SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1wno'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E9L_A_GCSA800_1
(YM1 SECRETORY
PROTEIN)
1wno CHITINASE
(Aspergillus
fumigatus)
8 / 9 TYR A  10
PHE A  38
GLY A  98
ASP A 137
MET A 205
TYR A 207
ASP A 208
TRP A 346
None
0.82A 1e9lA-1wnoA:
42.9
1e9lA-1wnoA:
26.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MX1_D_THAD4_1
(LIVER
CARBOXYLESTERASE I)
1wno CHITINASE
(Aspergillus
fumigatus)
5 / 12 LEU A  35
GLY A 133
LEU A 161
LEU A 126
ILE A  96
None
0.89A 1mx1D-1wnoA:
undetectable
1mx1D-1wnoA:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UOB_A_PNNA1311_0
(DEACETOXYCEPHALOSPOR
IN C SYNTHETASE)
1wno CHITINASE
(Aspergillus
fumigatus)
5 / 12 LEU A 126
LEU A  26
VAL A  92
PHE A 131
ILE A  77
None
1.36A 1uobA-1wnoA:
undetectable
1uobA-1wnoA:
21.62
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2A3A_A_TEPA1433_1
(CHITINASE)
1wno CHITINASE
(Aspergillus
fumigatus)
10 / 11 TYR A  10
PHE A  38
GLY A  98
ASP A 137
GLU A 139
MET A 205
TYR A 207
ASP A 208
TYR A 261
TRP A 346
None
0.52A 2a3aA-1wnoA:
69.7
2a3aA-1wnoA:
99.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2A3A_A_TEPA1433_1
(CHITINASE)
1wno CHITINASE
(Aspergillus
fumigatus)
8 / 11 TYR A  10
PHE A  38
GLY A  98
TRP A  99
ASP A 137
GLU A 139
MET A 205
TRP A 346
None
0.82A 2a3aA-1wnoA:
69.7
2a3aA-1wnoA:
99.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2A3A_A_TEPA1434_1
(CHITINASE)
1wno CHITINASE
(Aspergillus
fumigatus)
3 / 3 TRP A  14
THR A 100
TYR A 101
None
0.14A 2a3aA-1wnoA:
69.7
2a3aA-1wnoA:
99.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2A3A_A_TEPA1435_1
(CHITINASE)
1wno CHITINASE
(Aspergillus
fumigatus)
3 / 3 TRP A  99
GLU A 139
TYR A 140
None
0.80A 2a3aA-1wnoA:
69.7
2a3aA-1wnoA:
99.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2A3A_A_TEPA1436_1
(CHITINASE)
1wno CHITINASE
(Aspergillus
fumigatus)
3 / 3 ASP A 208
PHE A 213
ARG A 263
None
0.24A 2a3aA-1wnoA:
69.7
2a3aA-1wnoA:
99.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2A3A_B_TEPB2433_1
(CHITINASE)
1wno CHITINASE
(Aspergillus
fumigatus)
8 / 9 PHE A  38
GLY A  98
GLU A 139
MET A 205
TYR A 207
ASP A 208
TYR A 261
TRP A 346
None
0.56A 2a3aB-1wnoA:
70.1
2a3aB-1wnoA:
99.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2A3A_B_TEPB2434_1
(CHITINASE)
1wno CHITINASE
(Aspergillus
fumigatus)
3 / 3 TRP A  14
THR A 100
TYR A 101
None
0.22A 2a3aB-1wnoA:
70.1
2a3aB-1wnoA:
99.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2A3B_A_CFFA1433_1
(CHITINASE)
1wno CHITINASE
(Aspergillus
fumigatus)
5 / 5 TRP A  99
TYR A 140
MET A 205
ASP A 208
PHE A 213
None
0.51A 2a3bA-1wnoA:
69.7
2a3bA-1wnoA:
99.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2A3B_A_CFFA1434_1
(CHITINASE)
1wno CHITINASE
(Aspergillus
fumigatus)
3 / 3 TRP A  14
THR A 100
TYR A 101
None
0.14A 2a3bA-1wnoA:
69.7
2a3bA-1wnoA:
99.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2A3B_A_CFFA1435_1
