SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1wni'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7A_B_PFLB4002_1
(SERUM ALBUMIN)		 1wni TRIMERELYSIN II
(Protobothrops
flavoviridis) 		4 / 6 LEU A  53
VAL A  33
VAL A  13
GLN A  57
 None
 0.92A 1e7aB-1wniA:
undetectable		 1e7aB-1wniA:
16.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OS2_A_HAEA874_1
(MACROPHAGE
METALLOELASTASE)		 1wni TRIMERELYSIN II
(Protobothrops
flavoviridis) 		4 / 5 HIS A 142
GLU A 143
HIS A 146
HIS A 152
 ZN  A 999 (-3.5A)
ZN  A 999 ( 4.2A)
ZN  A 999 (-3.5A)
ZN  A 999 (-3.4A)
 0.16A 1os2A-1wniA:
9.2		 1os2A-1wniA:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OS2_D_HAED574_1
(MACROPHAGE
METALLOELASTASE)		 1wni TRIMERELYSIN II
(Protobothrops
flavoviridis) 		4 / 4 HIS A 142
GLU A 143
HIS A 146
HIS A 152
 ZN  A 999 (-3.5A)
ZN  A 999 ( 4.2A)
ZN  A 999 (-3.5A)
ZN  A 999 (-3.4A)
 0.18A 1os2D-1wniA:
10.9		 1os2D-1wniA:
20.48
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1R55_A_097A518_1
(ADAM 33)		 1wni TRIMERELYSIN II
(Protobothrops
flavoviridis) 		6 / 10 THR A 107
THR A 139
HIS A 142
GLU A 143
HIS A 146
HIS A 152
 None
None
ZN  A 999 (-3.5A)
ZN  A 999 ( 4.2A)
ZN  A 999 (-3.5A)
ZN  A 999 (-3.4A)
 0.31A 1r55A-1wniA:
30.7		 1r55A-1wniA:
34.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTT_A_HAEA1265_1
(MACROPHAGE
METALLOELASTASE)		 1wni TRIMERELYSIN II
(Protobothrops
flavoviridis) 		4 / 4 HIS A 142
GLU A 143
HIS A 146
HIS A 152
 ZN  A 999 (-3.5A)
ZN  A 999 ( 4.2A)
ZN  A 999 (-3.5A)
ZN  A 999 (-3.4A)
 0.18A 1uttA-1wniA:
11.2		 1uttA-1wniA:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTZ_A_HAEA1267_1
(MACROPHAGE
METALLOELASTASE)		 1wni TRIMERELYSIN II
(Protobothrops
flavoviridis) 		4 / 4 HIS A 142
GLU A 143
HIS A 146
HIS A 152
 ZN  A 999 (-3.5A)
ZN  A 999 ( 4.2A)
ZN  A 999 (-3.5A)
ZN  A 999 (-3.4A)
 0.20A 1utzA-1wniA:
11.1		 1utzA-1wniA:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTZ_B_HAEB1266_1
(MACROPHAGE
METALLOELASTASE)		 1wni TRIMERELYSIN II
(Protobothrops
flavoviridis) 		4 / 4 HIS A 142
GLU A 143
HIS A 146
HIS A 152
 ZN  A 999 (-3.5A)
ZN  A 999 ( 4.2A)
ZN  A 999 (-3.5A)
ZN  A 999 (-3.4A)
 0.21A 1utzB-1wniA:
11.1		 1utzB-1wniA:
20.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UUJ_B_ACTB1077_0
(PLATELET-ACTIVATING
FACTOR
ACETYLHYDROLASE IB
ALPHA SUBUNIT)		 1wni TRIMERELYSIN II
(Protobothrops
flavoviridis) 		3 / 3 ARG A  32
TYR A  22
LYS A  21
 None
 0.95A 1uujB-1wniA:
undetectable		 1uujB-1wniA:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XOT_A_VDNA101_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4B)		 1wni TRIMERELYSIN II
(Protobothrops
flavoviridis) 		5 / 12 HIS A  96
MET A 116
ILE A  40
SER A 181
ILE A 197
 None
 1.36A 1xotA-1wniA:
undetectable		 1xotA-1wniA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Y93_A_HAEA301_1
(MACROPHAGE
METALLOELASTASE)		 1wni TRIMERELYSIN II
(Protobothrops
