SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1wrj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4K_A_DR7A301_1
(PROTEASE)		 1wrj METHYLATED-DNA--PROT
EIN-CYSTEINE
METHYLTRANSFERASE
(Sulfurisphaera
tokodaii) 		5 / 12 ARG A 140
LEU A 129
ILE A  83
GLY A  86
ILE A 124
 None
 1.10A 2o4kA-1wrjA:
0.0		 2o4kA-1wrjA:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OD9_A_NCAA3721_0
(NAD-DEPENDENT
DEACETYLASE HST2)		 1wrj METHYLATED-DNA--PROT
EIN-CYSTEINE
METHYLTRANSFERASE
(Sulfurisphaera
tokodaii) 		3 / 3 PHE A  53
PHE A  11
PHE A  28
 None
 0.83A 2od9A-1wrjA:
undetectable		 2od9A-1wrjA:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQG_A_NCAA3721_0
(NAD-DEPENDENT
DEACETYLASE HST2)		 1wrj METHYLATED-DNA--PROT
EIN-CYSTEINE
METHYLTRANSFERASE
(Sulfurisphaera
tokodaii) 		3 / 3 PHE A  53
PHE A  11
PHE A  28
 None
 0.83A 2qqgA-1wrjA:
undetectable		 2qqgA-1wrjA:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_C_CHDC1265_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1wrj METHYLATED-DNA--PROT
EIN-CYSTEINE
METHYLTRANSFERASE
(Sulfurisphaera
tokodaii) 		4 / 5 PHE A  11
PHE A  53
LEU A  49
PHE A  45
 None
 1.24A 2y69C-1wrjA:
undetectable
2y69J-1wrjA:
undetectable		 2y69C-1wrjA:
16.60
2y69J-1wrjA:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_P_CHDP1265_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1wrj METHYLATED-DNA--PROT
EIN-CYSTEINE
METHYLTRANSFERASE
(Sulfurisphaera
tokodaii) 		4 / 5 PHE A  11
PHE A  53
LEU A  49
PHE A  45
 None
 1.31A 2y69P-1wrjA:
undetectable
2y69W-1wrjA:
undetectable		 2y69P-1wrjA:
16.60
2y69W-1wrjA:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1wrj METHYLATED-DNA--PROT
EIN-CYSTEINE
METHYLTRANSFERASE
(Sulfurisphaera
tokodaii) 		4 / 5 PHE A  11
PHE A  53
LEU A  49
PHE A  45
 None
 1.23A 3abmC-1wrjA:
undetectable
3abmJ-1wrjA:
undetectable		 3abmC-1wrjA:
16.60
3abmJ-1wrjA:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1wrj METHYLATED-DNA--PROT
EIN-CYSTEINE
METHYLTRANSFERASE
(Sulfurisphaera
tokodaii) 		4 / 5 PHE A  11
PHE A  53
LEU A  49
PHE A  45
 None
 1.26A 3abmP-1wrjA:
undetectable
3abmW-1wrjA:
undetectable		 3abmP-1wrjA:
16.60
3abmW-1wrjA:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1wrj METHYLATED-DNA--PROT
EIN-CYSTEINE
METHYLTRANSFERASE
(Sulfurisphaera
tokodaii) 		4 / 5 PHE A  11
PHE A  53
LEU A  49
PHE A  45
 None
 1.23A 3ag3C-1wrjA:
undetectable
3ag3J-1wrjA:
undetectable		 3ag3C-1wrjA:
16.60
3ag3J-1wrjA:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1wrj METHYLATED-DNA--PROT
EIN-CYSTEINE
METHYLTRANSFERASE
(Sulfurisphaera
tokodaii) 		4 / 7 LEU A  60
PHE A  45
LEU A  49
PHE A  53
 None
 0.94A 3ag4P-1wrjA:
undetectable
3ag4W-1wrjA:
undetectable		 3ag4P-1wrjA:
16.60
3ag4W-1wrjA:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_P_CHDP1271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 1wrj METHYLATED-DNA--PROT
EIN-CYSTEINE
METHYLTRANSFERASE
(Sulfurisphaera
tokodaii) 		4 / 7 LEU A  60
PHE A  45
LEU A  49
PHE A  53
 None
 1.01A 3asnP-1wrjA:
undetectable
3asnW-1wrjA:
undetectable		 3asnP-1wrjA:
16.60
3asnW-1wrjA:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_C_CHDC271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 1wrj METHYLATED-DNA--PROT
EIN-CYSTEINE
METHYLTRANSFERASE
(Sulfurisphaera
tokodaii) 		4 / 8 LEU A  60
PHE A  45
LEU A  49
PHE A  53
 None
 0.98A 3asoC-1wrjA:
undetectable
3asoJ-1wrjA:
undetectable		 3asoC-1wrjA:
16.60
3asoJ-1wrjA:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXX_C_DR7C100_1
(HIV-1 PROTEASE)		 1wrj METHYLATED-DNA--PROT
EIN-CYSTEINE
METHYLTRANSFERASE
(Sulfurisphaera
tokodaii) 		5 / 12 ARG A 140
LEU A 129
ILE A  83
GLY A  86
ILE A 124
 None
 0.98A 3oxxC-1wrjA:
