SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1wsj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JB0_A_PQNA2001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 1wsj RIBONUCLEASE HI
(Escherichia
coli) 		5 / 9 SER A  12
GLY A  21
ALA A 139
LEU A 136
GLY A  23
 None
 1.40A 1jb0A-1wsjA:
undetectable		 1jb0A-1wsjA:
11.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RCT_A_RTLA140_1
(RETINOL-BINDING
PROTEIN II, CELLULAR)		 1wsj RIBONUCLEASE HI
(Escherichia
coli) 		3 / 3 GLN A  72
THR A   9
TRP A 118
 None
 0.95A 2rctA-1wsjA:
undetectable		 2rctA-1wsjA:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PCQ_A_PQNA847_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 1wsj RIBONUCLEASE HI
(Escherichia
coli) 		5 / 9 SER A  12
GLY A  21
ALA A 139
LEU A 136
GLY A  23
 None
 1.41A 3pcqA-1wsjA:
undetectable		 3pcqA-1wsjA:
11.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DM8_B_REAB1501_1
(RETINOIC ACID
RECEPTOR BETA)		 1wsj RIBONUCLEASE HI
(Escherichia
coli) 		5 / 12 ALA A  58
LEU A  26
ILE A  25
ARG A  31
GLY A  23
 None
 1.10A 4dm8B-1wsjA:
undetectable		 4dm8B-1wsjA:
18.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PUO_C_NVPC901_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)		 1wsj RIBONUCLEASE HI
(Escherichia
coli) 		4 / 8 LEU A  56
VAL A   5
TRP A 118
LEU A 111
 None
 0.93A 4puoC-1wsjA:
15.3		 4puoC-1wsjA:
15.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DNU_A_BEZA319_0
(SHKAI2IB)		 1wsj RIBONUCLEASE HI
(Escherichia
coli) 		4 / 5 GLN A   4
HIS A 114
ILE A  66
ILE A   7
 None
 0.92A 5dnuA-1wsjA:
undetectable		 5dnuA-1wsjA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DNV_A_BEZA304_0
(SHKAI2IB)		 1wsj RIBONUCLEASE HI
(Escherichia
coli) 		4 / 5 GLN A   4
HIS A 114
ILE A  66
ILE A   7
 None
 0.91A 5dnvA-1wsjA:
undetectable		 5dnvA-1wsjA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L8R_A_PQNA844_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 1wsj RIBONUCLEASE HI
(Escherichia
coli) 		5 / 9 SER A  12
GLY A  21
ALA A 139
LEU A 136
GLY A  23
 None
 1.41A 5l8rA-1wsjA:
undetectable		 5l8rA-1wsjA:
11.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0S_B_SAMB501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 1wsj RIBONUCLEASE HI
(Escherichia
coli) 		4 / 4 GLY A  23
ALA A  37
MET A  47
THR A 145
 None
 1.43A 5n0sB-1wsjA:
0.0		 5n0sB-1wsjA:
17.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_E_CVIE301_0
(REGULATORY PROTEIN
TETR)		 1wsj RIBONUCLEASE HI
(Escherichia
coli) 		5 / 12 ALA A  52
GLU A   6
LEU A  26
ILE A  25
ARG A 132
 None
 1.23A 5vlmE-1wsjA:
undetectable		 5vlmE-1wsjA:
21.78