SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1wod'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XVA_A_ACTA294_0
(GLYCINE
N-METHYLTRANSFERASE)		 1wod MODA
(Escherichia
coli) 		4 / 5 ILE A 127
LEU A  85
ALA A 132
GLU A 131
 None
 1.13A 1xvaA-1wodA:
undetectable
1xvaB-1wodA:
undetectable		 1xvaA-1wodA:
23.62
1xvaB-1wodA:
23.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1wod MODA
(Escherichia
coli) 		5 / 8 LEU A  80
PHE A 230
PHE A 225
LEU A 216
PHE A 212
 None
 1.28A 2eilP-1wodA:
undetectable
2eilW-1wodA:
undetectable		 2eilP-1wodA:
19.08
2eilW-1wodA:
17.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H77_A_T3A1_1
(THRA PROTEIN)		 1wod MODA
(Escherichia
coli) 		5 / 12 ALA A  10
ALA A  16
SER A  12
LEU A 216
ILE A  20
 WO4  A 234 (-3.3A)
None
WO4  A 234 ( 2.7A)
None
None
 1.12A 2h77A-1wodA:
undetectable		 2h77A-1wodA:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2I91_A_ACTA601_0
(60 KDA SS-A/RO
RIBONUCLEOPROTEIN)		 1wod MODA
(Escherichia
coli) 		4 / 7 TYR A 170
ALA A  11
SER A  12
SER A  38
 WO4  A 234 ( 4.5A)
WO4  A 234 (-3.7A)
WO4  A 234 ( 2.7A)
WO4  A 234 ( 4.4A)
 0.93A 2i91A-1wodA:
undetectable		 2i91A-1wodA:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2I91_B_ACTB602_0
(60 KDA SS-A/RO
RIBONUCLEOPROTEIN)		 1wod MODA
(Escherichia
coli) 		4 / 7 TYR A 170
ALA A  11
SER A  12
SER A  38
 WO4  A 234 ( 4.5A)
WO4  A 234 (-3.7A)
WO4  A 234 ( 2.7A)
WO4  A 234 ( 4.4A)
 0.92A 2i91B-1wodA:
undetectable		 2i91B-1wodA:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_F_ASDF1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 1wod MODA
(Escherichia
coli) 		4 / 8 LEU A 115
LEU A 146
ALA A 155
ALA A 125
 None
None
None
WO4  A 234 ( 3.5A)
 0.87A 2vcvF-1wodA:
undetectable		 2vcvF-1wodA:
23.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VH3_A_DAHA2_1
(RANASMURFIN)		 1wod MODA
(Escherichia
coli) 		5 / 9 ALA A  58
ALA A   9
SER A  35
SER A  12
ALA A  11
 WO4  A 234 (-3.6A)
None
None
WO4  A 234 ( 2.7A)
WO4  A 234 (-3.7A)
 1.46A 2vh3A-1wodA:
0.0		 2vh3A-1wodA:
16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_C_CHDC1265_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1wod MODA
(Escherichia
coli) 		4 / 5 PHE A 230
PHE A 225
LEU A 216
PHE A 212
 None
 1.36A 2y69C-1wodA:
undetectable
2y69J-1wodA:
undetectable		 2y69C-1wodA:
19.08
2y69J-1wodA:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1wod MODA
(Escherichia
coli) 		4 / 6 LEU A  80
PHE A 230
PHE A 225
LEU A 216
 None
 1.01A 3abkP-1wodA:
undetectable
3abkW-1wodA:
undetectable		 3abkP-1wodA:
19.08
3abkW-1wodA:
17.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1wod MODA
(Escherichia
coli) 		4 / 5 PHE A 230
PHE A 225
LEU A 216
PHE A 212
 None
 1.36A 3abmC-1wodA:
undetectable
3abmJ-1wodA:
undetectable		 3abmC-1wodA:
19.08
3abmJ-1wodA:
17.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1wod MODA
(Escherichia
coli) 		4 / 5 PHE A 230
PHE A 225
LEU A 216
PHE A 212
 None
 1.36A 3abmP-1wodA:
