SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1woi'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FDU_A_ESTA351_1
(17-BETA-HYDROXYSTERO
ID DEHYDROGENASE)		 1woi AGMATINASE
(Deinococcus
radiodurans) 		6 / 12 VAL A  36
LEU A 127
GLY A 119
TYR A 225
LEU A 270
SER A 227
 None
 1.31A 1fduA-1woiA:
2.2		 1fduA-1woiA:
25.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_A_TEPA1436_1
(CHITINASE)		 1woi AGMATINASE
(Deinococcus
radiodurans) 		3 / 3 ASP A  30
PHE A 301
ARG A 112
 None
 0.81A 2a3aA-1woiA:
undetectable		 2a3aA-1woiA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KCE_A_D16A566_1
(THYMIDYLATE SYNTHASE)		 1woi AGMATINASE
(Deinococcus
radiodurans) 		5 / 12 LEU A 117
GLY A 269
PHE A 226
VAL A  31
ALA A  32
 None
 1.23A 2kceA-1woiA:
undetectable		 2kceA-1woiA:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_A_HSMA1160_1
(ALLERGEN ARG R 1)		 1woi AGMATINASE
(Deinococcus
radiodurans) 		4 / 6 SER A 124
TYR A 225
VAL A 139
ASP A 271
 None
 1.13A 2x45A-1woiA:
undetectable		 2x45A-1woiA:
17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_B_HSMB1160_1
(ALLERGEN ARG R 1)		 1woi AGMATINASE
(Deinococcus
radiodurans) 		4 / 7 SER A 124
TYR A 225
VAL A 139
ASP A 271
 None
 1.12A 2x45B-1woiA:
undetectable		 2x45B-1woiA:
17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X45_C_HSMC1160_1
(ALLERGEN ARG R 1)		 1woi AGMATINASE
(Deinococcus
radiodurans) 		4 / 7 SER A 124
TYR A 225
VAL A 139
ASP A 271
 None
 1.14A 2x45C-1woiA:
undetectable		 2x45C-1woiA:
17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A2Q_A_ACAA602_1
(6-AMINOHEXANOATE-CYC
LIC-DIMER HYDROLASE)		 1woi AGMATINASE
(Deinococcus
radiodurans) 		4 / 7 ALA A  32
ALA A  81
ALA A  83
GLN A  28
 None
 0.87A 3a2qA-1woiA:
undetectable		 3a2qA-1woiA:
22.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CJT_C_SAMC302_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 1woi AGMATINASE
(Deinococcus
radiodurans) 		5 / 12 ASP A 143
LEU A 142
GLY A 232
ASP A 234
LEU A 292
 MN  A1501 ( 2.4A)
None
None
None
None
 0.97A 3cjtC-1woiA:
undetectable		 3cjtC-1woiA:
25.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QXV_D_MTXD2000_2
(ANTI-METHOTREXATE
CDR1-4 GRAFT VHH)		 1woi AGMATINASE
(Deinococcus
radiodurans) 		3 / 3 LEU A 181
ARG A 164
ASN A 159
 None
 0.67A 3qxvD-1woiA:
undetectable		 3qxvD-1woiA:
19.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CEV_A_GAIA407_0
(PROTEIN (ARGINASE))		 1woi AGMATINASE
(Deinococcus
radiodurans) 		4 / 6 ARG A 284
GLU A 286
LEU A 275
ASP A 280
 None
 1.47A 4cevA-1woiA:
32.4
4cevB-1woiA:
32.6		 4cevA-1woiA:
29.41
4cevB-1woiA:
29.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CEV_C_GAIC409_0
(PROTEIN (ARGINASE))		 1woi AGMATINASE
(Deinococcus
radiodurans) 		4 / 6 ASP A 280
ARG A 284
GLU A 286
LEU A 275
 None
 1.45A 4cevA-1woiA:
32.4
4cevC-1woiA:
32.5		 4cevA-1woiA:
29.41
4cevC-1woiA:
29.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CEV_D_GAID410_0
(PROTEIN (ARGINASE))		 1woi AGMATINASE
(Deinococcus
radiodurans) 		4 / 6 ARG A 284
GLU A 286
LEU A 275
ASP A 280
 None
 1.48A 4cevD-1woiA:
32.6
4cevE-1woiA:
32.6		 4cevD-1woiA:
29.41
4cevE-1woiA:
29.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CEV_F_GAIF411_0
(PROTEIN (ARGINASE))		 1woi AGMATINASE
(Deinococcus
radiodurans) 		4 / 6 ARG A 284
GLU A 286
LEU A 275
ASP A 280
 None
 1.47A 4cevE-1woiA:
32.6
4cevF-1woiA:
32.6		 4cevE-1woiA:
29.41
4cevF-1woiA:
29.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FFW_B_715B801_2
(DIPEPTIDYL PEPTIDASE
4)		 1woi AGMATINASE
(Deinococcus
radiodurans) 		3 / 3 ARG A 164
TYR A 225
ASN A 172
 None
 0.86A 4ffwB-1woiA:
undetectable		 4ffwB-1woiA:
14.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GRK_A_KTRA713_1
(LACTOTRANSFERRIN)		 1woi AGMATINASE
