SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1wom'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

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	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1A8U_A_BEZA295_0 (CHLOROPEROXIDASE T)	1wom	SIGMA FACTOR SIGB REGULATION PROTEIN RSBQ (Bacillus subtilis)	5 / 10	GLY A 26 PHE A 27 SER A 96 PHE A 159 HIS A 247	PGO A 601 ( 3.7A) PGO A 609 (-4.9A) PGO A 601 (-2.5A) None PGO A 601 ( 4.7A)	0.84A	1a8uA-1womA: 32.1	1a8uA-1womA: 25.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1A8U_B_BEZB294_0 (CHLOROPEROXIDASE T)	1wom	SIGMA FACTOR SIGB REGULATION PROTEIN RSBQ (Bacillus subtilis)	5 / 10	GLY A 26 PHE A 27 SER A 96 PHE A 159 HIS A 247	PGO A 601 ( 3.7A) PGO A 609 (-4.9A) PGO A 601 (-2.5A) None PGO A 601 ( 4.7A)	0.86A	1a8uB-1womA: 32.4	1a8uB-1womA: 25.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1AV2_C_DVAC6_0 (GRAMICIDIN A)	1wom	SIGMA FACTOR SIGB REGULATION PROTEIN RSBQ (Bacillus subtilis)	3 / 3	ALA A 99 VAL A 93 TRP A 34	None	0.79A	1av2C-1womA: undetectable 1av2D-1womA: undetectable	1av2C-1womA: 18.33 1av2D-1womA: 18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1JNO_A_DVAA6_0 (GRAMICIDIN A)	1wom	SIGMA FACTOR SIGB REGULATION PROTEIN RSBQ (Bacillus subtilis)	3 / 3	ALA A 36 VAL A 33 TRP A 34	PGO A 604 ( 3.9A) PGO A 604 (-4.8A) None	0.82A	1jnoA-1womA: undetectable	1jnoA-1womA: 18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1JNO_B_DVAB6_0 (GRAMICIDIN A)	1wom	SIGMA FACTOR SIGB REGULATION PROTEIN RSBQ (Bacillus subtilis)	3 / 3	ALA A 36 VAL A 33 TRP A 34	PGO A 604 ( 3.9A) PGO A 604 (-4.8A) None	0.82A	1jnoB-1womA: undetectable	1jnoB-1womA: 18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1JO3_A_DVAA6_0 (GRAMICIDIN B)	1wom	SIGMA FACTOR SIGB REGULATION PROTEIN RSBQ (Bacillus subtilis)	3 / 3	ALA A 36 VAL A 33 TRP A 34	PGO A 604 ( 3.9A) PGO A 604 (-4.8A) None	0.91A	1jo3A-1womA: undetectable	1jo3A-1womA: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1JO3_B_DVAB6_0 (GRAMICIDIN B)	1wom	SIGMA FACTOR SIGB REGULATION PROTEIN RSBQ (Bacillus subtilis)	3 / 3	ALA A 36 VAL A 33 TRP A 34	PGO A 604 ( 3.9A) PGO A 604 (-4.8A) None	0.91A	1jo3B-1womA: undetectable	1jo3B-1womA: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1MAG_A_DVAA6_0 (GRAMICIDIN A)	1wom	SIGMA FACTOR SIGB REGULATION PROTEIN RSBQ (Bacillus subtilis)	3 / 3	ALA A 36 VAL A 33 TRP A 34	PGO A 604 ( 3.9A) PGO A 604 (-4.8A) None	0.92A	1magA-1womA: undetectable	1magA-1womA: 18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1MAG_B_DVAB6_0 (GRAMICIDIN A)	1wom	SIGMA FACTOR SIGB REGULATION PROTEIN RSBQ (Bacillus subtilis)	3 / 3	ALA A 36 VAL A 33 TRP A 34	PGO A 604 ( 3.9A) PGO A 604 (-4.8A) None	0.92A	1magB-1womA: undetectable	1magB-1womA: 18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1NG8_A_DVAA6_0 (GRAMICIDIN A)	1wom	SIGMA FACTOR SIGB REGULATION PROTEIN RSBQ (Bacillus subtilis)	3 / 3	ALA A 36 VAL A 33 TRP A 34	PGO A 604 ( 3.9A) PGO A 604 (-4.8A) None	0.85A	1ng8A-1womA: undetectable	1ng8A-1womA: 7.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1NG8_B_DVAB6_0 (GRAMICIDIN A)	1wom	SIGMA FACTOR SIGB REGULATION PROTEIN RSBQ (Bacillus subtilis)	3 / 3	ALA A 36 VAL A 33 TRP A 34	PGO A 604 ( 3.9A) PGO A 604 (-4.8A) None	0.85A	1ng8B-1womA: undetectable	1ng8B-1womA: 7.