(CHITINASE)
1wno CHITINASE
(Aspergillus
fumigatus)
10 / 11 TYR A  10
PHE A  38
GLY A  98
TRP A  99
ASP A 137
GLU A 139
MET A 205
TYR A 207
ASP A 208
TRP A 346
None
0.73A 2a3bA-1wnoA:
69.7
2a3bA-1wnoA:
99.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2A3B_A_CFFA1435_1
(CHITINASE)
1wno CHITINASE
(Aspergillus
fumigatus)
10 / 11 TYR A  10
PHE A  38
GLY A  98
TRP A  99
ASP A 137
MET A 205
TYR A 207
ASP A 208
TYR A 261
TRP A 346
None
0.50A 2a3bA-1wnoA:
69.7
2a3bA-1wnoA:
99.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2A3B_B_CFFB2434_1
(CHITINASE)
1wno CHITINASE
(Aspergillus
fumigatus)
5 / 6 GLU A 139
TYR A 140
ASP A 208
PHE A 213
ARG A 263
None
0.72A 2a3bB-1wnoA:
69.9
2a3bB-1wnoA:
99.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2A3B_B_CFFB2435_1
(CHITINASE)
1wno CHITINASE
(Aspergillus
fumigatus)
9 / 10 PHE A  38
GLY A  98
ASP A 137
GLU A 139
MET A 205
TYR A 207
ASP A 208
TYR A 261
TRP A 346
None
0.69A 2a3bB-1wnoA:
69.9
2a3bB-1wnoA:
99.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2A3C_A_PNXA1434_1
(CHITINASE)
1wno CHITINASE
(Aspergillus
fumigatus)
10 / 12 TYR A  10
TRP A  14
PHE A  38
GLY A  98
ASP A 137
GLU A 139
MET A 205
TYR A 207
ASP A 208
TRP A 346
None
0.67A 2a3cA-1wnoA:
69.6
2a3cA-1wnoA:
99.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2A3C_A_PNXA1434_1
(CHITINASE)
1wno CHITINASE
(Aspergillus
fumigatus)
10 / 12 TYR A  10
TRP A  14
PHE A  38
GLY A  98
ASP A 137
MET A 205
TYR A 207
ASP A 208
TYR A 261
TRP A 346
None
0.41A 2a3cA-1wnoA:
69.6
2a3cA-1wnoA:
99.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2A3C_A_PNXA1435_1
(CHITINASE)
1wno CHITINASE
(Aspergillus
fumigatus)
4 / 6 TYR A 140
GLY A 211
SER A 214
ARG A 263
None
0.40A 2a3cA-1wnoA:
69.6
2a3cA-1wnoA:
99.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2A3C_B_PNXB2433_1
(CHITINASE)
1wno CHITINASE
(Aspergillus
fumigatus)
11 / 12 TRP A  14
PHE A  38
GLY A  98
THR A 100
ASP A 137
GLU A 139
MET A 205
TYR A 207
ASP A 208
TYR A 261
TRP A 346
None
0.64A 2a3cB-1wnoA:
69.9
2a3cB-1wnoA:
99.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2A3C_B_PNXB2434_1
(CHITINASE)
1wno CHITINASE
(Aspergillus
fumigatus)
4 / 6 TYR A 140
GLY A 211
SER A 214
ARG A 263
None
0.36A 2a3cB-1wnoA:
69.9
2a3cB-1wnoA:
99.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DTT_F_H4BF1005_1
(HYPOTHETICAL PROTEIN
PH0634)
1wno CHITINASE
(Aspergillus
fumigatus)
5 / 9 ILE A 320
TYR A 312
ASP A 313
PHE A 318
THR A 268
None
1.29A 2dttE-1wnoA:
0.0
2dttF-1wnoA:
0.0
2dttE-1wnoA:
14.90
2dttF-1wnoA:
14.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UY4_A_AZMA1311_1
(ENDOCHITINASE)
1wno CHITINASE
(Aspergillus
fumigatus)
7 / 9 TYR A  10
PHE A  38
GLY A  98
ASP A 137
GLU A 139
TYR A 207
TRP A 346
None
0.83A 2uy4A-1wnoA:
19.7
2uy4A-1wnoA:
25.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XTK_A_AZMA1339_1
(CLASS III CHITINASE
CHIA1)
1wno CHITINASE
(Aspergillus
