SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1woy'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LII_A_ADNA699_2
(ADENOSINE KINASE)		 1woy METHIONYL-TRNA
SYNTHETASE
(Thermus
thermophilus) 		4 / 4 SER A 337
LEU A  20
TYR A 323
GLY A 292
 None
 1.41A 1liiA-1woyA:
1.9		 1liiA-1woyA:
24.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QU2_A_MRCA1993_1
(ISOLEUCYL-TRNA
SYNTHETASE)		 1woy METHIONYL-TRNA
SYNTHETASE
(Thermus
thermophilus) 		5 / 12 HIS A  19
GLY A  21
HIS A  22
GLY A 258
ASP A 260
 None
 0.61A 1qu2A-1woyA:
24.3		 1qu2A-1woyA:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V8B_B_ADNB1502_2
(ADENOSYLHOMOCYSTEINA
SE)		 1woy METHIONYL-TRNA
SYNTHETASE
(Thermus
thermophilus) 		3 / 3 GLU A 339
GLU A 327
LEU A  20
 None
 0.78A 1v8bB-1woyA:
2.1		 1v8bB-1woyA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Y0X_X_T44X500_1
(THYROID HORMONE
RECEPTOR BETA-1)		 1woy METHIONYL-TRNA
SYNTHETASE
(Thermus
thermophilus) 		5 / 12 ILE A 418
MET A 363
ARG A 435
LEU A 467
ILE A 489
 None
 1.34A 1y0xX-1woyA:
undetectable		 1y0xX-1woyA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVD_B_SAMB601_0
(CATECHOL-O-METHYLTRA
NSFERASE)		 1woy METHIONYL-TRNA
SYNTHETASE
(Thermus
thermophilus) 		5 / 12 GLY A 354
VAL A 495
ASP A 351
ALA A 350
TYR A 345
 None
 1.16A 2avdB-1woyA:
undetectable		 2avdB-1woyA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVV_A_MK1A901_2
(POL POLYPROTEIN)		 1woy METHIONYL-TRNA
SYNTHETASE
(Thermus
thermophilus) 		3 / 3 ASP A 333
VAL A 336
PRO A 308
 None
 0.80A 2avvA-1woyA:
undetectable		 2avvA-1woyA:
9.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DCF_A_ACAA502_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 1woy METHIONYL-TRNA
SYNTHETASE
(Thermus
thermophilus) 		5 / 12 ALA A 276
TYR A 240
VAL A 103
GLY A 277
ILE A 278
 None
 1.21A 2dcfA-1woyA:
undetectable		 2dcfA-1woyA:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJ3_C_GBNC1414_1
(BRANCHED-CHAIN AMINO
ACID
AMINOTRANSFERASE)		 1woy METHIONYL-TRNA
SYNTHETASE
(Thermus
thermophilus) 		5 / 8 TYR A  57
GLU A  65
GLY A  64
ALA A  60
ALA A  63
 None
 1.29A 2ej3C-1woyA:
undetectable		 2ej3C-1woyA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HTU_A_BCZA801_0
(NEURAMINIDASE)		 1woy METHIONYL-TRNA
SYNTHETASE
(Thermus
thermophilus) 		5 / 12 LEU A 452
SER A 449
ARG A 446
GLU A 443
TYR A 410
 None
 1.43A 2htuA-1woyA:
undetectable		 2htuA-1woyA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VE3_B_REAB1445_1
(PUTATIVE CYTOCHROME
P450 120)		 1woy METHIONYL-TRNA
SYNTHETASE
(Thermus
thermophilus) 		5 / 12 PHE A  92
THR A  96
ALA A  60
VAL A  74
GLY A  76
 None
 1.29A 2ve3B-1woyA:
undetectable		 2ve3B-1woyA:
23.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1359_1
(PROSTAGLANDIN
REDUCTASE 2)		 1woy METHIONYL-TRNA
SYNTHETASE
(Thermus
thermophilus) 		4 / 6 THR A  96
GLU A  97
PHE A  92
ILE A  11
 None
 1.34A 2w98B-1woyA:
2.2		 2w98B-1woyA:
20.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2X1L_A_ADNA601_1
(METHIONYL-TRNA
SYNTHETASE)		 1woy METHIONYL-TRNA
SYNTHETASE
(Thermus
thermophilus) 		6 / 11 HIS A  19
GLY A  21
HIS A  22
GLY A 258
ASP A 260
ILE A 261
 None
 0.69A 2x1lA-1woyA:
43.6		 2x1lA-1woyA:
39.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2X1L_B_ADNB601_1
(METHIONYL-TRNA
SYNTHETASE)		 1woy METHIONYL-TRNA
SYNTHETASE
(Thermus
thermophilus) 		6 / 12 HIS A  19
GLY A  21
HIS A  22
GLY A 258
ASP A 260
ILE A 261
 None
 0.68A 2x1lB-1woyA:
46.6		 2x1lB-1woyA:
39.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2X1L_B_ADNB601_1
(METHIONYL-TRNA
SYNTHETASE)		 1woy METHIONYL-TRNA
SYNTHETASE
(Thermus
thermophilus) 		5 / 12 HIS A  19
GLY A  21
HIS A  22
ILE A 261
LEU A 290
 None
 0.73A 2x1lB-1woyA:
46.6		 2x1lB-1woyA:
39.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2X1L_C_ADNC601_1
(METHIONYL-TRNA
SYNTHETASE)		 1woy METHIONYL-TRNA
SYNTHETASE
(Thermus
thermophilus) 		6 / 11 HIS A  19
GLY A  21
HIS A  22
GLY A 258
ASP A 260
ILE A 261
 None
 0.63A 2x1lC-1woyA:
46.2		 2x1lC-1woyA:
39.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZIA_B_CL9B401_2
(DEOXYCYTIDINE KINASE)		 1woy METHIONYL-TRNA
SYNTHETASE
(Thermus
thermophilus) 		4 / 4 ARG A 321
ASP A 318
LEU A 404
ARG A  37
 None
 1.32A 2ziaB-1woyA:
0.8		 2ziaB-1woyA:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A65_A_ACAA601_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 1woy METHIONYL-TRNA
SYNTHETASE
(Thermus
thermophilus) 		5 / 12 ALA A 276
TYR A 240
VAL A 103
GLY A 277
ILE A 278
 None
 1.23A 3a65A-1woyA:
undetectable		 3a65A-1woyA:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_A_CHDA152_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 1woy METHIONYL-TRNA
SYNTHETASE
(Thermus
thermophilus) 		3 / 3 VAL A 210
LYS A 207
HIS A 100
 None
 0.93A 3elzA-1woyA:
undetectable		 3elzA-1woyA:
13.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S56_B_ROCB203_1
(PROTEASE)		 1woy METHIONYL-TRNA
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 LEU A 469
LEU A 467
PRO A 373
ILE A 372
 None
 0.96A 3s56B-1woyA:
undetectable		 3s56B-1woyA:
10.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1woy METHIONYL-TRNA
SYNTHETASE
(Thermus
thermophilus) 		4 / 6 ILE A 174
LEU A 170
ARG A 282
MET A 280
 None
 1.06A 3wg7A-1woyA:
1.7
3wg7J-1woyA:
undetectable		 3wg7A-1woyA:
21.79
3wg7J-1woyA:
8.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A9J_C_TYLC1184_1
(BROMODOMAIN
CONTAINING 2)		 1woy METHIONYL-TRNA
SYNTHETASE
(Thermus
thermophilus) 		4 / 5 VAL A 267
LEU A 170
LEU A 194
ILE A 181
 None
 0.95A 4a9jC-1woyA:
0.2		 4a9jC-1woyA:
14.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AX8_A_SAMA1474_1
(WBDD)		 1woy METHIONYL-TRNA
SYNTHETASE
(Thermus
thermophilus) 		4 / 6 TYR A  24
ASP A 260
GLU A 189
LEU A 256
 None
 1.37A 4ax8A-1woyA:
undetectable		 4ax8A-1woyA:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AZW_A_SAMA1451_0
(WBDD)		 1woy METHIONYL-TRNA
SYNTHETASE
(Thermus
thermophilus) 		5 / 12 TYR A  24
GLY A 258
GLU A 189
LEU A 256
VAL A 286
 None
 1.26A 4azwA-1woyA:
undetectable		 4azwA-1woyA:
23.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F3T_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 1woy METHIONYL-TRNA
SYNTHETASE
(Thermus
thermophilus) 		4 / 6 LEU A 320
LYS A 314
LEU A 341
GLU A 338
 None
 1.16A 4f3tA-1woyA:
2.2		 4f3tA-1woyA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K36_A_SAMA504_0
(ANAEROBIC
SULFATASE-MATURATING
ENZYME)		 1woy METHIONYL-TRNA
SYNTHETASE
(Thermus
thermophilus) 		5 / 12 ARG A 474
LEU A 475
VAL A 473
ILE A 450
LEU A 469
 None
 1.38A 4k36A-1woyA:
0.8		 4k36A-1woyA:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K36_B_SAMB504_0
(ANAEROBIC
SULFATASE-MATURATING
ENZYME)		 1woy METHIONYL-TRNA
SYNTHETASE
(Thermus
thermophilus) 		5 / 12 ARG A 474
LEU A 475
VAL A 473
ILE A 450
LEU A 469
 None
 1.38A 4k36B-1woyA:
0.8		 4k36B-1woyA:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K37_A_SAMA504_0
(ANAEROBIC
SULFATASE-MATURATING
ENZYME)		 1woy METHIONYL-TRNA
SYNTHETASE
(Thermus
thermophilus) 		5 / 11 ARG A 474
LEU A 475
VAL A 473
ILE A 450
LEU A 469
 None
 1.42A 4k37A-1woyA:
undetectable		 4k37A-1woyA:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K37_B_SAMB504_0
(ANAEROBIC
SULFATASE-MATURATING
ENZYME)		 1woy METHIONYL-TRNA
SYNTHETASE
(Thermus
thermophilus) 		5 / 11 ARG A 474
LEU A 475
VAL A 473
ILE A 450
LEU A 469
 None
 1.42A 4k37B-1woyA:
0.8		 4k37B-1woyA:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MX0_A_BCZA513_0
(NEURAMINIDASE)		 1woy METHIONYL-TRNA
SYNTHETASE
(Thermus
thermophilus) 		5 / 12 LEU A 452
SER A 449
ARG A 446
GLU A 443
TYR A 410
 None
 1.50A 4mx0A-1woyA:
undetectable		 4mx0A-1woyA:
18.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UBS_A_DIFA502_1
(PENTALENIC ACID
SYNTHASE)		 1woy METHIONYL-TRNA
SYNTHETASE
(Thermus
thermophilus) 		5 / 9 ARG A 392
LEU A 391
THR A 385
LEU A 387
ILE A 447
 None
 1.36A 4ubsA-1woyA:
1.4		 4ubsA-1woyA:
23.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XI3_C_29SC601_1
(ESTROGEN RECEPTOR)		 1woy METHIONYL-TRNA
SYNTHETASE
(Thermus
thermophilus) 		5 / 12 THR A 271
LEU A 273
LEU A 231
LEU A 232
LEU A 201
 None
 0.91A 4xi3C-1woyA:
undetectable		 4xi3C-1woyA:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HG0_B_SAMB301_0
(PANTOTHENATE
SYNTHETASE)		 1woy METHIONYL-TRNA
SYNTHETASE
(Thermus
thermophilus) 		5 / 12 HIS A  19
GLY A  21
HIS A  22
VAL A 226
GLY A 258
 None
 0.86A 5hg0B-1woyA:
6.3		 5hg0B-1woyA:
17.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HWA_A_GCSA302_1
(CHITOSANASE)		 1woy METHIONYL-TRNA
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 THR A  95
ASP A  50
ASP A 229
GLY A  53
 None
 0.90A 5hwaA-1woyA:
undetectable		 5hwaA-1woyA:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NNA_B_BZMB301_0
(ISATIN HYDROLASE A)		 1woy METHIONYL-TRNA
SYNTHETASE
(Thermus
thermophilus) 		5 / 12 ILE A 450
LEU A 451
PRO A 454
VAL A 473
ASP A  39
 None
 1.09A 5nnaB-1woyA:
undetectable		 5nnaB-1woyA:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NNA_C_BZMC301_0
(ISATIN HYDROLASE A)		 1woy METHIONYL-TRNA
SYNTHETASE
(Thermus
thermophilus) 		5 / 12 ILE A 450
LEU A 451
PRO A 454
VAL A 473
ASP A  39
 None
 1.11A 5nnaC-1woyA:
undetectable		 5nnaC-1woyA:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O96_C_SAMC501_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)		 1woy METHIONYL-TRNA
SYNTHETASE
(Thermus
thermophilus) 		4 / 7 GLY A  48
LEU A 256
THR A  26
ALA A  29
 None
 0.65A 5o96C-1woyA:
undetectable		 5o96C-1woyA:
18.29