flavoviridis) 		4 / 6 HIS A 142
GLU A 143
HIS A 146
HIS A 152
 ZN  A 999 (-3.5A)
ZN  A 999 ( 4.2A)
ZN  A 999 (-3.5A)
ZN  A 999 (-3.4A)
 0.21A 1y93A-1wniA:
11.2		 1y93A-1wniA:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZGY_A_BRLA503_2
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 1wni TRIMERELYSIN II
(Protobothrops
flavoviridis) 		5 / 5 ILE A  12
ILE A 197
ILE A  40
MET A 140
LEU A  87
 None
 1.26A 1zgyA-1wniA:
undetectable		 1zgyA-1wniA:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HU6_A_HAEA269_1
(MACROPHAGE
METALLOELASTASE)		 1wni TRIMERELYSIN II
(Protobothrops
flavoviridis) 		4 / 4 HIS A 142
GLU A 143
HIS A 146
HIS A 152
 ZN  A 999 (-3.5A)
ZN  A 999 ( 4.2A)
ZN  A 999 (-3.5A)
ZN  A 999 (-3.4A)
 0.16A 2hu6A-1wniA:
11.2		 2hu6A-1wniA:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JIH_A_097A1001_1
(ADAMTS-1)		 1wni TRIMERELYSIN II
(Protobothrops
flavoviridis) 		5 / 9 THR A 139
HIS A 142
GLU A 143
HIS A 146
HIS A 152
 None
ZN  A 999 (-3.5A)
ZN  A 999 ( 4.2A)
ZN  A 999 (-3.5A)
ZN  A 999 (-3.4A)
 0.26A 2jihA-1wniA:
26.3		 2jihA-1wniA:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JIH_B_097B1001_1
(ADAMTS-1)		 1wni TRIMERELYSIN II
(Protobothrops
flavoviridis) 		5 / 8 THR A 139
HIS A 142
GLU A 143
HIS A 146
HIS A 152
 None
ZN  A 999 (-3.5A)
ZN  A 999 ( 4.2A)
ZN  A 999 (-3.5A)
ZN  A 999 (-3.4A)
 0.29A 2jihB-1wniA:
26.3		 2jihB-1wniA:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OW9_A_HAEA502_1
(COLLAGENASE 3)		 1wni TRIMERELYSIN II
(Protobothrops
flavoviridis) 		4 / 6 HIS A 142
GLU A 143
HIS A 146
HIS A 152
 ZN  A 999 (-3.5A)
ZN  A 999 ( 4.2A)
ZN  A 999 (-3.5A)
ZN  A 999 (-3.4A)
 0.16A 2ow9A-1wniA:
10.9		 2ow9A-1wniA:
23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OW9_B_HAEB502_1
(COLLAGENASE 3)		 1wni TRIMERELYSIN II
(Protobothrops
flavoviridis) 		4 / 4 HIS A 142
GLU A 143
HIS A 146
HIS A 152
 ZN  A 999 (-3.5A)
ZN  A 999 ( 4.2A)
ZN  A 999 (-3.5A)
ZN  A 999 (-3.4A)
 0.19A 2ow9B-1wniA:
10.7		 2ow9B-1wniA:
23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZR_C_HAEC3001_1
(COLLAGENASE 3)		 1wni TRIMERELYSIN II
(Protobothrops
flavoviridis) 		4 / 4 HIS A 142
GLU A 143
HIS A 146
HIS A 152
 ZN  A 999 (-3.5A)
ZN  A 999 ( 4.2A)
ZN  A 999 (-3.5A)
ZN  A 999 (-3.4A)
 0.17A 2ozrC-1wniA:
10.5		 2ozrC-1wniA:
23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZR_D_HAED3002_1
(COLLAGENASE 3)		 1wni TRIMERELYSIN II
(Protobothrops
flavoviridis) 		4 / 4 HIS A 142
GLU A 143
HIS A 146
HIS A 152
 ZN  A 999 (-3.5A)
ZN  A 999 ( 4.2A)
ZN  A 999 (-3.5A)
ZN  A 999 (-3.4A)
 0.19A 2ozrD-1wniA:
10.6		 2ozrD-1wniA:
23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZR_E_HAEE3003_1
(COLLAGENASE 3)		 1wni TRIMERELYSIN II
(Protobothrops
flavoviridis) 		4 / 4 HIS A 142
GLU A 143
HIS A 146
HIS A 152
 ZN  A 999 (-3.5A)
ZN  A 999 ( 4.2A)
ZN  A 999 (-3.5A)
ZN  A 999 (-3.4A)
 0.26A 2ozrE-1wniA:
10.7		 2ozrE-1wniA:
