (Thermus thermophilus)	5 / 12	LEU A 14 ALA A 73 LEU A 81 LEU A 33 PHE A 67	None	1.09A	2oaxE-1wn9A: undetectable	2oaxE-1wn9A: 21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3IJD_A_C2FA314_0 (UNCHARACTERIZED PROTEIN)	1wn9	THE HYPOTHETICAL PROTEIN (TT1805) (Thermus thermophilus)	5 / 12	THR A 52 LEU A 50 VAL A 4 GLY A 5 LEU A 21	None	1.13A	3ijdA-1wn9A: undetectable	3ijdA-1wn9A: 17.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6EW0_F_TA1F502_2 (TUBULIN BETA CHAIN)	1wn9	THE HYPOTHETICAL PROTEIN (TT1805) (Thermus thermophilus)	4 / 5	LEU A 102 LEU A 58 THR A 35 ARG A 88	None	1.07A	6ew0F-1wn9A: undetectable	6ew0F-1wn9A: 19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6EW0_G_TA1G501_2 (TUBULIN BETA CHAIN)	1wn9	THE HYPOTHETICAL PROTEIN (TT1805) (Thermus thermophilus)	4 / 6	LEU A 102 LEU A 58 THR A 35 ARG A 88	None	1.07A	6ew0G-1wn9A: undetectable	6ew0G-1wn9A: 19.51

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1TBF_A_VIAA501_1","CGMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE","1wn9","THE HYPOTHETICAL PROTEIN (TT1805)","Thermus thermophilus",5,"LEU A  80;LEU A  21;VAL A  59;ALA A  47;LEU A  33","None","1.28A","1tbfA-1wn9A:undetectable","1tbfA-1wn9A:17.24"],["1Y7I_A_SALA501_1","SALICYLIC ACID-BINDING PROTEIN 2","1wn9","THE HYPOTHETICAL PROTEIN (TT1805)","Thermus thermophilus",5,"GLY A  85;ALA A  86;LEU A  26;PHE A  89;LEU A  50","None","1.03A","1y7iA-1wn9A:undetectable","1y7iA-1wn9A:22.86"],["2A3A_A_TEPA1436_1","CHITINASE","1wn9","THE HYPOTHETICAL PROTEIN (TT1805)","Thermus thermophilus",3,"ASP A  61;PHE A  67;ARG A  45","None","0.90A","2a3aA-1wn9A:undetectable","2a3aA-1wn9A:15.63"],["2OAX_E_SNLE5001_1","MINERALOCORTICOID RECEPTOR","1wn9","THE HYPOTHETICAL PROTEIN (TT1805)","Thermus thermophilus",5,"LEU A  14;ALA A  73;LEU A  81;LEU A  33;PHE A  67","None","1.09A","2oaxE-1wn9A:undetectable","2oaxE-1wn9A:21.96"],["3IJD_A_C2FA314_0","UNCHARACTERIZED PROTEIN","1wn9","THE HYPOTHETICAL PROTEIN (TT1805)","Thermus thermophilus",5,"THR A  52;LEU A  50;VAL A   4;GLY A   5;LEU A  21","None","1.13A","3ijdA-1wn9A:undetectable","3ijdA-1wn9A:17.48"],["6EW0_F_TA1F502_2","TUBULIN BETA CHAIN","1wn9","THE HYPOTHETICAL PROTEIN (TT1805)","Thermus thermophilus",4,"LEU A 102;LEU A  58;THR A  35;ARG A  88","None","1.07A","6ew0F-1wn9A:undetectable","6ew0F-1wn9A:19.51"],["6EW0_G_TA1G501_2","TUBULIN BETA CHAIN","1wn9","THE HYPOTHETICAL PROTEIN (TT1805)","Thermus thermophilus",4,"LEU A 102;LEU A  58;THR A  35;ARG A  88","None","1.07A","6ew0G-1wn9A:undetectable","6ew0G-1wn9A:19.51"]]