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1NRM_A_DVAA6_0 (GRAMICIDIN A)	1wom	SIGMA FACTOR SIGB REGULATION PROTEIN RSBQ (Bacillus subtilis)	3 / 3	ALA A 36 VAL A 33 TRP A 34	PGO A 604 ( 3.9A) PGO A 604 (-4.8A) None	0.89A	1nrmA-1womA: undetectable	1nrmA-1womA: 18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1NRM_A_DVAA6_0 (GRAMICIDIN A)	1wom	SIGMA FACTOR SIGB REGULATION PROTEIN RSBQ (Bacillus subtilis)	3 / 3	ALA A 99 VAL A 93 TRP A 34	None	0.88A	1nrmA-1womA: undetectable	1nrmA-1womA: 18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1NRM_B_DVAB6_0 (GRAMICIDIN A)	1wom	SIGMA FACTOR SIGB REGULATION PROTEIN RSBQ (Bacillus subtilis)	3 / 3	ALA A 36 VAL A 33 TRP A 34	PGO A 604 ( 3.9A) PGO A 604 (-4.8A) None	0.89A	1nrmB-1womA: undetectable	1nrmB-1womA: 18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1NRM_B_DVAB6_0 (GRAMICIDIN A)	1wom	SIGMA FACTOR SIGB REGULATION PROTEIN RSBQ (Bacillus subtilis)	3 / 3	ALA A 99 VAL A 93 TRP A 34	None	0.88A	1nrmB-1womA: undetectable	1nrmB-1womA: 18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1NRU_A_DVAA6_0 (GRAMICIDIN A)	1wom	SIGMA FACTOR SIGB REGULATION PROTEIN RSBQ (Bacillus subtilis)	3 / 3	ALA A 36 VAL A 33 TRP A 34	PGO A 604 ( 3.9A) PGO A 604 (-4.8A) None	0.89A	1nruA-1womA: undetectable	1nruA-1womA: 18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1NRU_B_DVAB6_0 (GRAMICIDIN A)	1wom	SIGMA FACTOR SIGB REGULATION PROTEIN RSBQ (Bacillus subtilis)	3 / 3	ALA A 36 VAL A 33 TRP A 34	PGO A 604 ( 3.9A) PGO A 604 (-4.8A) None	0.89A	1nruB-1womA: undetectable	1nruB-1womA: 18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1NT5_A_DVAA6_0 (GRAMICIDIN A)	1wom	SIGMA FACTOR SIGB REGULATION PROTEIN RSBQ (Bacillus subtilis)	3 / 3	ALA A 99 VAL A 93 TRP A 34	None	0.88A	1nt5A-1womA: undetectable	1nt5A-1womA: 8.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1NT5_B_DVAB6_0 (GRAMICIDIN A)	1wom	SIGMA FACTOR SIGB REGULATION PROTEIN RSBQ (Bacillus subtilis)	3 / 3	ALA A 99 VAL A 93 TRP A 34	None	0.88A	1nt5B-1womA: undetectable	1nt5B-1womA: 8.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1NT6_A_DVAA6_0 (GRAMICIDIN C)	1wom	SIGMA FACTOR SIGB REGULATION PROTEIN RSBQ (Bacillus subtilis)	3 / 3	ALA A 99 VAL A 93 TRP A 34	None	0.78A	1nt6A-1womA: undetectable	1nt6A-1womA: 4.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1NT6_B_DVAB6_0 (GRAMICIDIN C)	1wom	SIGMA FACTOR SIGB REGULATION PROTEIN RSBQ (Bacillus subtilis)	3 / 3	ALA A 99 VAL A 93 TRP A 34	None	0.78A	1nt6B-1womA: undetectable	1nt6B-1womA: 4.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1PG2_A_ADNA552_1 (METHIONYL-TRNA SYNTHETASE)	1wom	SIGMA FACTOR SIGB REGULATION PROTEIN RSBQ (Bacillus subtilis)	5 / 11	ALA A 24 HIS A 247 GLY A 120 HIS A 95 ILE A 101	None PGO A 601 ( 4.7A) None PGO A 601 ( 4.8A) None	1.01A	1pg2A-1womA: 2.3	1pg2A-1womA: 19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1W5U_C_DVAC6_0 (GRAMICIDIN D)	1wom	SIGMA FACTOR SIGB REGULATION PROTEIN RSBQ (Bacillus subtilis)	3 / 3	ALA A 99 VAL A 93 TRP A 34	None	0.81A	1w5uC-1womA: undetectable 1w5uD-1womA: undetectable	1w5uC-1womA: 18.33 1w5uD-1womA: 18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2FT9_A_CHDA130_0 (FATTY ACID-BINDING PROTEIN 2, LIVER)	1wom	SIGMA FACTOR SIGB REGULATION PROTEIN RSBQ (Bacillus subtilis)	5 / 12	PHE A 50 