SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1woq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K6C_B_MK1B902_1
(POL POLYPROTEIN)
1woq INORGANIC
POLYPHOSPHATE/ATP-GL
UCOMANNOKINASE

(Arthrobacter
sp.
KM)
5 / 10 ALA A 256
VAL A  78
ILE A  17
GLY A  26
GLY A  27
None
1.09A 1k6cA-1woqA:
undetectable
1k6cA-1woqA:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MRG_A_ADNA300_1
(ALPHA-MOMORCHARIN)
1woq INORGANIC
POLYPHOSPHATE/ATP-GL
UCOMANNOKINASE

(Arthrobacter
sp.
KM)
5 / 9 ILE A  15
GLY A  26
ILE A  28
ALA A  71
GLU A  70
None
1.11A 1mrgA-1woqA:
undetectable
1mrgA-1woqA:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N49_B_RITB301_1
(PROTEASE)
1woq INORGANIC
POLYPHOSPHATE/ATP-GL
UCOMANNOKINASE

(Arthrobacter
sp.
KM)
4 / 7 ASN A 122
GLY A 152
ILE A 153
ALA A 127
BGC  A 290 (-3.2A)
BGC  A 290 ( 3.7A)
None
None
0.72A 1n49A-1woqA:
undetectable
1n49A-1woqA:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IDW_B_017B401_1
(PROTEASE)
1woq INORGANIC
POLYPHOSPHATE/ATP-GL
UCOMANNOKINASE

(Arthrobacter
sp.
KM)
5 / 11 LEU A 163
VAL A 144
GLY A 135
ALA A 156
ILE A 158
None
0.76A 2idwA-1woqA:
undetectable
2idwA-1woqA:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NMZ_B_ROCB401_1
(PROTEASE)
1woq INORGANIC
POLYPHOSPHATE/ATP-GL
UCOMANNOKINASE

(Arthrobacter
sp.
KM)
6 / 12 LEU A 246
GLY A 254
ALA A 126
ASP A 123
ILE A 158
ALA A 244
None
None
None
BGC  A 290 (-2.9A)
None
None
1.32A 2nmzA-1woqA:
undetectable
2nmzA-1woqA:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NMZ_B_ROCB401_3
(PROTEASE)
1woq INORGANIC
POLYPHOSPHATE/ATP-GL
UCOMANNOKINASE

(Arthrobacter
sp.
KM)
6 / 12 LEU A 246
GLY A 254
ALA A 126
ASP A 123
ILE A 158
ALA A 244
None
None
None
BGC  A 290 (-2.9A)
None
None
1.32A 2nmzB-1woqA:
undetectable
2nmzB-1woqA:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W3A_A_TOPA1190_1
(DIHYDROFOLATE
REDUCTASE)
1woq INORGANIC
POLYPHOSPHATE/ATP-GL
UCOMANNOKINASE

(Arthrobacter
sp.
KM)
5 / 11 ILE A 241
GLU A 210
PHE A 206
ILE A 153
VAL A 220
None
1.04A 2w3aA-1woqA:
undetectable
2w3aA-1woqA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DCM_X_SAMX5452_0
(UNCHARACTERIZED
PROTEIN TM_1570)
1woq INORGANIC
POLYPHOSPHATE/ATP-GL
UCOMANNOKINASE

(Arthrobacter
sp.
KM)
6 / 11 THR A 148
ALA A 244
GLY A 223
LEU A 246
ARG A  40
ALA A 250
None
1.07A 3dcmX-1woqA:
undetectable
3dcmX-1woqA:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKP_B_478B200_2
(PROTEASE)
1woq INORGANIC
POLYPHOSPHATE/ATP-GL
UCOMANNOKINASE

(Arthrobacter
sp.
KM)
5 / 10 LEU A 163
VAL A 144
GLY A 135
ALA A 156
ILE A 158
None
0.86A 3ekpB-1woqA:
undetectable
3ekpB-1woqA:
17.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKP_C_478C200_1
(PROTEASE)
1woq INORGANIC
POLYPHOSPHATE/ATP-GL
UCOMANNOKINASE