23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZR_F_HAEF3004_1
(COLLAGENASE 3)		 1wni TRIMERELYSIN II
(Protobothrops
flavoviridis) 		3 / 3 HIS A 142
HIS A 146
HIS A 152
 ZN  A 999 (-3.5A)
ZN  A 999 (-3.5A)
ZN  A 999 (-3.4A)
 0.19A 2ozrF-1wniA:
10.6		 2ozrF-1wniA:
23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEI_A_CXXA801_1
(TRANSPORTER)		 1wni TRIMERELYSIN II
(Protobothrops
flavoviridis) 		5 / 11 LEU A  53
GLN A  35
ILE A  12
LEU A  98
ASP A 128
 None
 1.27A 2qeiA-1wniA:
undetectable		 2qeiA-1wniA:
15.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HY7_A_097A801_1
(A DISINTEGRIN AND
METALLOPROTEINASE
WITH THROMBOSPONDIN
MOTIFS 5)		 1wni TRIMERELYSIN II
(Protobothrops
flavoviridis) 		5 / 9 THR A 139
HIS A 142
GLU A 143
HIS A 146
HIS A 152
 None
ZN  A 999 (-3.5A)
ZN  A 999 ( 4.2A)
ZN  A 999 (-3.5A)
ZN  A 999 (-3.4A)
 0.22A 3hy7A-1wniA:
26.8		 3hy7A-1wniA:
28.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HY7_B_097B801_1
(A DISINTEGRIN AND
METALLOPROTEINASE
WITH THROMBOSPONDIN
MOTIFS 5)		 1wni TRIMERELYSIN II
(Protobothrops
flavoviridis) 		5 / 9 THR A 139
HIS A 142
GLU A 143
HIS A 146
HIS A 152
 None
ZN  A 999 (-3.5A)
ZN  A 999 ( 4.2A)
ZN  A 999 (-3.5A)
ZN  A 999 (-3.4A)
 0.22A 3hy7B-1wniA:
26.6		 3hy7B-1wniA:
28.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEC_A_HAEA272_1
(COLLAGENASE 3)		 1wni TRIMERELYSIN II
(Protobothrops
flavoviridis) 		4 / 5 HIS A 142
GLU A 143
HIS A 146
HIS A 152
 ZN  A 999 (-3.5A)
ZN  A 999 ( 4.2A)
ZN  A 999 (-3.5A)
ZN  A 999 (-3.4A)
 0.14A 3kecA-1wniA:
10.8		 3kecA-1wniA:
23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEC_B_HAEB271_1
(COLLAGENASE 3)		 1wni TRIMERELYSIN II
(Protobothrops
flavoviridis) 		3 / 3 HIS A 142
GLU A 143
HIS A 146
 ZN  A 999 (-3.5A)
ZN  A 999 ( 4.2A)
ZN  A 999 (-3.5A)
 0.12A 3kecB-1wniA:
10.7		 3kecB-1wniA:
23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LIK_A_HAEA302_1
(MACROPHAGE
METALLOELASTASE)		 1wni TRIMERELYSIN II
(Protobothrops
flavoviridis) 		4 / 5 HIS A 142
GLU A 143
HIS A 146
HIS A 152
 ZN  A 999 (-3.5A)
ZN  A 999 ( 4.2A)
ZN  A 999 (-3.5A)
ZN  A 999 (-3.4A)
 0.15A 3likA-1wniA:
11.2		 3likA-1wniA:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LIL_A_HAEA302_1
(MACROPHAGE
METALLOELASTASE)		 1wni TRIMERELYSIN II
(Protobothrops
flavoviridis) 		4 / 4 HIS A 142
GLU A 143
HIS A 146
HIS A 152
 ZN  A 999 (-3.5A)
ZN  A 999 ( 4.2A)
ZN  A 999 (-3.5A)
ZN  A 999 (-3.4A)
 0.17A 3lilA-1wniA:
11.3		 3lilA-1wniA:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LJG_A_HAEA301_1
(MACROPHAGE
METALLOELASTASE)		 1wni TRIMERELYSIN II
(Protobothrops
flavoviridis) 		5 / 5 ILE A 108
HIS A 142
GLU A 143
HIS A 146
HIS A 152
 None
ZN  A 999 (-3.5A)
ZN  A 999 ( 4.2A)
ZN  A 999 (-3.5A)
ZN  A 999 (-3.4A)
 1.49A 3ljgA-1wniA:
11.3		 3ljgA-1wniA:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LKA_A_HAEA269_1
(MACROPHAGE
METALLOELASTASE)		 1wni TRIMERELYSIN II
(Protobothrops
flavoviridis) 		4 / 5 HIS A 142