CYH A 82 VAL A 78 PHE A 113 LEU A 116	None	1.23A	2ft9A-1womA: undetectable	2ft9A-1womA: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2HA4_A_ACHA546_0 (ACETYLCHOLINESTERASE)	1wom	SIGMA FACTOR SIGB REGULATION PROTEIN RSBQ (Bacillus subtilis)	4 / 8	TYR A 52 TYR A 125 HIS A 95 GLY A 120	None None PGO A 601 ( 4.8A) None	1.11A	2ha4A-1womA: 11.4	2ha4A-1womA: 20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2HA4_B_ACHB603_0 (ACETYLCHOLINESTERASE)	1wom	SIGMA FACTOR SIGB REGULATION PROTEIN RSBQ (Bacillus subtilis)	4 / 7	TYR A 52 TYR A 125 HIS A 95 GLY A 120	None None PGO A 601 ( 4.8A) None	1.10A	2ha4B-1womA: 11.5	2ha4B-1womA: 20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2IZQ_B_DVAB6_0 (GRAMICIDIN D)	1wom	SIGMA FACTOR SIGB REGULATION PROTEIN RSBQ (Bacillus subtilis)	3 / 3	TRP A 34 ALA A 99 VAL A 93	None	0.78A	2izqA-1womA: undetectable 2izqB-1womA: undetectable	2izqA-1womA: 18.33 2izqB-1womA: 18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2KCE_A_D16A566_2 (THYMIDYLATE SYNTHASE)	1wom	SIGMA FACTOR SIGB REGULATION PROTEIN RSBQ (Bacillus subtilis)	3 / 3	HIS A 200 ILE A 107 LEU A 116	None	0.75A	2kceA-1womA: undetectable	2kceA-1womA: 20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2PNC_A_CLUA808_1 (COPPER AMINE OXIDASE, LIVER ISOZYME)	1wom	SIGMA FACTOR SIGB REGULATION PROTEIN RSBQ (Bacillus subtilis)	4 / 7	ALA A 222 TYR A 125 MET A 118 HIS A 247	None None None PGO A 601 ( 4.7A)	1.48A	2pncA-1womA: undetectable	2pncA-1womA: 16.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AQI_B_CHDB6_0 (FERROCHELATASE)	1wom	SIGMA FACTOR SIGB REGULATION PROTEIN RSBQ (Bacillus subtilis)	5 / 12	MET A 251 LEU A 176 PHE A 180 ILE A 221 SER A 32	PGO A 604 (-4.6A) None None None None	1.29A	3aqiB-1womA: 0.0	3aqiB-1womA: 20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3L8L_A_DVAA6_0 (GRAMICIDIN D)	1wom	SIGMA FACTOR SIGB REGULATION PROTEIN RSBQ (Bacillus subtilis)	3 / 3	ALA A 99 VAL A 93 TRP A 34	None	0.80A	3l8lA-1womA: undetectable 3l8lB-1womA: undetectable	3l8lA-1womA: 18.33 3l8lB-1womA: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3L8L_C_DVAC6_0 (GRAMICIDIN D)	1wom	SIGMA FACTOR SIGB REGULATION PROTEIN RSBQ (Bacillus subtilis)	3 / 3	ALA A 99 VAL A 93 TRP A 34	None	0.80A	3l8lC-1womA: undetectable 3l8lD-1womA: undetectable	3l8lC-1womA: 18.33 3l8lD-1womA: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3UA1_A_08YA600_1 (CYTOCHROME P450 3A4)	1wom	SIGMA FACTOR SIGB REGULATION PROTEIN RSBQ (Bacillus subtilis)	5 / 12	ARG A 179 SER A 96 PHE A 180 PHE A 196 ALA A 195	PGO A 604 (-4.5A) PGO A 601 (-2.5A) None None None	1.33A	3ua1A-1womA: 0.0	3ua1A-1womA: 20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4UCK_A_SAMA2409_1 (RNA-DIRECTED RNA POLYMERASE L)	1wom	SIGMA FACTOR SIGB REGULATION PROTEIN RSBQ (Bacillus subtilis)	3 / 3	SER A 198 ASP A 64 ASP A 72	None	0.81A	4uckA-1womA: undetectable	4uckA-1womA: 20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4ZDZ_A_TPFA602_1 (LANOSTEROL 14-ALPHA DEMETHYLASE)	1wom	SIGMA FACTOR SIGB REGULATION PROTEIN RSBQ (Bacillus subtilis)	4 / 7	PHE A 41 ILE A 21 GLY A 262 LEU A 214	None	0.87A	4zdzA-1womA: undetectable	4zdzA-1womA: 19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4ZE3_A_TPFA602_1 (LANOSTEROL 14-ALPHA DEMETHYLASE)	1wom	SIGMA FACTOR SIGB REGULATION