SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1wps'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EJ0_A_SAMA301_0
(FTSJ)		 1wps HUT OPERON POSITIVE
REGULATORY PROTEIN
(Bacillus
subtilis) 		5 / 12 ALA A  82
GLY A  10
GLY A 142
LEU A  16
ARG A   7
 None
 0.97A 1ej0A-1wpsA:
undetectable		 1ej0A-1wpsA:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_D_VDYD1001_5
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 1wps HUT OPERON POSITIVE
REGULATORY PROTEIN
(Bacillus
subtilis) 		3 / 3 THR A  79
LEU A  83
VAL A  86
 None
 0.46A 1mz9E-1wpsA:
undetectable		 1mz9E-1wpsA:
26.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DDW_B_PXLB1005_1
(PYRIDOXINE KINASE)		 1wps HUT OPERON POSITIVE
REGULATORY PROTEIN
(Bacillus
subtilis) 		4 / 7 SER A  95
LEU A  93
THR A  87
HIS A  84
 None
 0.97A 2ddwB-1wpsA:
undetectable		 2ddwB-1wpsA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QBL_A_CAMA517_0
(CYTOCHROME P450-CAM)		 1wps HUT OPERON POSITIVE
REGULATORY PROTEIN
(Bacillus
subtilis) 		4 / 7 LEU A  83
VAL A  86
THR A  87
VAL A 100
 None
 0.72A 2qblA-1wpsA:
undetectable		 2qblA-1wpsA:
17.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3THR_A_C2FA1100_1
(GLYCINE
N-METHYLTRANSFERASE)		 1wps HUT OPERON POSITIVE
REGULATORY PROTEIN
(Bacillus
subtilis) 		3 / 3 LEU A  83
HIS A  84
MET A  80
 None
 0.76A 3thrD-1wpsA:
undetectable		 3thrD-1wpsA:
19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_C_ZPCC1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 1wps HUT OPERON POSITIVE
REGULATORY PROTEIN
(Bacillus
subtilis) 		5 / 12 VAL A  50
ILE A  54
ILE A 129
HIS A  84
VAL A 123
 None
 1.32A 4a97B-1wpsA:
0.0
4a97C-1wpsA:
undetectable		 4a97B-1wpsA:
19.18
4a97C-1wpsA:
19.18