SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1wry'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5QGK_A_ACTA301_0 (PEROXISOMAL COENZYME A DIPHOSPHATASE NUDT7)	1wry	SH3 DOMAIN-BINDING GLUTAMIC ACID-RICH-LIKE PROTEIN (Homo sapiens)	3 / 3	VAL A 30 TYR A 86 GLN A 27	None	0.74A	5qgkA-1wryA: undetectable	5qgkA-1wryA: 19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5QGR_A_ACTA301_0 (PEROXISOMAL COENZYME A DIPHOSPHATASE NUDT7)	1wry	SH3 DOMAIN-BINDING GLUTAMIC ACID-RICH-LIKE PROTEIN (Homo sapiens)	3 / 3	VAL A 30 TYR A 86 GLN A 27	None	0.75A	5qgrA-1wryA: undetectable	5qgrA-1wryA: 19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5X80_B_SALB203_1 (UNCHARACTERIZED HTH-TYPE TRANSCRIPTIONAL REGULATOR RV2887)	1wry	SH3 DOMAIN-BINDING GLUTAMIC ACID-RICH-LIKE PROTEIN (Homo sapiens)	4 / 6	PRO A 74 TYR A 86 LEU A 102 VAL A 12	None	0.96A	5x80A-1wryA: undetectable 5x80B-1wryA: undetectable	5x80A-1wryA: 25.15 5x80B-1wryA: 25.15