PROTEIN RSBQ (Bacillus subtilis)	4 / 7	PHE A 41 ILE A 21 GLY A 262 LEU A 214	None	0.78A	4ze3A-1womA: undetectable	4ze3A-1womA: 19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4ZJZ_A_BEZA1001_0 (BENZOATE-COENZYME A LIGASE)	1wom	SIGMA FACTOR SIGB REGULATION PROTEIN RSBQ (Bacillus subtilis)	4 / 8	ALA A 24 VAL A 78 PHE A 92 GLY A 94	None	0.55A	4zjzA-1womA: 3.9	4zjzA-1womA: 19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5E4D_B_BEZB201_0 (HYDROXYNITRILE LYASE)	1wom	SIGMA FACTOR SIGB REGULATION PROTEIN RSBQ (Bacillus subtilis)	5 / 11	VAL A 91 VAL A 117 VAL A 93 PHE A 23 LEU A 265	None None None None PGO A 611 (-4.4A)	1.10A	5e4dB-1womA: undetectable	5e4dB-1womA: 20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ESE_A_TPFA602_1 (LANOSTEROL 14-ALPHA DEMETHYLASE)	1wom	SIGMA FACTOR SIGB REGULATION PROTEIN RSBQ (Bacillus subtilis)	4 / 8	PHE A 41 ILE A 21 GLY A 262 LEU A 214	None	0.84A	5eseA-1womA: undetectable	5eseA-1womA: 19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ESF_A_TPFA602_1 (LANOSTEROL 14-ALPHA DEMETHYLASE)	1wom	SIGMA FACTOR SIGB REGULATION PROTEIN RSBQ (Bacillus subtilis)	4 / 8	PHE A 41 ILE A 21 GLY A 262 LEU A 214	None	0.85A	5esfA-1womA: undetectable	5esfA-1womA: 19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ESJ_A_TPFA602_1 (LANOSTEROL 14-ALPHA DEMETHYLASE)	1wom	SIGMA FACTOR SIGB REGULATION PROTEIN RSBQ (Bacillus subtilis)	4 / 8	PHE A 41 ILE A 21 GLY A 262 LEU A 214	None	0.80A	5esjA-1womA: undetectable	5esjA-1womA: 19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ESM_A_TPFA602_1 (LANOSTEROL 14-ALPHA DEMETHYLASE)	1wom	SIGMA FACTOR SIGB REGULATION PROTEIN RSBQ (Bacillus subtilis)	4 / 7	PHE A 41 ILE A 21 GLY A 262 LEU A 214	None	0.86A	5esmA-1womA: undetectable	5esmA-1womA: 19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5UC1_A_486A801_2 (GLUCOCORTICOID RECEPTOR)	1wom	SIGMA FACTOR SIGB REGULATION PROTEIN RSBQ (Bacillus subtilis)	3 / 3	TRP A 155 MET A 147 ASN A 151	None PGO A 612 ( 4.2A) None	1.45A	5uc1B-1womA: undetectable	5uc1B-1womA: 13.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5WWS_A_SAMA501_0 (PUTATIVE METHYLTRANSFERASE NSUN6)	1wom	SIGMA FACTOR SIGB REGULATION PROTEIN RSBQ (Bacillus subtilis)	5 / 12	ALA A 222 PRO A 223 GLY A 134 GLY A 26 LEU A 176	None None None PGO A 601 ( 3.7A) None	0.93A	5wwsA-1womA: undetectable	5wwsA-1womA: 21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5WWS_A_SAMA501_0 (PUTATIVE METHYLTRANSFERASE NSUN6)	1wom	SIGMA FACTOR SIGB REGULATION PROTEIN RSBQ (Bacillus subtilis)	5 / 12	ALA A 222 PRO A 223 GLY A 135 GLY A 26 LEU A 176	None None None PGO A 601 ( 3.7A) None	1.06A	5wwsA-1womA: undetectable	5wwsA-1womA: 21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5Z84_J_CHDJ101_0 (CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	1wom	SIGMA FACTOR SIGB REGULATION PROTEIN RSBQ (Bacillus subtilis)	3 / 3	TYR A 74 ARG A 67 THR A 70	None	0.92A	5z84J-1womA: undetectable	5z84J-1womA: 11.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	6AP6_A_TLFA300_0 (PROBABLE STRIGOLACTONE ESTERASE DAD2)	1wom	SIGMA FACTOR SIGB REGULATION PROTEIN RSBQ (Bacillus subtilis)	5 / 12	VAL A 33 PHE A 41 ILE A 21 VAL A 91 PHE A 23	PGO A 604 (-4.8A) None None None None	1.36A	6ap6A-1womA: 39.6	6ap6A-1womA: 38.