fumigatus)
7 / 11 TYR A  10
PHE A  38
GLY A  98
ASP A 137
GLU A 139
TYR A 207
TRP A 346
None
0.92A 2xtkA-1wnoA:
21.1
2xtkA-1wnoA:
24.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XTK_B_AZMB1339_1
(CLASS III CHITINASE
CHIA1)
1wno CHITINASE
(Aspergillus
fumigatus)
7 / 10 TYR A  10
PHE A  38
GLY A  98
ASP A 137
GLU A 139
TYR A 207
TRP A 346
None
0.87A 2xtkB-1wnoA:
21.5
2xtkB-1wnoA:
24.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A27_A_SAMA250_0
(UNCHARACTERIZED
PROTEIN MJ1557)
1wno CHITINASE
(Aspergillus
fumigatus)
5 / 12 SER A 309
ASN A 225
ASP A 242
ARG A 245
TYR A 334
None
NDG  A1042 (-2.4A)
None
None
None
1.36A 3a27A-1wnoA:
undetectable
3a27A-1wnoA:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARQ_A_DM5A606_1
(CHITINASE A)
1wno CHITINASE
(Aspergillus
fumigatus)
4 / 6 TRP A  99
LYS A 186
ASP A 208
ARG A 263
None
0.92A 3arqA-1wnoA:
40.5
3arqA-1wnoA:
25.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARR_A_PNXA606_1
(CHITINASE A)
1wno CHITINASE
(Aspergillus
fumigatus)
5 / 7 TRP A  99
GLY A 183
LYS A 186
ASP A 208
ARG A 263
None
0.84A 3arrA-1wnoA:
41.1
3arrA-1wnoA:
25.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA606_1
(CHITINASE A)
1wno CHITINASE
(Aspergillus
fumigatus)
4 / 7 GLY A 183
LYS A 186
ASP A 208
ARG A 263
None
0.64A 3aruA-1wnoA:
40.8
3aruA-1wnoA:
25.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJ8_C_SPMC500_1
(DIAMINE
ACETYLTRANSFERASE 1)
1wno CHITINASE
(Aspergillus
fumigatus)
4 / 6 LEU A  80
ASP A 132
LEU A 175
HIS A  33
None
1.12A 3bj8C-1wnoA:
undetectable
3bj8D-1wnoA:
undetectable
3bj8C-1wnoA:
17.47
3bj8D-1wnoA:
17.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3G6M_A_CFFA1_1
(CHITINASE)
1wno CHITINASE
(Aspergillus
fumigatus)
11 / 11 TYR A  10
PHE A  38
GLY A  98
TRP A  99
ASP A 137
GLU A 139
MET A 205
TYR A 207
ASP A 208
TYR A 261
TRP A 346
None
0.57A 3g6mA-1wnoA:
24.3
3g6mA-1wnoA:
56.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3G6M_A_CFFA427_1
(CHITINASE)
1wno CHITINASE
(Aspergillus
fumigatus)
4 / 5 TRP A  99
TYR A 140
MET A 205
ASP A 208
None
0.42A 3g6mA-1wnoA:
24.3
3g6mA-1wnoA:
56.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JZJ_A_ACRA405_1
(ACARBOSE/MALTOSE
BINDING PROTEIN GACH)
1wno CHITINASE
(Aspergillus
fumigatus)
5 / 12 GLU A 284
ALA A 179
TRP A  14
GLY A  98
ASN A 203
None
1.24A 3jzjA-1wnoA:
undetectable
3jzjA-1wnoA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KMO_B_EAAB213_1
(GLUTATHIONE
S-TRANSFERASE P)
1wno CHITINASE
(Aspergillus
fumigatus)
4 / 7 TYR A 275
PHE A 265
VAL A 278
GLY A 286
None
1.07A 3kmoB-1wnoA:
undetectable
3kmoB-1wnoA:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WDM_A_ADNA901_1
(4-PHOSPHOPANTOATE--B
ETA-ALANINE LIGASE)
1wno CHITINASE
(Aspergillus
fumigatus)
5 / 9 ALA A 343
GLY A 257
LEU A 340
LEU A 204
ASN A 203
None
1.19A 3wdmA-1wnoA:
undetectable
3wdmA-1wnoA:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WQV_A_GCSA501_1