(Deinococcus
radiodurans) 		4 / 5 THR A 178
GLY A 180
VAL A 207
PRO A 203
 None
 1.16A 4grkA-1woiA:
undetectable		 4grkA-1woiA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HFP_D_15UD402_1
(PROTHROMBIN)		 1woi AGMATINASE
(Deinococcus
radiodurans) 		5 / 12 LEU A 127
ASP A  82
ALA A  83
ALA A 103
VAL A 107
 None
 1.14A 4hfpD-1woiA:
undetectable		 4hfpD-1woiA:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MUB_A_OAQA302_0
(SULFOTRANSFERASE)		 1woi AGMATINASE
(Deinococcus
radiodurans) 		5 / 12 MET A 294
LEU A  75
VAL A  31
GLY A  84
ASP A  82
 None
 1.44A 4mubA-1woiA:
undetectable		 4mubA-1woiA:
18.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P65_G_IPHG101_0
(INSULIN)		 1woi AGMATINASE
(Deinococcus
radiodurans) 		5 / 11 LEU A 258
VAL A 214
LEU A 211
LEU A 142
LEU A 249
 None
 1.09A 4p65B-1woiA:
undetectable
4p65D-1woiA:
undetectable
4p65G-1woiA:
undetectable
4p65H-1woiA:
undetectable		 4p65B-1woiA:
8.37
4p65D-1woiA:
8.37
4p65G-1woiA:
4.50
4p65H-1woiA:
8.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KVA_A_SAMA301_1
(CAFFEOYL-COA
O-METHYLTRANSFERASE)		 1woi AGMATINASE
(Deinococcus
radiodurans) 		3 / 3 THR A 155
SER A 158
ASP A 187
 None
 0.63A 5kvaA-1woiA:
2.6		 5kvaA-1woiA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KVA_B_SAMB301_1
(CAFFEOYL-COA
O-METHYLTRANSFERASE)		 1woi AGMATINASE
(Deinococcus
radiodurans) 		3 / 3 THR A 155
SER A 158
ASP A 187
 None
 0.63A 5kvaB-1woiA:
2.7		 5kvaB-1woiA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M66_C_ADNC502_1
(ADENOSYLHOMOCYSTEINA
SE)		 1woi AGMATINASE
(Deinococcus
radiodurans) 		5 / 12 THR A 178
GLN A 141
ASP A 231
LEU A 181
HIS A 145
 None
None
MN  A1502 (-2.0A)
None
MN  A1502 (-3.4A)
 1.35A 5m66C-1woiA:
undetectable		 5m66C-1woiA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M66_D_ADND502_1
(ADENOSYLHOMOCYSTEINA
SE)		 1woi AGMATINASE
(Deinococcus
radiodurans) 		5 / 12 THR A 178
GLN A 141
ASP A 231
LEU A 181
HIS A 145
 None
None
MN  A1502 (-2.0A)
None
MN  A1502 (-3.4A)
 1.40A 5m66D-1woiA:
2.4		 5m66D-1woiA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O4Y_D_CCSD14_0
(PHE-MAA-ASN-PRO-HIS-
LEU-SER-TRP-SER-TRP-
9KK-9KK-ARG-CCS-GLY-
NH2
PROGRAMMED CELL
DEATH 1 LIGAND 1)		 1woi AGMATINASE
(Deinococcus
radiodurans) 		5 / 12 PHE A 116
LEU A 272
SER A 124
GLY A 119
VAL A  36
 None
 1.31A 5o4yD-1woiA:
undetectable
5o4yE-1woiA:
undetectable		 5o4yD-1woiA:
5.99
5o4yE-1woiA:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UC1_A_486A801_1
(GLUCOCORTICOID
RECEPTOR)		 1woi AGMATINASE
(Deinococcus
radiodurans) 		5 / 12 LEU A 117
GLY A 118
GLY A 119
VAL A 123
LEU A 270
 None
 1.19A 5uc1A-1woiA:
undetectable		 5uc1A-1woiA:
13.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_A_PCFA1807_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 1woi AGMATINASE
(Deinococcus
radiodurans) 		5 / 7 LEU A 211
ILE A 257
GLY A 254
LEU A 249
ILE A 201
 None
 1.41A 5vkqA-1woiA:
undetectable
5vkqB-1woiA:
undetectable		 5vkqA-1woiA:
10.06
5vkqB-1woiA:
10.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XXI_A_LSNA501_2
(CYTOCHROME P450 2C9)		 1woi AGMATINASE
(Deinococcus
radiodurans) 		4 / 4 PHE A 233
LEU A 215
LEU A 258
VAL A 207
 None
 1.26A 5xxiA-1woiA:
undetectable		 5xxiA-1woiA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZVG_A_SAMA401_0
(389AA LONG
HYPOTHETICAL
NUCLEOLAR PROTEIN)		 1woi AGMATINASE
(Deinococcus
radiodurans) 		5 / 12 GLY A  25
ALA A 130
PRO A 114
TYR A 225
PHE A 131
 None
 1.29A 5zvgA-1woiA:
4.7		 5zvgA-1woiA:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNF_C_QPSC602_1
(-)		 1woi AGMATINASE
(Deinococcus
radiodurans) 		5 / 10 GLY A 269
LEU A 270
SER A 122
VAL A  31
CYH A 111
 None
 1.47A 6gnfC-1woiA:
2.6		 6gnfC-1woiA:
19.57