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	6AP6_B_TLFB300_0 (PROBABLE STRIGOLACTONE ESTERASE DAD2)	1wom	SIGMA FACTOR SIGB REGULATION PROTEIN RSBQ (Bacillus subtilis)	5 / 12	VAL A 33 PHE A 41 ILE A 21 VAL A 91 PHE A 23	PGO A 604 (-4.8A) None None None None	1.36A	6ap6B-1womA: 39.6	6ap6B-1womA: 38.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6B5V_B_ECLB1001_1 (TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL SUBFAMILY V MEMBER 5)	1wom	SIGMA FACTOR SIGB REGULATION PROTEIN RSBQ (Bacillus subtilis)	4 / 7	PHE A 50 ILE A 48 CYH A 82 ILE A 101	None	0.86A	6b5vA-1womA: undetectable 6b5vB-1womA: undetectable	6b5vA-1womA: 14.73 6b5vB-1womA: 14.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6F32_B_ACTB602_0 (AMINE OXIDASE LKCE)	1wom	SIGMA FACTOR SIGB REGULATION PROTEIN RSBQ (Bacillus subtilis)	4 / 6	ASN A 127 TYR A 133 VAL A 226 THR A 225	None	1.37A	6f32B-1womA: undetectable	6f32B-1womA: 21.88

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1A8U_A_BEZA295_0","CHLOROPEROXIDASE T","1wom","SIGMA FACTOR SIGB REGULATION PROTEIN RSBQ","Bacillus subtilis",5,"GLY A  26;PHE A  27;SER A  96;PHE A 159;HIS A 247","PGO A 601 ( 3.7A);PGO A 609 (-4.9A);PGO A 601 (-2.5A);None;PGO A 601 ( 4.7A)","0.84A","1a8uA-1womA:32.1","1a8uA-1womA:25.60"],["1A8U_B_BEZB294_0","CHLOROPEROXIDASE T","1wom","SIGMA FACTOR SIGB REGULATION PROTEIN RSBQ","Bacillus subtilis",5,"GLY A  26;PHE A  27;SER A  96;PHE A 159;HIS A 247","PGO A 601 ( 3.7A);PGO A 609 (-4.9A);PGO A 601 (-2.5A);None;PGO A 601 ( 4.7A)","0.86A","1a8uB-1womA:32.4","1a8uB-1womA:25.60"],["1AV2_C_DVAC6_0","GRAMICIDIN A","1wom","SIGMA FACTOR SIGB REGULATION PROTEIN RSBQ","Bacillus subtilis",3,"ALA A  99;VAL A  93;TRP A  34","None","0.79A","1av2C-1womA:undetectable;1av2D-1womA:undetectable","1av2C-1womA:18.33;1av2D-1womA:18.33"],["1JNO_A_DVAA6_0","GRAMICIDIN A","1wom","SIGMA FACTOR SIGB REGULATION PROTEIN RSBQ","Bacillus subtilis",3,"ALA A  36;VAL A  33;TRP A  34","PGO A 604 ( 3.9A);PGO A 604 (-4.8A);None","0.82A","1jnoA-1womA:undetectable","1jnoA-1womA:18.33"],["1JNO_B_DVAB6_0","GRAMICIDIN A","1wom","SIGMA FACTOR SIGB REGULATION PROTEIN RSBQ","Bacillus subtilis",3,"ALA A  36;VAL A  33;TRP A  34","PGO A 604 ( 3.9A);PGO A 604 (-4.8A);None","0.82A","1jnoB-1womA:undetectable","1jnoB-1womA:18.33"],["1JO3_A_DVAA6_0","GRAMICIDIN B","1wom","SIGMA FACTOR SIGB REGULATION PROTEIN RSBQ","Bacillus subtilis",3,"ALA A  36;VAL A  33;TRP A  34","PGO A 604 ( 3.9A);PGO A 604 (-4.8A);None","0.91A","1jo3A-1womA:undetectable","1jo3A-1womA:20.00"],["1JO3_B_DVAB6_0","GRAMICIDIN B","1wom","SIGMA FACTOR SIGB REGULATION PROTEIN RSBQ","Bacillus subtilis",3,"ALA A  36;VAL A  33;TRP A  34","PGO A 604 ( 3.9A);PGO A 604 (-4.8A);None","0.91A","1jo3B-1womA:undetectable","1jo3B-1womA:20.00"],["1MAG_A_DVAA6_0","GRAMICIDIN A","1wom","SIGMA FACTOR SIGB REGULATION PROTEIN RSBQ","Bacillus subtilis",3,"ALA A  36;VAL A  33;TRP A  34","PGO A 604 ( 3.9A);PGO A 604 (-4.8A);None","0.92A","1magA-1womA:undetectable","1magA-1womA:18.33"],["1MAG_B_DVAB6_0","GRAMICIDIN A","1wom","SIGMA FACTOR SIGB REGULATION PROTEIN RSBQ","Bacillus subtilis",3,"ALA A  36;VAL A  33;TRP A  34","PGO A 604 ( 3.9A);PGO A 604 (-4.8A);None","0.92A","1magB-1womA:undetectable","1magB-1womA:18.33"],["1NG8_A_DVAA6_0","GRAMICIDIN A","1wom","SIGMA FACTOR SIGB REGULATION PROTEIN