(CHITINASE)
1wno CHITINASE
(Aspergillus
fumigatus)
9 / 11 PHE A  38
GLY A  98
ASP A 137
GLU A 139
MET A 205
TYR A 207
ASP A 208
TYR A 261
TRP A 346
None
0.76A 3wqvA-1wnoA:
43.8
3wqvA-1wnoA:
29.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WQV_A_GCSA501_1
(CHITINASE)
1wno CHITINASE
(Aspergillus
fumigatus)
10 / 11 PHE A  38
GLY A  98
TRP A  99
GLU A 139
MET A 205
TYR A 207
ASP A 208
TYR A 261
ARG A 263
TRP A 346
None
0.54A 3wqvA-1wnoA:
43.8
3wqvA-1wnoA:
29.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WQW_A_GCSA501_1
(CHITINASE)
1wno CHITINASE
(Aspergillus
fumigatus)
9 / 11 PHE A  38
GLY A  98
ASP A 137
GLU A 139
MET A 205
TYR A 207
ASP A 208
TYR A 261
TRP A 346
None
0.79A 3wqwA-1wnoA:
43.8
3wqwA-1wnoA:
29.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WQW_A_GCSA501_1
(CHITINASE)
1wno CHITINASE
(Aspergillus
fumigatus)
10 / 11 PHE A  38
GLY A  98
TRP A  99
GLU A 139
MET A 205
TYR A 207
ASP A 208
TYR A 261
ARG A 263
TRP A 346
None
0.58A 3wqwA-1wnoA:
43.8
3wqwA-1wnoA:
29.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A83_A_DXCA1160_0
(MAJOR POLLEN
ALLERGEN BET V 1-A)
1wno CHITINASE
(Aspergillus
fumigatus)
5 / 12 PHE A 105
LEU A 192
ILE A 187
TYR A 244
ALA A 179
None
1.33A 4a83A-1wnoA:
undetectable
4a83A-1wnoA:
16.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JJK_A_FOLA601_0
(FORMATE--TETRAHYDROF
OLATE LIGASE)
1wno CHITINASE
(Aspergillus
fumigatus)
4 / 8 ASN A 203
ALA A 179
PRO A 181
TRP A 202
None
0.94A 4jjkA-1wnoA:
undetectable
4jjkA-1wnoA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_A_GCSA301_1
(CHITOSANASE)
1wno CHITINASE
(Aspergillus
fumigatus)
3 / 3 TYR A 310
GLY A 270
PRO A 271
None
0.69A 4qwpA-1wnoA:
undetectable
4qwpA-1wnoA:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XI3_D_29SD601_2
(ESTROGEN RECEPTOR)
1wno CHITINASE
(Aspergillus
fumigatus)
3 / 3 LEU A 190
ASP A 144
ILE A 136
None
0.67A 4xi3D-1wnoA:
undetectable
4xi3D-1wnoA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GQB_A_GCSA602_1
(CHITINASE)
1wno CHITINASE
(Aspergillus
fumigatus)
3 / 3 TRP A  99
GLU A 139
ASP A 208
None
0.50A 5gqbA-1wnoA:
43.3
5gqbA-1wnoA:
24.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GQB_A_GCSA603_1
(CHITINASE)
1wno CHITINASE
(Aspergillus
fumigatus)
8 / 8 PHE A  38
GLY A  98
TRP A  99
GLU A 139
TYR A 207
ASP A 208
ARG A 263
TRP A 346
None
0.66A 5gqbA-1wnoA:
43.3
5gqbA-1wnoA:
24.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODI_G_ACTG702_0
(HETERODISULFIDE
REDUCTASE, SUBUNIT A)
1wno CHITINASE
(Aspergillus
fumigatus)
3 / 3 GLY A 272
THR A 233
ASN A 229
None
0.69A 5odiG-1wnoA:
1.8
5odiG-1wnoA:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A94_B_ZOTB3001_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 2A,SOLUBLE
CYTOCHROME B562)
1wno CHITINASE
(Aspergillus
fumigatus)
5 / 12 VAL A   9
LEU A  26
VAL A  28
SER A   7
PHE A 201
None
1.12A 6a94B-1wnoA:
undetectable
6a94B-1wnoA:
22.63