undetectable		 3oxxC-1wrjA:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUD_A_SUEA1201_2
(NS3 PROTEASE, NS4A
PROTEIN)		 1wrj METHYLATED-DNA--PROT
EIN-CYSTEINE
METHYLTRANSFERASE
(Sulfurisphaera
tokodaii) 		4 / 4 PHE A  46
TYR A  41
ILE A 118
LEU A 115
 None
 1.43A 3sudA-1wrjA:
undetectable		 3sudA-1wrjA:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1wrj METHYLATED-DNA--PROT
EIN-CYSTEINE
METHYLTRANSFERASE
(Sulfurisphaera
tokodaii) 		4 / 6 LEU A  60
PHE A  45
LEU A  49
PHE A  53
 None
 0.93A 3wg7C-1wrjA:
undetectable
3wg7J-1wrjA:
undetectable		 3wg7C-1wrjA:
16.60
3wg7J-1wrjA:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1wrj METHYLATED-DNA--PROT
EIN-CYSTEINE
METHYLTRANSFERASE
(Sulfurisphaera
tokodaii) 		4 / 7 LEU A  60
PHE A  45
LEU A  49
PHE A  53
 None
 0.97A 5b1aC-1wrjA:
undetectable
5b1aJ-1wrjA:
undetectable		 5b1aC-1wrjA:
16.60
5b1aJ-1wrjA:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1wrj METHYLATED-DNA--PROT
EIN-CYSTEINE
METHYLTRANSFERASE
(Sulfurisphaera
tokodaii) 		4 / 7 LEU A  60
PHE A  45
LEU A  49
PHE A  53
 None
 0.97A 5b1aP-1wrjA:
undetectable
5b1aW-1wrjA:
undetectable		 5b1aP-1wrjA:
16.60
5b1aW-1wrjA:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1wrj METHYLATED-DNA--PROT
EIN-CYSTEINE
METHYLTRANSFERASE
(Sulfurisphaera
tokodaii) 		4 / 7 LEU A  60
PHE A  45
LEU A  49
PHE A  53
 None
 0.87A 5b1bP-1wrjA:
undetectable
5b1bW-1wrjA:
undetectable		 5b1bP-1wrjA:
16.60
5b1bW-1wrjA:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NUJ_A_Z80A201_1
(BETA-LACTOGLOBULIN)		 1wrj METHYLATED-DNA--PROT
EIN-CYSTEINE
METHYLTRANSFERASE
(Sulfurisphaera
tokodaii) 		4 / 8 ALA A  95
VAL A 105
LEU A 109
ILE A  83
 None
 0.82A 5nujA-1wrjA:
undetectable		 5nujA-1wrjA:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1wrj METHYLATED-DNA--PROT
EIN-CYSTEINE
METHYLTRANSFERASE
(Sulfurisphaera
tokodaii) 		4 / 5 PHE A  11
PHE A  53
LEU A  49
PHE A  45
 None
 1.21A 5wauC-1wrjA:
undetectable
5wauJ-1wrjA:
undetectable		 5wauC-1wrjA:
16.60
5wauJ-1wrjA:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_C_CHDC308_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1wrj METHYLATED-DNA--PROT
EIN-CYSTEINE
METHYLTRANSFERASE
(Sulfurisphaera
tokodaii) 		4 / 5 PHE A  11
PHE A  53
LEU A  49
PHE A  45
 None
 1.20A 5wauc-1wrjA:
undetectable
5wauj-1wrjA:
undetectable		 5wauc-1wrjA:
16.60
5wauj-1wrjA:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_P_CHDP304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1wrj METHYLATED-DNA--PROT
EIN-CYSTEINE
METHYLTRANSFERASE
(Sulfurisphaera
tokodaii) 		4 / 7 LEU A  60
PHE A  45
LEU A  49
PHE A  53
 None
 0.95A 5x1fP-1wrjA:
undetectable
5x1fW-1wrjA:
undetectable		 5x1fP-1wrjA:
16.60
5x1fW-1wrjA:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_C_CHDC308_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1wrj METHYLATED-DNA--PROT
EIN-CYSTEINE
METHYLTRANSFERASE
(Sulfurisphaera
tokodaii) 		4 / 5 PHE A  11
PHE A  53
LEU A  49
PHE A  45
 None
 1.27A 5xdqC-1wrjA:
undetectable
5xdqJ-1wrjA:
undetectable		 5xdqC-1wrjA:
16.60
5xdqJ-1wrjA:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1wrj METHYLATED-DNA--PROT
EIN-CYSTEINE
METHYLTRANSFERASE
(Sulfurisphaera
tokodaii) 		4 / 5 PHE A  11
PHE A  53
LEU A  49
PHE A  45
 None
 1.25A 5xdqP-1wrjA:
undetectable
5xdqW-1wrjA:
undetectable		 5xdqP-1wrjA:
16.60
5xdqW-1wrjA:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_C_CHDC307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1wrj METHYLATED-DNA--PROT
EIN-CYSTEINE
METHYLTRANSFERASE
(Sulfurisphaera
tokodaii) 		4 / 7 LEU A  60
PHE A  45
LEU A  49
PHE A  53
 None
 0.90A 5z84C-1wrjA:
undetectable
5z84J-1wrjA:
undetectable		 5z84C-1wrjA:
16.60
5z84J-1wrjA:
18.49