SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1wru'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FBM_B_RTLB951_0
(PROTEIN (CARTILAGE
OLIGOMERIC MATRIX
PROTEIN))		 1wru 43 KDA TAIL PROTEIN
(Escherichia
virus
Mu) 		4 / 4 THR A 299
LEU A 312
LEU A 271
GLN A 267
 None
 1.18A 1fbmA-1wruA:
undetectable		 1fbmA-1wruA:
8.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IBG_H_OBNH1_1
(IGG2B-KAPPA 40-50
FAB (HEAVY CHAIN))		 1wru 43 KDA TAIL PROTEIN
(Escherichia
virus
Mu) 		4 / 6 LEU A 110
PHE A 174
TYR A 150
VAL A 125
 None
 1.31A 1ibgH-1wruA:
undetectable		 1ibgH-1wruA:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FUM_D_MIXD3539_2
(PROBABLE
SERINE/THREONINE-PRO
TEIN KINASE PKNB)		 1wru 43 KDA TAIL PROTEIN
(Escherichia
virus
Mu) 		3 / 3 VAL A  29
VAL A 173
ASP A 116
 None
 0.78A 2fumD-1wruA:
2.2		 2fumD-1wruA:
23.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LNW_A_T3A501_2
(THYROID HORMONE
RECEPTOR ALPHA)		 1wru 43 KDA TAIL PROTEIN
(Escherichia
virus
Mu) 		3 / 3 ILE A  58
MET A 293
ARG A 286
 None
 0.92A 4lnwA-1wruA:
undetectable		 4lnwA-1wruA:
19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LNX_A_T3A502_2
(THYROID HORMONE
RECEPTOR ALPHA)		 1wru 43 KDA TAIL PROTEIN
(Escherichia
virus
Mu) 		3 / 3 ILE A  58
MET A 293
ARG A 286
 None
 0.93A 4lnxA-1wruA:
undetectable		 4lnxA-1wruA:
19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZT_A_RTLA201_1
(RETINOL-BINDING
PROTEIN 2)		 1wru 43 KDA TAIL PROTEIN
(Escherichia
virus
Mu) 		3 / 3 PHE A 200
THR A 309
LEU A 271
 None
 0.79A 4qztA-1wruA:
undetectable		 4qztA-1wruA:
15.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X5I_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 1wru 43 KDA TAIL PROTEIN
(Escherichia
virus
Mu) 		3 / 3 ASP A 131
ARG A 268
ARG A 336
 None
 0.95A 4x5iA-1wruA:
undetectable		 4x5iA-1wruA:
18.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EAJ_B_FOLB201_1
(DIHYDROFOLATE
REDUCTASE)		 1wru 43 KDA TAIL PROTEIN
(Escherichia
virus
Mu) 		3 / 3 ASP A 131
ARG A 268
ARG A 336
 None
 0.85A 5eajB-1wruA:
undetectable		 5eajB-1wruA:
18.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JQB_B_IBPB706_1
(ENVELOPE
GLYCOPROTEIN
1,ENVELOPE
GLYCOPROTEIN
1,ENVELOPE
GLYCOPROTEIN 1
ENVELOPE
GLYCOPROTEIN 2)		 1wru 43 KDA TAIL PROTEIN
(Escherichia
virus
Mu) 		4 / 8 LEU A 143
LEU A  93
TYR A 121
LEU A 153
 None
 0.64A 5jqbA-1wruA:
undetectable
5jqbB-1wruA:
undetectable		 5jqbA-1wruA:
20.76
5jqbB-1wruA:
17.30