GLU A 143
HIS A 146
HIS A 152
 ZN  A 999 (-3.5A)
ZN  A 999 ( 4.2A)
ZN  A 999 (-3.5A)
ZN  A 999 (-3.4A)
 0.15A 3lkaA-1wniA:
11.2		 3lkaA-1wniA:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UT5_B_LOCB502_1
(TUBULIN BETA CHAIN)		 1wni TRIMERELYSIN II
(Protobothrops
flavoviridis) 		5 / 12 LEU A  47
LEU A 148
ASN A 147
MET A 116
ILE A 197
 None
 1.13A 3ut5B-1wniA:
undetectable		 3ut5B-1wniA:
15.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A7B_A_HAEA1273_1
(COLLAGENASE 3)		 1wni TRIMERELYSIN II
(Protobothrops
flavoviridis) 		4 / 6 HIS A 142
GLU A 143
HIS A 146
HIS A 152
 ZN  A 999 (-3.5A)
ZN  A 999 ( 4.2A)
ZN  A 999 (-3.5A)
ZN  A 999 (-3.4A)
 0.20A 4a7bA-1wniA:
10.5		 4a7bA-1wniA:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1I_D_LOCD502_1
(TUBULIN BETA CHAIN)		 1wni TRIMERELYSIN II
(Protobothrops
flavoviridis) 		5 / 12 LEU A  47
LEU A 148
ASN A 147
MET A 116
ILE A 197
 None
 1.05A 4x1iD-1wniA:
undetectable		 4x1iD-1wniA:
16.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1Y_B_LOCB502_1
(TUBULIN BETA CHAIN)		 1wni TRIMERELYSIN II
(Protobothrops
flavoviridis) 		5 / 12 LEU A  47
LEU A 148
ASN A 147
MET A 116
ILE A 197
 None
 1.05A 4x1yB-1wniA:
undetectable		 4x1yB-1wniA:
16.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1Y_D_LOCD502_2
(TUBULIN BETA CHAIN)		 1wni TRIMERELYSIN II
(Protobothrops
flavoviridis) 		5 / 12 LEU A  47
LEU A 148
ASN A 147
MET A 116
ILE A 197
 None
 1.03A 4x1yD-1wniA:
undetectable		 4x1yD-1wniA:
16.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X20_D_LOCD502_2
(TUBULIN BETA CHAIN)		 1wni TRIMERELYSIN II
(Protobothrops
flavoviridis) 		5 / 11 LEU A  47
LEU A 148
ASN A 147
MET A 116
ILE A 197
 None
 1.07A 4x20D-1wniA:
undetectable		 4x20D-1wniA:
16.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ITZ_B_LOCB502_1
(TUBULIN BETA-2B
CHAIN)		 1wni TRIMERELYSIN II
(Protobothrops
flavoviridis) 		5 / 12 LEU A  47
LEU A 148
ASN A 147
MET A 116
ILE A 197
 None
 1.06A 5itzB-1wniA:
undetectable		 5itzB-1wniA:
15.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N5J_A_HAEA306_1
(MACROPHAGE
METALLOELASTASE)		 1wni TRIMERELYSIN II
(Protobothrops
flavoviridis) 		4 / 4 HIS A 142
GLU A 143
HIS A 146
HIS A 152
 ZN  A 999 (-3.5A)
ZN  A 999 ( 4.2A)
ZN  A 999 (-3.5A)
ZN  A 999 (-3.4A)
 0.18A 5n5jA-1wniA:
11.3		 5n5jA-1wniA:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N5K_A_HAEA306_1
(MACROPHAGE
METALLOELASTASE)		 1wni TRIMERELYSIN II
(Protobothrops
flavoviridis) 		4 / 5 HIS A 142
GLU A 143
HIS A 146
HIS A 152
 ZN  A 999 (-3.5A)
ZN  A 999 ( 4.2A)
ZN  A 999 (-3.5A)
ZN  A 999 (-3.4A)
 0.18A 5n5kA-1wniA:
11.4		 5n5kA-1wniA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOO_D_C2FD3001_0
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 1wni TRIMERELYSIN II
(Protobothrops
flavoviridis) 		5 / 12 GLU A   9
ASN A  92
MET A 116
SER A  52
ILE A   8
 None
 1.13A 5vooD-1wniA:
undetectable		 5vooD-1wniA:
19.00