SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1woj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DMY_A_AZMA400_1
(MURINE CARBONIC
ANHYDRASE V)		 1woj 2',3'-CYCLIC-NUCLEOT
IDE
3'-PHOSPHODIESTERASE
(Homo
sapiens) 		5 / 11 HIS A 310
VAL A 280
LEU A 264
THR A 233
THR A 234
 HIS  A 310 (-1.0A)
VAL  A 280 ( 0.6A)
LEU  A 264 ( 0.6A)
THR  A 233 (-0.9A)
THR  A 234 ( 0.9A)
 1.32A 1dmyA-1wojA:
undetectable		 1dmyA-1wojA:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZAX_A_CAMA422_0
(CYTOCHROME P450-CAM)		 1woj 2',3'-CYCLIC-NUCLEOT
IDE
3'-PHOSPHODIESTERASE
(Homo
sapiens) 		4 / 7 LEU A 264
VAL A 370
THR A 175
VAL A 229
 LEU  A 264 ( 0.6A)
VAL  A 370 ( 0.6A)
THR  A 175 ( 0.9A)
VAL  A 229 ( 0.6A)
 1.02A 2zaxA-1wojA:
undetectable		 2zaxA-1wojA:
18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWG_B_CAMB420_0
(CAMPHOR
5-MONOOXYGENASE)		 1woj 2',3'-CYCLIC-NUCLEOT
IDE
3'-PHOSPHODIESTERASE
(Homo
sapiens) 		4 / 7 LEU A 264
VAL A 370
THR A 175
VAL A 229
 LEU  A 264 ( 0.6A)
VAL  A 370 ( 0.6A)
THR  A 175 ( 0.9A)
VAL  A 229 ( 0.6A)
 1.01A 3fwgB-1wojA:
undetectable		 3fwgB-1wojA:
17.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWI_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)		 1woj 2',3'-CYCLIC-NUCLEOT
IDE
3'-PHOSPHODIESTERASE
(Homo
sapiens) 		4 / 7 LEU A 264
VAL A 370
THR A 175
VAL A 229
 LEU  A 264 ( 0.6A)
VAL  A 370 ( 0.6A)
THR  A 175 ( 0.9A)
VAL  A 229 ( 0.6A)
 1.04A 3fwiA-1wojA:
undetectable		 3fwiA-1wojA:
17.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N62_B_ACTB860_0
(NITRIC OXIDE
SYNTHASE)		 1woj 2',3'-CYCLIC-NUCLEOT
IDE
3'-PHOSPHODIESTERASE
(Homo
sapiens) 		3 / 3 GLY A 194
TRP A 360
VAL A 271
 GLY  A 194 ( 0.0A)
TRP  A 360 ( 0.5A)
VAL  A 271 ( 0.6A)
 0.72A 3n62B-1wojA:
undetectable		 3n62B-1wojA:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N65_B_ACTB860_0
(NITRIC OXIDE
SYNTHASE)		 1woj 2',3'-CYCLIC-NUCLEOT
IDE
3'-PHOSPHODIESTERASE
(Homo
sapiens) 		3 / 3 GLY A 194
TRP A 360
VAL A 271
 GLY  A 194 ( 0.0A)
TRP  A 360 ( 0.5A)
VAL  A 271 ( 0.6A)
 0.67A 3n65B-1wojA:
undetectable		 3n65B-1wojA:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N66_B_ACTB860_0
(NITRIC OXIDE
SYNTHASE)		 1woj 2',3'-CYCLIC-NUCLEOT
IDE
3'-PHOSPHODIESTERASE
(Homo
sapiens) 		3 / 3 GLY A 194
TRP A 360
VAL A 271
 GLY  A 194 ( 0.0A)
TRP  A 360 ( 0.5A)
VAL  A 271 ( 0.6A)
 0.69A 3n66B-1wojA:
undetectable		 3n66B-1wojA:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SMT_A_ACTA500_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD3)		 1woj 2',3'-CYCLIC-NUCLEOT
IDE
3'-PHOSPHODIESTERASE
(Homo
sapiens) 		3 / 3 PHE A 262
SER A 283
GLN A 285
 PHE  A 262 ( 1.3A)
SER  A 283 ( 0.0A)
GLN  A 285 ( 0.6A)
 0.62A 3smtA-1wojA:
undetectable		 3smtA-1wojA:
18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1woj 2',3'-CYCLIC-NUCLEOT
IDE
3'-PHOSPHODIESTERASE
(Homo
sapiens) 		4 / 6 LEU A 347
PHE A 189
LEU A 193
PHE A 199
 LEU  A 347 ( 0.6A)
PHE  A 189 ( 1.3A)
LEU  A 193 ( 0.6A)
PHE  A 199 ( 1.3A)
 0.99A 3wg7P-1wojA:
undetectable
3wg7W-1wojA:
undetectable		 3wg7P-1wojA:
21.91
3wg7W-1wojA:
15.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IJI_F_BEZF501_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN YIBF)		 1woj 2',3'-CYCLIC-NUCLEOT
IDE