(Arthrobacter
sp.
KM)
5 / 10 LEU A 163
VAL A 144
GLY A 135
ALA A 156
ILE A 158
None
0.96A 3ekpC-1woqA:
undetectable
3ekpC-1woqA:
17.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL0_A_1UNA201_2
(PROTEASE)
1woq INORGANIC
POLYPHOSPHATE/ATP-GL
UCOMANNOKINASE

(Arthrobacter
sp.
KM)
5 / 9 LEU A 163
VAL A 144
GLY A 135
ALA A 156
ILE A 158
None
0.79A 3el0B-1woqA:
undetectable
3el0B-1woqA:
17.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL4_A_ROCA100_2
(PROTEASE)
1woq INORGANIC
POLYPHOSPHATE/ATP-GL
UCOMANNOKINASE

(Arthrobacter
sp.
KM)
5 / 9 ASP A 123
ALA A 124
ILE A 147
GLY A 221
THR A 151
BGC  A 290 (-2.9A)
BGC  A 290 ( 3.7A)
None
None
PO4  A 280 (-3.5A)
1.10A 3el4B-1woqA:
undetectable
3el4B-1woqA:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB3_A_SAMA1102_0
(STRUCTURAL PROTEIN
VP3)
1woq INORGANIC
POLYPHOSPHATE/ATP-GL
UCOMANNOKINASE

(Arthrobacter
sp.
KM)
5 / 12 TYR A 205
GLY A 152
ALA A 179
ALA A  95
PRO A  83
None
BGC  A 290 ( 3.7A)
None
BGC  A 290 (-3.4A)
BGC  A 290 (-4.9A)
1.09A 3jb3A-1woqA:
undetectable
3jb3A-1woqA:
13.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDT_A_VORA506_1
(CHOLESTEROL
24-HYDROXYLASE)
1woq INORGANIC
POLYPHOSPHATE/ATP-GL
UCOMANNOKINASE

(Arthrobacter
sp.
KM)
5 / 9 LEU A 110
VAL A  62
ILE A  24
ALA A 255
THR A  81
None
1.29A 3mdtA-1woqA:
undetectable
3mdtA-1woqA:
23.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3V_A_TOPA187_1
(DIHYDROFOLATE
REDUCTASE)
1woq INORGANIC
POLYPHOSPHATE/ATP-GL
UCOMANNOKINASE

(Arthrobacter
sp.
KM)
5 / 12 ILE A 241
GLU A 210
PHE A 206
ILE A 153
VAL A 220
None
1.10A 3s3vA-1woqA:
undetectable
3s3vA-1woqA:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BB2_B_STRB1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)
1woq INORGANIC
POLYPHOSPHATE/ATP-GL
UCOMANNOKINASE

(Arthrobacter
sp.
KM)
5 / 11 ALA A 183
SER A 184
PHE A 218
ILE A 147
HIS A 208
None
1.12A 4bb2A-1woqA:
0.0
4bb2B-1woqA:
0.0
4bb2A-1woqA:
22.16
4bb2B-1woqA:
11.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_A_HCYA1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)
1woq INORGANIC
POLYPHOSPHATE/ATP-GL
UCOMANNOKINASE

(Arthrobacter
sp.
KM)
5 / 12 ALA A 183
SER A 184
PHE A 218
ILE A 147
PHE A 206
None
1.07A 4c49A-1woqA:
undetectable
4c49A-1woqA:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_C_HCYC1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)
1woq INORGANIC
POLYPHOSPHATE/ATP-GL
UCOMANNOKINASE

(Arthrobacter
sp.
KM)
5 / 12 SER A 184
PHE A 218
ILE A 147
PHE A 206
HIS A 208
None
1.17A 4c49C-1woqA:
undetectable
4c49C-1woqA:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_D_HCYD1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)
1woq INORGANIC
POLYPHOSPHATE/ATP-GL
UCOMANNOKINASE