RSBQ","Bacillus subtilis",3,"ALA A  36;VAL A  33;TRP A  34","PGO A 604 ( 3.9A);PGO A 604 (-4.8A);None","0.85A","1ng8A-1womA:undetectable","1ng8A-1womA:7.19"],["1NG8_B_DVAB6_0","GRAMICIDIN A","1wom","SIGMA FACTOR SIGB REGULATION PROTEIN RSBQ","Bacillus subtilis",3,"ALA A  36;VAL A  33;TRP A  34","PGO A 604 ( 3.9A);PGO A 604 (-4.8A);None","0.85A","1ng8B-1womA:undetectable","1ng8B-1womA:7.19"],["1NRM_A_DVAA6_0","GRAMICIDIN A","1wom","SIGMA FACTOR SIGB REGULATION PROTEIN RSBQ","Bacillus subtilis",3,"ALA A  36;VAL A  33;TRP A  34","PGO A 604 ( 3.9A);PGO A 604 (-4.8A);None","0.89A","1nrmA-1womA:undetectable","1nrmA-1womA:18.33"],["1NRM_A_DVAA6_0","GRAMICIDIN A","1wom","SIGMA FACTOR SIGB REGULATION PROTEIN RSBQ","Bacillus subtilis",3,"ALA A  99;VAL A  93;TRP A  34","None","0.88A","1nrmA-1womA:undetectable","1nrmA-1womA:18.33"],["1NRM_B_DVAB6_0","GRAMICIDIN A","1wom","SIGMA FACTOR SIGB REGULATION PROTEIN RSBQ","Bacillus subtilis",3,"ALA A  36;VAL A  33;TRP A  34","PGO A 604 ( 3.9A);PGO A 604 (-4.8A);None","0.89A","1nrmB-1womA:undetectable","1nrmB-1womA:18.33"],["1NRM_B_DVAB6_0","GRAMICIDIN A","1wom","SIGMA FACTOR SIGB REGULATION PROTEIN RSBQ","Bacillus subtilis",3,"ALA A  99;VAL A  93;TRP A  34","None","0.88A","1nrmB-1womA:undetectable","1nrmB-1womA:18.33"],["1NRU_A_DVAA6_0","GRAMICIDIN A","1wom","SIGMA FACTOR SIGB REGULATION PROTEIN RSBQ","Bacillus subtilis",3,"ALA A  36;VAL A  33;TRP A  34","PGO A 604 ( 3.9A);PGO A 604 (-4.8A);None","0.89A","1nruA-1womA:undetectable","1nruA-1womA:18.33"],["1NRU_B_DVAB6_0","GRAMICIDIN A","1wom","SIGMA FACTOR SIGB REGULATION PROTEIN RSBQ","Bacillus subtilis",3,"ALA A  36;VAL A  33;TRP A  34","PGO A 604 ( 3.9A);PGO A 604 (-4.8A);None","0.89A","1nruB-1womA:undetectable","1nruB-1womA:18.33"],["1NT5_A_DVAA6_0","GRAMICIDIN A","1wom","SIGMA FACTOR SIGB REGULATION PROTEIN RSBQ","Bacillus subtilis",3,"ALA A  99;VAL A  93;TRP A  34","None","0.88A","1nt5A-1womA:undetectable","1nt5A-1womA:8.21"],["1NT5_B_DVAB6_0","GRAMICIDIN A","1wom","SIGMA FACTOR SIGB REGULATION PROTEIN RSBQ","Bacillus subtilis",3,"ALA A  99;VAL A  93;TRP A  34","None","0.88A","1nt5B-1womA:undetectable","1nt5B-1womA:8.21"],["1NT6_A_DVAA6_0","GRAMICIDIN C","1wom","SIGMA FACTOR SIGB REGULATION PROTEIN RSBQ","Bacillus subtilis",3,"ALA A  99;VAL A  93;TRP A  34","None","0.78A","1nt6A-1womA:undetectable","1nt6A-1womA:4.45"],["1NT6_B_DVAB6_0","GRAMICIDIN C","1wom","SIGMA FACTOR SIGB REGULATION PROTEIN RSBQ","Bacillus subtilis",3,"ALA A  99;VAL A  93;TRP A  34","None","0.78A","1nt6B-1womA:undetectable","1nt6B-1womA:4.45"],["1PG2_A_ADNA552_1","METHIONYL-TRNA SYNTHETASE","1wom","SIGMA FACTOR SIGB REGULATION PROTEIN RSBQ","Bacillus subtilis",5,"ALA A  24;HIS A 247;GLY A 120;HIS A  95;ILE A 101","None;PGO A 601 ( 4.7A);None;PGO A 601 ( 4.8A);None","1.01A","1pg2A-1womA:2.3","1pg2A-1womA:19.64"],["1W5U_C_DVAC6_0","GRAMICIDIN D","1wom","SIGMA FACTOR SIGB REGULATION PROTEIN RSBQ","Bacillus subtilis",3,"ALA A  99;VAL A  93;TRP A  34","None","0.81A","1w5uC-1womA:undetectable;1w5uD-1womA:undetectable","1w5uC-1womA:18.33;1w5uD-1womA:18.33"],["2FT9_A_CHDA130_0","FATTY ACID-BINDING PROTEIN 2, LIVER","1wom","SIGMA FACTOR SIGB REGULATION PROTEIN RSBQ","Bacillus subtilis",5,"PHE A  50;CYH A  82;VAL A  78;PHE A 113;LEU A 