undetectable
3abmW-1wodA:
undetectable		 3abmP-1wodA:
19.08
3abmW-1wodA:
17.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1wod MODA
(Escherichia
coli) 		5 / 6 LEU A  80
PHE A 230
PHE A 225
LEU A 216
PHE A 212
 None
 1.27A 3wg7P-1wodA:
undetectable
3wg7W-1wodA:
undetectable		 3wg7P-1wodA:
19.08
3wg7W-1wodA:
17.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K39_A_SAMA504_0
(ANAEROBIC
SULFATASE-MATURATING
ENZYME)		 1wod MODA
(Escherichia
coli) 		5 / 12 TYR A 213
PHE A 212
LEU A  81
VAL A 198
ILE A  56
 None
 1.25A 4k39A-1wodA:
undetectable		 4k39A-1wodA:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LMN_A_EUIA503_2
(DUAL SPECIFICITY
MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE 1)		 1wod MODA
(Escherichia
coli) 		3 / 3 ASP A 173
VAL A 183
ASN A  83
 None
 0.67A 4lmnA-1wodA:
undetectable		 4lmnA-1wodA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LNW_A_T3A501_1
(THYROID HORMONE
RECEPTOR ALPHA)		 1wod MODA
(Escherichia
coli) 		5 / 12 ALA A  10
ALA A  16
SER A  12
LEU A 216
ILE A  20
 WO4  A 234 (-3.3A)
None
WO4  A 234 ( 2.7A)
None
None
 1.14A 4lnwA-1wodA:
undetectable		 4lnwA-1wodA:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LNX_A_T3A502_1
(THYROID HORMONE
RECEPTOR ALPHA)		 1wod MODA
(Escherichia
coli) 		5 / 12 ALA A  10
ALA A  16
SER A  12
LEU A 216
ILE A  20
 WO4  A 234 (-3.3A)
None
WO4  A 234 ( 2.7A)
None
None
 1.14A 4lnxA-1wodA:
undetectable		 4lnxA-1wodA:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JW1_B_CELB602_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1wod MODA
(Escherichia
coli) 		4 / 6 VAL A 175
VAL A  88
ILE A 100
PHE A 186
 None
 1.00A 5jw1B-1wodA:
undetectable		 5jw1B-1wodA:
18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODI_G_ACTG702_0
(HETERODISULFIDE
REDUCTASE, SUBUNIT A)		 1wod MODA
(Escherichia
coli) 		3 / 3 GLY A 229
THR A 231
ASN A  83
 None
 0.65A 5odiG-1wodA:
undetectable		 5odiG-1wodA:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1wod MODA
(Escherichia
coli) 		4 / 5 PHE A 230
PHE A 225
LEU A 216
PHE A 212
 None
 1.31A 5wauC-1wodA:
undetectable
5wauJ-1wodA:
undetectable		 5wauC-1wodA:
19.08
5wauJ-1wodA:
17.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_C_CHDC308_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1wod MODA
(Escherichia
coli) 		4 / 5 PHE A 230
PHE A 225
LEU A 216
PHE A 212
 None
 1.31A 5wauc-1wodA:
undetectable
5wauj-1wodA:
undetectable		 5wauc-1wodA:
19.08
5wauj-1wodA:
17.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3)		 1wod MODA
(Escherichia
coli) 		4 / 5 LEU A  80
PHE A 230
PHE A 225
LEU A 216
 None
 1.02A 5x1bP-1wodA:
undetectable		 5x1bP-1wodA:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_C_CHDC307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1wod MODA
(Escherichia
coli) 		5 / 7 LEU A  80
PHE A 230
PHE A 225
LEU A 216
PHE A 212
 None
 1.36A 5z84C-1wodA:
undetectable
5z84J-1wodA:
undetectable		 5z84C-1wodA:
19.08
5z84J-1wodA:
17.10