(Arthrobacter
sp.
KM)
5 / 12 SER A 184
PHE A 218
ILE A 147
PHE A 206
HIS A 208
None
1.22A 4c49D-1woqA:
undetectable
4c49D-1woqA:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L1A_A_AB1A101_1
(MDR769 HIV-1
PROTEASE)
1woq INORGANIC
POLYPHOSPHATE/ATP-GL
UCOMANNOKINASE

(Arthrobacter
sp.
KM)
5 / 11 ARG A  40
GLY A 254
ALA A 126
ASP A 125
ILE A 219
None
1.10A 4l1aA-1woqA:
undetectable
4l1aA-1woqA:
18.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UUU_B_SAMB1548_0
(CYSTATHIONINE
BETA-SYNTHASE)
1woq INORGANIC
POLYPHOSPHATE/ATP-GL
UCOMANNOKINASE

(Arthrobacter
sp.
KM)
5 / 11 LEU A 163
ASP A 123
VAL A 146
THR A 148
ILE A 153
None
BGC  A 290 (-2.9A)
None
None
None
1.33A 4uuuB-1woqA:
undetectable
4uuuB-1woqA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X5J_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)
1woq INORGANIC
POLYPHOSPHATE/ATP-GL
UCOMANNOKINASE

(Arthrobacter
sp.
KM)
5 / 12 ILE A  15
ALA A 256
LEU A  36
ARG A  42
ILE A  17
None
None
None
PO4  A 281 (-3.7A)
None
1.09A 4x5jA-1woqA:
undetectable
4x5jA-1woqA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XE5_A_OBNA1104_1
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)
1woq INORGANIC
POLYPHOSPHATE/ATP-GL
UCOMANNOKINASE

(Arthrobacter
sp.
KM)
5 / 12 GLU A  70
LEU A  31
GLU A  64
GLY A  16
ALA A 255
None
1.12A 4xe5A-1woqA:
undetectable
4xe5A-1woqA:
15.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y0Q_A_PX9A201_0
(BETA-LACTOGLOBULIN)
1woq INORGANIC
POLYPHOSPHATE/ATP-GL
UCOMANNOKINASE

(Arthrobacter
sp.
KM)
5 / 12 LEU A 212
LEU A 149
ILE A 147
LEU A 145
LEU A 235
None
1.03A 4y0qA-1woqA:
undetectable
4y0qA-1woqA:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YP2_B_NCAB302_0
(RIBOSOME-INACTIVATIN
G PROTEIN MOMORDIN I)
1woq INORGANIC
POLYPHOSPHATE/ATP-GL
UCOMANNOKINASE

(Arthrobacter
sp.
KM)
5 / 9 ILE A  15
GLY A  26
ILE A  28
ALA A  71
GLU A  70
None
1.13A 4yp2B-1woqA:
undetectable
4yp2B-1woqA:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BPH_A_ACTA403_0
(D-ALANINE--D-ALANINE
LIGASE)
1woq INORGANIC
POLYPHOSPHATE/ATP-GL
UCOMANNOKINASE

(Arthrobacter
sp.
KM)
4 / 6 TYR A 198
GLY A 223
SER A 225
LEU A 149
None
1.25A 5bphA-1woqA:
undetectable
5bphA-1woqA:
22.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BPH_C_ACTC403_0
(D-ALANINE--D-ALANINE
LIGASE)
1woq INORGANIC
POLYPHOSPHATE/ATP-GL
UCOMANNOKINASE

(Arthrobacter
sp.
KM)
4 / 4 TYR A 198
GLY A 223
SER A 225
LEU A 149
None
1.23A 5bphC-1woqA:
undetectable
5bphC-1woqA:
22.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BPH_D_ACTD403_0
(D-ALANINE--D-ALANINE
LIGASE)
1woq INORGANIC
POLYPHOSPHATE/ATP-GL
UCOMANNOKINASE

