SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1wnh'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM9_A_9CRA201_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1wnh LATEXIN
(Mus
musculus) 		3 / 3 GLN A 150
ILE A 187
HIS A 185
 None
 0.62A 1fm9A-1wnhA:
undetectable		 1fm9A-1wnhA:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K74_A_9CRA463_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1wnh LATEXIN
(Mus
musculus) 		3 / 3 GLN A 150
ILE A 187
HIS A 185
 None
 0.60A 1k74A-1wnhA:
undetectable		 1k74A-1wnhA:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZJQ_A_NCAA300_0
(PROTOGLOBIN)		 1wnh LATEXIN
(Mus
musculus) 		4 / 7 VAL A  74
VAL A  37
PHE A  56
ILE A  21
 None
 0.98A 3zjqA-1wnhA:
undetectable		 3zjqA-1wnhA:
22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZJQ_B_NCAB300_0
(PROTOGLOBIN)		 1wnh LATEXIN
(Mus
musculus) 		4 / 7 VAL A  74
VAL A  37
PHE A  56
ILE A  21
 None
 1.00A 3zjqB-1wnhA:
undetectable		 3zjqB-1wnhA:
22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HYT_A_OBNA1104_2
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 1wnh LATEXIN
(Mus
musculus) 		4 / 5 PRO A  99
ASP A 103
ILE A  62
VAL A 142
 None
 1.30A 4hytA-1wnhA:
0.0		 4hytA-1wnhA:
11.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH8_A_ACTA302_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 1wnh LATEXIN
(Mus
musculus) 		3 / 3 CYH A 144
MET A 148
ASN A 151
 None
 1.23A 5qh8A-1wnhA:
0.0		 5qh8A-1wnhA:
23.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z12_B_9CRB501_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 1wnh LATEXIN
(Mus
musculus) 		3 / 3 GLN A 150
ILE A 187
HIS A 185
 None
 0.48A 5z12B-1wnhA:
undetectable		 5z12B-1wnhA:
20.00