SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ws0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S8F_B_BEZB1503_0
(RAS-RELATED PROTEIN
RAB-9A)		 1ws0 PEPTIDE DEFORMYLASE
1
(Bacillus
cereus) 		4 / 6 VAL A  63
GLU A 133
LEU A 126
PHE A 125
 None
NI  A 200 ( 4.1A)
None
None
 1.12A 1s8fB-1ws0A:
undetectable		 1s8fB-1ws0A:
26.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FB2_A_SAMA501_0
(MOLYBDENUM COFACTOR
BIOSYNTHESIS PROTEIN
A)		 1ws0 PEPTIDE DEFORMYLASE
1
(Bacillus
cereus) 		4 / 8 CYH A  90
GLU A  15
SER A 144
VAL A 100
 NI  A 200 (-2.2A)
None
None
None
 1.06A 2fb2A-1ws0A:
undetectable		 2fb2A-1ws0A:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD3_A_CHDA501_0
(FERROCHELATASE)		 1ws0 PEPTIDE DEFORMYLASE
1
(Bacillus
cereus) 		5 / 11 LEU A  28
LEU A  31
LEU A   4
ARG A 113
ILE A  73
 None
 1.18A 2qd3A-1ws0A:
undetectable		 2qd3A-1ws0A:
20.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YOE_C_FL7C1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 1ws0 PEPTIDE DEFORMYLASE
1
(Bacillus
cereus) 		4 / 8 GLY A  53
ILE A  73
VAL A  61
SER A  55
 None
 0.94A 2yoeB-1ws0A:
undetectable
2yoeC-1ws0A:
undetectable		 2yoeB-1ws0A:
19.67
2yoeC-1ws0A:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E5J_A_017A201_3
(PROTEASE)		 1ws0 PEPTIDE DEFORMYLASE
1
(Bacillus
cereus) 		3 / 3 ASP A  34
VAL A  52
LEU A  47
 None
 0.65A 5e5jB-1ws0A:
1.2		 5e5jB-1ws0A:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HP1_A_PPFA602_1
(HIV-1 REVERSE
TRANSCRIPTASE P66
SUBUNIT)		 1ws0 PEPTIDE DEFORMYLASE
1
(Bacillus
cereus) 		4 / 6 ASP A  66
GLY A  68
ASP A  62
ASP A  64
 None
 1.27A 5hp1A-1ws0A:
undetectable		 5hp1A-1ws0A:
16.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_A_ACTA310_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 1ws0 PEPTIDE DEFORMYLASE
1
(Bacillus
cereus) 		3 / 3 GLU A 133
HIS A 132
ARG A 128
 NI  A 200 ( 4.1A)
NI  A 200 (-3.2A)
None
 0.97A 5uunA-1ws0A:
undetectable		 5uunA-1ws0A:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_A_ACTA312_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 1ws0 PEPTIDE DEFORMYLASE
1
(Bacillus
cereus) 		3 / 3 ILE A 106
VAL A 108
PRO A  75
 None
 0.66A 5uunA-1ws0A:
undetectable		 5uunA-1ws0A:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_D_SUED1202_1
(NS3 PROTEASE)		 1ws0 PEPTIDE DEFORMYLASE
1
(Bacillus
cereus) 		4 / 9 PHE A 142
LEU A 137
VAL A  54
SER A  55
 None
 1.00A 6c2mD-1ws0A:
undetectable		 6c2mD-1ws0A:
21.43