116","None","1.23A","2ft9A-1womA:undetectable","2ft9A-1womA:20.00"],["2HA4_A_ACHA546_0","ACETYLCHOLINESTERASE","1wom","SIGMA FACTOR SIGB REGULATION PROTEIN RSBQ","Bacillus subtilis",4,"TYR A  52;TYR A 125;HIS A  95;GLY A 120","None;None;PGO A 601 ( 4.8A);None","1.11A","2ha4A-1womA:11.4","2ha4A-1womA:20.55"],["2HA4_B_ACHB603_0","ACETYLCHOLINESTERASE","1wom","SIGMA FACTOR SIGB REGULATION PROTEIN RSBQ","Bacillus subtilis",4,"TYR A  52;TYR A 125;HIS A  95;GLY A 120","None;None;PGO A 601 ( 4.8A);None","1.10A","2ha4B-1womA:11.5","2ha4B-1womA:20.55"],["2IZQ_B_DVAB6_0","GRAMICIDIN D","1wom","SIGMA FACTOR SIGB REGULATION PROTEIN RSBQ","Bacillus subtilis",3,"TRP A  34;ALA A  99;VAL A  93","None","0.78A","2izqA-1womA:undetectable;2izqB-1womA:undetectable","2izqA-1womA:18.33;2izqB-1womA:18.33"],["2KCE_A_D16A566_2","THYMIDYLATE SYNTHASE","1wom","SIGMA FACTOR SIGB REGULATION PROTEIN RSBQ","Bacillus subtilis",3,"HIS A 200;ILE A 107;LEU A 116","None","0.75A","2kceA-1womA:undetectable","2kceA-1womA:20.74"],["2PNC_A_CLUA808_1","COPPER AMINE OXIDASE, LIVER ISOZYME","1wom","SIGMA FACTOR SIGB REGULATION PROTEIN RSBQ","Bacillus subtilis",4,"ALA A 222;TYR A 125;MET A 118;HIS A 247","None;None;None;PGO A 601 ( 4.7A)","1.48A","2pncA-1womA:undetectable","2pncA-1womA:16.51"],["3AQI_B_CHDB6_0","FERROCHELATASE","1wom","SIGMA FACTOR SIGB REGULATION PROTEIN RSBQ","Bacillus subtilis",5,"MET A 251;LEU A 176;PHE A 180;ILE A 221;SER A  32","PGO A 604 (-4.6A);None;None;None;None","1.29A","3aqiB-1womA:0.0","3aqiB-1womA:20.94"],["3L8L_A_DVAA6_0","GRAMICIDIN D","1wom","SIGMA FACTOR SIGB REGULATION PROTEIN RSBQ","Bacillus subtilis",3,"ALA A  99;VAL A  93;TRP A  34","None","0.80A","3l8lA-1womA:undetectable;3l8lB-1womA:undetectable","3l8lA-1womA:18.33;3l8lB-1womA:20.00"],["3L8L_C_DVAC6_0","GRAMICIDIN D","1wom","SIGMA FACTOR SIGB REGULATION PROTEIN RSBQ","Bacillus subtilis",3,"ALA A  99;VAL A  93;TRP A  34","None","0.80A","3l8lC-1womA:undetectable;3l8lD-1womA:undetectable","3l8lC-1womA:18.33;3l8lD-1womA:20.00"],["3UA1_A_08YA600_1","CYTOCHROME P450 3A4","1wom","SIGMA FACTOR SIGB REGULATION PROTEIN RSBQ","Bacillus subtilis",5,"ARG A 179;SER A  96;PHE A 180;PHE A 196;ALA A 195","PGO A 604 (-4.5A);PGO A 601 (-2.5A);None;None;None","1.33A","3ua1A-1womA:0.0","3ua1A-1womA:20.08"],["4UCK_A_SAMA2409_1","RNA-DIRECTED RNA POLYMERASE L","1wom","SIGMA FACTOR SIGB REGULATION PROTEIN RSBQ","Bacillus subtilis",3,"SER A 198;ASP A  64;ASP A  72","None","0.81A","4uckA-1womA:undetectable","4uckA-1womA:20.47"],["4ZDZ_A_TPFA602_1","LANOSTEROL 14-ALPHA DEMETHYLASE","1wom","SIGMA FACTOR SIGB REGULATION PROTEIN RSBQ","Bacillus subtilis",4,"PHE A  41;ILE A  21;GLY A 262;LEU A 214","None","0.87A","4zdzA-1womA:undetectable","4zdzA-1womA:19.37"],["4ZE3_A_TPFA602_1","LANOSTEROL 14-ALPHA DEMETHYLASE","1wom","SIGMA FACTOR SIGB REGULATION PROTEIN RSBQ","Bacillus subtilis",4,"PHE A  41;ILE A  21;GLY A 262;LEU A 214","None","0.78A","4ze3A-1womA:undetectable","4ze3A-1womA:19.37"],["4ZJZ_A_BEZA1001_0","BENZOATE-COENZYME A LIGASE","1wom","SIGMA FACTOR SIGB REGULATION PROTEIN RSBQ","Bacillus subtilis",4,"ALA A  24;VAL A  78;PHE A  92;GLY A  94","None","0.55A","4zjzA-1womA:3.9","4zjzA-1womA:19.43"],["5E4D_B_BEZB201_0","HYDROXYNITRILE LYASE","1wom","SIGMA FACTOR SIGB REGULATION PROTEIN RSBQ","Bacillus subtilis",5,"VAL A  91;VAL