SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1wsu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FE2_A_LAXA700_2
(PROSTAGLANDIN
ENDOPEROXIDE H
SYNTHASE-1)		 1wsu SELENOCYSTEINE-SPECI
FIC ELONGATION
FACTOR
(Moorella
thermoacetica) 		5 / 12 LEU A 610
PHE A 593
GLY A 594
ALA A 596
LEU A 602
 G  E  23 ( 4.6A)
None
None
G  E  23 ( 3.6A)
None
 1.11A 1fe2A-1wsuA:
undetectable		 1fe2A-1wsuA:
11.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXM_A_IMNA2001_1
(SERUM ALBUMIN)		 1wsu SELENOCYSTEINE-SPECI
FIC ELONGATION
FACTOR
(Moorella
thermoacetica) 		4 / 8 SER A 589
PHE A 593
ALA A 598
LEU A 613
 None
 0.88A 2bxmA-1wsuA:
undetectable		 2bxmA-1wsuA:
12.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DC3_A_ADNA401_2
(ADENOSINE KINASE)		 1wsu SELENOCYSTEINE-SPECI
FIC ELONGATION
FACTOR
(Moorella
thermoacetica) 		4 / 4 LEU A 577
ILE A 584
GLY A 578
PHE A 621
 None
 1.07A 4dc3A-1wsuA:
undetectable		 4dc3A-1wsuA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZME_A_ADNA1002_1
(MYOSIN HEAVY CHAIN
KINASE A)		 1wsu SELENOCYSTEINE-SPECI
FIC ELONGATION
FACTOR
(Moorella
thermoacetica) 		5 / 11 PHE A 593
ALA A 588
LEU A 613
LEU A 616
PHE A 621
 None
 1.15A 4zmeA-1wsuA:
undetectable		 4zmeA-1wsuA:
17.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZME_B_ADNB902_1
(MYOSIN HEAVY CHAIN
KINASE A)		 1wsu SELENOCYSTEINE-SPECI
FIC ELONGATION
FACTOR
(Moorella
thermoacetica) 		5 / 10 PHE A 593
ALA A 588
LEU A 577
LEU A 616
PHE A 621
 None
 1.27A 4zmeB-1wsuA:
undetectable		 4zmeB-1wsuA:
17.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZME_B_ADNB902_1
(MYOSIN HEAVY CHAIN
KINASE A)		 1wsu SELENOCYSTEINE-SPECI
FIC ELONGATION
FACTOR
(Moorella
thermoacetica) 		5 / 10 PHE A 593
ALA A 588
LEU A 613
LEU A 616
PHE A 621
 None
 1.15A 4zmeB-1wsuA:
undetectable		 4zmeB-1wsuA:
17.08