3'-PHOSPHODIESTERASE
(Homo
sapiens) 		4 / 8 ALA A 249
LEU A 166
TYR A 378
TYR A 258
 ALA  A 249 ( 0.0A)
LEU  A 166 ( 0.6A)
TYR  A 378 ( 1.3A)
TYR  A 258 ( 1.3A)
 1.16A 4ijiF-1wojA:
undetectable		 4ijiF-1wojA:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKV_A_AERA601_1
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 1woj 2',3'-CYCLIC-NUCLEOT
IDE
3'-PHOSPHODIESTERASE
(Homo
sapiens) 		5 / 12 LEU A 230
ALA A 278
ARG A 183
ALA A 185
VAL A 370
 LEU  A 230 ( 0.6A)
ALA  A 278 ( 0.0A)
ARG  A 183 ( 0.6A)
ALA  A 185 ( 0.0A)
VAL  A 370 ( 0.6A)
 1.04A 4nkvA-1wojA:
undetectable		 4nkvA-1wojA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUO_B_ACTB804_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1woj 2',3'-CYCLIC-NUCLEOT
IDE
3'-PHOSPHODIESTERASE
(Homo
sapiens) 		3 / 3 GLY A 194
TRP A 360
VAL A 271
 GLY  A 194 ( 0.0A)
TRP  A 360 ( 0.5A)
VAL  A 271 ( 0.6A)
 0.70A 5vuoB-1wojA:
undetectable		 5vuoB-1wojA:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_A_9F2A302_1
(BETA-LACTAMASE)		 1woj 2',3'-CYCLIC-NUCLEOT
IDE
3'-PHOSPHODIESTERASE
(Homo
sapiens) 		5 / 9 PRO A 167
TYR A 169
THR A 233
THR A 234
ASP A 252
 PRO  A 167 ( 1.1A)
TYR  A 169 ( 1.3A)
THR  A 233 (-0.9A)
THR  A 234 ( 0.9A)
ASP  A 252 ( 0.6A)
 1.36A 6b5yA-1wojA:
0.0
6b5yB-1wojA:
undetectable		 6b5yA-1wojA:
18.18
6b5yB-1wojA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_A_9F2A302_1
(BETA-LACTAMASE)		 1woj 2',3'-CYCLIC-NUCLEOT
IDE
3'-PHOSPHODIESTERASE
(Homo
sapiens) 		5 / 9 PRO A 167
TYR A 169
THR A 233
THR A 234
ASP A 252
 PRO  A 167 ( 1.1A)
TYR  A 169 ( 1.3A)
THR  A 233 (-0.9A)
THR  A 234 ( 0.9A)
ASP  A 252 ( 0.6A)
 1.36A 6b68A-1wojA:
0.0
6b68B-1wojA:
0.0		 6b68A-1wojA:
18.18
6b68B-1wojA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_C_9F2C302_1
(BETA-LACTAMASE)		 1woj 2',3'-CYCLIC-NUCLEOT
IDE
3'-PHOSPHODIESTERASE
(Homo
sapiens) 		5 / 10 PRO A 167
TYR A 169
THR A 233
THR A 234
ASP A 252
 PRO  A 167 ( 1.1A)
TYR  A 169 ( 1.3A)
THR  A 233 (-0.9A)
THR  A 234 ( 0.9A)
ASP  A 252 ( 0.6A)
 1.35A 6b68C-1wojA:
0.0
6b68D-1wojA:
0.0		 6b68C-1wojA:
18.18
6b68D-1wojA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_A_9F2A302_1
(BETA-LACTAMASE)		 1woj 2',3'-CYCLIC-NUCLEOT
IDE
3'-PHOSPHODIESTERASE
(Homo
sapiens) 		5 / 9 PRO A 167
TYR A 169
THR A 233
THR A 234
ASP A 252
 PRO  A 167 ( 1.1A)
TYR  A 169 ( 1.3A)
THR  A 233 (-0.9A)
THR  A 234 ( 0.9A)
ASP  A 252 ( 0.6A)
 1.33A 6b69A-1wojA:
0.0
6b69B-1wojA:
0.0		 6b69A-1wojA:
18.18
6b69B-1wojA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_C_9F2C302_1
(BETA-LACTAMASE)		 1woj 2',3'-CYCLIC-NUCLEOT
IDE
3'-PHOSPHODIESTERASE
(Homo
sapiens) 		5 / 9 PRO A 167
TYR A 169
THR A 233
THR A 234
ASP A 252
 PRO  A 167 ( 1.1A)
TYR  A 169 ( 1.3A)
THR  A 233 (-0.9A)
THR  A 234 ( 0.9A)
ASP  A 252 ( 0.6A)
 1.36A 6b69C-1wojA:
0.0
6b69D-1wojA:
0.0		 6b69C-1wojA:
18.18
6b69D-1wojA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_C_9F2C302_1
(BETA-LACTAMASE)		 1woj 2',3'-CYCLIC-NUCLEOT
IDE
3'-PHOSPHODIESTERASE
(Homo
sapiens) 		5 / 9 PRO A 167
TYR A 169
THR A 233
THR A 234
ASP A 252
 PRO  A 167 ( 1.1A)
TYR  A 169 ( 1.3A)
THR  A 233 (-0.9A)
THR  A 234 ( 0.9A)
ASP  A 252 ( 0.6A)
 1.38A 6b6aC-1wojA:
0.0
6b6aD-1wojA:
undetectable		 6b6aC-1wojA:
18.18
6b6aD-1wojA:
18.18