A 117;VAL A  93;PHE A  23;LEU A 265","None;None;None;None;PGO A 611 (-4.4A)","1.10A","5e4dB-1womA:undetectable","5e4dB-1womA:20.44"],["5ESE_A_TPFA602_1","LANOSTEROL 14-ALPHA DEMETHYLASE","1wom","SIGMA FACTOR SIGB REGULATION PROTEIN RSBQ","Bacillus subtilis",4,"PHE A  41;ILE A  21;GLY A 262;LEU A 214","None","0.84A","5eseA-1womA:undetectable","5eseA-1womA:19.37"],["5ESF_A_TPFA602_1","LANOSTEROL 14-ALPHA DEMETHYLASE","1wom","SIGMA FACTOR SIGB REGULATION PROTEIN RSBQ","Bacillus subtilis",4,"PHE A  41;ILE A  21;GLY A 262;LEU A 214","None","0.85A","5esfA-1womA:undetectable","5esfA-1womA:19.37"],["5ESJ_A_TPFA602_1","LANOSTEROL 14-ALPHA DEMETHYLASE","1wom","SIGMA FACTOR SIGB REGULATION PROTEIN RSBQ","Bacillus subtilis",4,"PHE A  41;ILE A  21;GLY A 262;LEU A 214","None","0.80A","5esjA-1womA:undetectable","5esjA-1womA:19.37"],["5ESM_A_TPFA602_1","LANOSTEROL 14-ALPHA DEMETHYLASE","1wom","SIGMA FACTOR SIGB REGULATION PROTEIN RSBQ","Bacillus subtilis",4,"PHE A  41;ILE A  21;GLY A 262;LEU A 214","None","0.86A","5esmA-1womA:undetectable","5esmA-1womA:19.19"],["5UC1_A_486A801_2","GLUCOCORTICOID RECEPTOR;GLUCOCORTICOID RECEPTOR","1wom","SIGMA FACTOR SIGB REGULATION PROTEIN RSBQ","Bacillus subtilis",3,"TRP A 155;MET A 147;ASN A 151","None;PGO A 612 ( 4.2A);None","1.45A","5uc1B-1womA:undetectable","5uc1B-1womA:13.70"],["5WWS_A_SAMA501_0","PUTATIVE METHYLTRANSFERASE NSUN6","1wom","SIGMA FACTOR SIGB REGULATION PROTEIN RSBQ","Bacillus subtilis",5,"ALA A 222;PRO A 223;GLY A 134;GLY A  26;LEU A 176","None;None;None;PGO A 601 ( 3.7A);None","0.93A","5wwsA-1womA:undetectable","5wwsA-1womA:21.38"],["5WWS_A_SAMA501_0","PUTATIVE METHYLTRANSFERASE NSUN6","1wom","SIGMA FACTOR SIGB REGULATION PROTEIN RSBQ","Bacillus subtilis",5,"ALA A 222;PRO A 223;GLY A 135;GLY A  26;LEU A 176","None;None;None;PGO A 601 ( 3.7A);None","1.06A","5wwsA-1womA:undetectable","5wwsA-1womA:21.38"],["5Z84_J_CHDJ101_0","CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","1wom","SIGMA FACTOR SIGB REGULATION PROTEIN RSBQ","Bacillus subtilis",3,"TYR A  74;ARG A  67;THR A  70","None","0.92A","5z84J-1womA:undetectable","5z84J-1womA:11.19"],["6AP6_A_TLFA300_0","PROBABLE STRIGOLACTONE ESTERASE DAD2","1wom","SIGMA FACTOR SIGB REGULATION PROTEIN RSBQ","Bacillus subtilis",5,"VAL A  33;PHE A  41;ILE A  21;VAL A  91;PHE A  23","PGO A 604 (-4.8A);None;None;None;None","1.36A","6ap6A-1womA:39.6","6ap6A-1womA:38.97"],["6AP6_B_TLFB300_0","PROBABLE STRIGOLACTONE ESTERASE DAD2","1wom","SIGMA FACTOR SIGB REGULATION PROTEIN RSBQ","Bacillus subtilis",5,"VAL A  33;PHE A  41;ILE A  21;VAL A  91;PHE A  23","PGO A 604 (-4.8A);None;None;None;None","1.36A","6ap6B-1womA:39.6","6ap6B-1womA:38.97"],["6B5V_B_ECLB1001_1","TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL SUBFAMILY V MEMBER 5;TRANSIENT RECEPTOR POTENTIAL CATION CHANNEL SUBFAMILY V MEMBER 5","1wom","SIGMA FACTOR SIGB REGULATION PROTEIN RSBQ","Bacillus subtilis",4,"PHE A  50;ILE A  48;CYH A  82;ILE A 101","None","0.86A","6b5vA-1womA:undetectable;6b5vB-1womA:undetectable","6b5vA-1womA:14.73;6b5vB-1womA:14.73"],["6F32_B_ACTB602_0","AMINE OXIDASE LKCE","1wom","SIGMA FACTOR SIGB REGULATION PROTEIN RSBQ","Bacillus subtilis",4,"ASN A 127;TYR A 133;VAL A 226;THR A 225","None","1.37A","6f32B-1womA:undetectable","6f32B-1womA:21.88"]]