(Arthrobacter
sp.
KM)
4 / 6 TYR A 198
GLY A 223
SER A 225
LEU A 149
None
1.22A 5bphD-1woqA:
undetectable
5bphD-1woqA:
22.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CF9_B_NCAB302_0
(RIBOSOME-INACTIVATIN
G PROTEIN MOMORDIN I)
1woq INORGANIC
POLYPHOSPHATE/ATP-GL
UCOMANNOKINASE

(Arthrobacter
sp.
KM)
5 / 9 ILE A  15
GLY A  26
ILE A  28
ALA A  71
GLU A  70
None
1.14A 5cf9B-1woqA:
undetectable
5cf9B-1woqA:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_A_PCFA1805_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)
1woq INORGANIC
POLYPHOSPHATE/ATP-GL
UCOMANNOKINASE

(Arthrobacter
sp.
KM)
4 / 7 PHE A 213
HIS A 208
ILE A 174
SER A 155
None
1.06A 5vkqA-1woqA:
0.0
5vkqD-1woqA:
0.0
5vkqA-1woqA:
10.16
5vkqD-1woqA:
10.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_B_PCFB1802_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)
1woq INORGANIC
POLYPHOSPHATE/ATP-GL
UCOMANNOKINASE

(Arthrobacter
sp.
KM)
4 / 7 SER A 155
PHE A 213
HIS A 208
ILE A 174
None
1.06A 5vkqA-1woqA:
undetectable
5vkqB-1woqA:
undetectable
5vkqA-1woqA:
10.16
5vkqB-1woqA:
10.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_C_PCFC1803_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)
1woq INORGANIC
POLYPHOSPHATE/ATP-GL
UCOMANNOKINASE

(Arthrobacter
sp.
KM)
4 / 8 SER A 155
PHE A 213
HIS A 208
ILE A 174
None
1.04A 5vkqB-1woqA:
undetectable
5vkqC-1woqA:
undetectable
5vkqB-1woqA:
10.16
5vkqC-1woqA:
10.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_D_PCFD1803_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)
1woq INORGANIC
POLYPHOSPHATE/ATP-GL
UCOMANNOKINASE

(Arthrobacter
sp.
KM)
4 / 7 SER A 155
PHE A 213
HIS A 208
ILE A 174
None
1.04A 5vkqC-1woqA:
undetectable
5vkqD-1woqA:
undetectable
5vkqC-1woqA:
10.16
5vkqD-1woqA:
10.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DH6_A_017A104_1
(PROTEASE)
1woq INORGANIC
POLYPHOSPHATE/ATP-GL
UCOMANNOKINASE

(Arthrobacter
sp.
KM)
5 / 12 ALA A 132
VAL A 144
ILE A 219
LEU A 217
ILE A 158
None
1.06A 6dh6B-1woqA:
undetectable
6dh6B-1woqA:
17.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HWD_K_BO2K301_0
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)
1woq INORGANIC
POLYPHOSPHATE/ATP-GL
UCOMANNOKINASE

(Arthrobacter
sp.
KM)
5 / 11 ALA A 255
ALA A 250
ALA A 126
GLY A  27
GLY A  26
None
0.88A 6hwdK-1woqA:
undetectable
6hwdL-1woqA:
undetectable
6hwdK-1woqA:
15.19
6hwdL-1woqA:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HWD_Y_BO2Y301_0
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)
1woq INORGANIC
POLYPHOSPHATE/ATP-GL
UCOMANNOKINASE

(Arthrobacter
sp.
KM)
5 / 11 ALA A 255
ALA A 250
ALA A 126
GLY A  27
GLY A  26
None
0.88A 6hwdY-1woqA:
undetectable
6hwdZ-1woqA:
undetectable
6hwdY-1woqA:
15.19
6hwdZ-1woqA:
17.95