SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1wt9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_D_DVAD8_0
(GRAMICIDIN A)		 1wt9 ANTICOAGULANT
PROTEIN-B
(Deinagkistrodon
acutus) 		3 / 3 TRP B  65
VAL B  40
TRP B  23
 None
 1.16A 1c4dC-1wt9B:
undetectable
1c4dD-1wt9B:
undetectable		 1c4dC-1wt9B:
13.75
1c4dD-1wt9B:
13.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_D_DVAD8_0
(GRAMICIDIN A)		 1wt9 ANTICOAGULANT
PROTEIN-B
(Deinagkistrodon
acutus) 		3 / 3 TRP B  65
VAL B 118
TRP B  23
 None
 1.29A 1c4dC-1wt9B:
undetectable
1c4dD-1wt9B:
undetectable		 1c4dC-1wt9B:
13.75
1c4dD-1wt9B:
13.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GVC_B_MMZB501_1
(MONOOXYGENASE)		 1wt9 ANTICOAGULANT
PROTEIN-B
(Deinagkistrodon
acutus) 		3 / 3 ASN B 103
TYR B  98
SER B 101
 None
 0.93A 2gvcB-1wt9B:
undetectable		 2gvcB-1wt9B:
13.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GVC_E_MMZE501_1
(MONOOXYGENASE)		 1wt9 ANTICOAGULANT
PROTEIN-B
(Deinagkistrodon
acutus) 		3 / 3 ASN B 103
TYR B  98
SER B 101
 None
 0.88A 2gvcE-1wt9B:
undetectable		 2gvcE-1wt9B:
13.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_A_DVAA8_0
(GRAMICIDIN A)		 1wt9 ANTICOAGULANT
PROTEIN-B
(Deinagkistrodon
acutus) 		3 / 3 VAL B 118
TRP B  23
TRP B  65
 None
 1.17A 2xdcA-1wt9B:
undetectable
2xdcB-1wt9B:
undetectable		 2xdcA-1wt9B:
13.75
2xdcB-1wt9B:
13.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_A_DVAA8_0
(GRAMICIDIN A)		 1wt9 ANTICOAGULANT
PROTEIN-B
(Deinagkistrodon
acutus) 		3 / 3 VAL B 118
TRP B  65
TRP B  23
 None
 1.45A 2xdcA-1wt9B:
undetectable
2xdcB-1wt9B:
undetectable		 2xdcA-1wt9B:
13.75
2xdcB-1wt9B:
13.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_B_DVAB8_0
(GRAMICIDIN A)		 1wt9 ANTICOAGULANT
PROTEIN-B
(Deinagkistrodon
acutus) 		3 / 3 TRP B  23
VAL B 118
TRP B  65
 None
 1.44A 2xdcA-1wt9B:
undetectable
2xdcB-1wt9B:
undetectable		 2xdcA-1wt9B:
13.75
2xdcB-1wt9B:
13.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_B_DVAB8_0
(GRAMICIDIN A)		 1wt9 ANTICOAGULANT
PROTEIN-B
(Deinagkistrodon
acutus) 		3 / 3 TRP B  65
VAL B 118
TRP B  23
 None
 1.19A 2xdcA-1wt9B:
undetectable
2xdcB-1wt9B:
undetectable		 2xdcA-1wt9B:
13.75
2xdcB-1wt9B:
13.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_C_DVAC8_0
(GRAMICIDIN A)		 1wt9 ANTICOAGULANT
PROTEIN-B
(Deinagkistrodon
acutus) 		3 / 3 VAL B 118
TRP B  23
TRP B  65
 None
 1.20A 2xdcC-1wt9B:
undetectable
2xdcD-1wt9B:
undetectable		 2xdcC-1wt9B:
13.75
2xdcD-1wt9B:
13.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_D_DVAD8_0
(GRAMICIDIN A)		 1wt9 ANTICOAGULANT
PROTEIN-B
(Deinagkistrodon
acutus) 		3 / 3 TRP B  65
VAL B 118
TRP B  23
 None
 1.07A 2xdcC-1wt9B:
undetectable
2xdcD-1wt9B:
undetectable		 2xdcC-1wt9B:
13.75
2xdcD-1wt9B:
13.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XDC_F_DVAF8_0
(GRAMICIDIN A)		 1wt9 ANTICOAGULANT
PROTEIN-B
(Deinagkistrodon
acutus) 		3 / 3 TRP B  65
VAL B 118
TRP B  23
 None
 1.10A 2xdcE-1wt9B:
undetectable
2xdcF-1wt9B:
undetectable		 2xdcE-1wt9B:
13.75
2xdcF-1wt9B:
13.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y5M_A_DVAA8_0
(VAL-GRAMICIDIN A)		 1wt9 ANTICOAGULANT
PROTEIN-B
(Deinagkistrodon
acutus) 		3 / 3 VAL B 118
TRP B  23
TRP B  65
 None
 1.17A 2y5mA-1wt9B:
undetectable
2y5mB-1wt9B:
undetectable		 2y5mA-1wt9B:
13.75
2y5mB-1wt9B:
13.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y5M_A_DVAA8_0
(VAL-GRAMICIDIN A)		 1wt9 ANTICOAGULANT
PROTEIN-B
(Deinagkistrodon
acutus) 		3 / 3 VAL B 118
TRP B  65
TRP B  23
 None
 1.44A 2y5mA-1wt9B:
undetectable
2y5mB-1wt9B:
undetectable		 2y5mA-1wt9B:
13.75
2y5mB-1wt9B:
13.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y5M_F_DVAF8_0
(VAL-GRAMICIDIN A)		 1wt9 ANTICOAGULANT
PROTEIN-B
(Deinagkistrodon
acutus) 		3 / 3 TRP B  65
VAL B 118
TRP B  23
 None
 1.08A 2y5mE-1wt9B:
undetectable
2y5mF-1wt9B:
undetectable		 2y5mE-1wt9B:
13.75
2y5mF-1wt9B:
13.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6N_A_DVAA8_0
(VAL-GRAMICIDIN A)		 1wt9 ANTICOAGULANT
PROTEIN-B
(Deinagkistrodon
acutus) 		3 / 3 VAL B 118
TRP B  23
TRP B  65
 None
 1.16A 2y6nA-1wt9B:
undetectable
2y6nB-1wt9B:
undetectable		 2y6nA-1wt9B:
13.75
2y6nB-1wt9B:
13.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6N_A_DVAA8_0
(VAL-GRAMICIDIN A)		 1wt9 ANTICOAGULANT
PROTEIN-B
(Deinagkistrodon
acutus) 		3 / 3 VAL B 118
TRP B  65
TRP B  23
 None
 1.45A 2y6nA-1wt9B:
undetectable
2y6nB-1wt9B:
undetectable		 2y6nA-1wt9B:
13.75
2y6nB-1wt9B:
13.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6N_B_DVAB8_0
(VAL-GRAMICIDIN A)		 1wt9 ANTICOAGULANT
PROTEIN-B
(Deinagkistrodon
acutus) 		3 / 3 TRP B  23
VAL B 118
TRP B  65
 None
 1.44A 2y6nA-1wt9B:
undetectable
2y6nB-1wt9B:
undetectable		 2y6nA-1wt9B:
13.75
2y6nB-1wt9B:
13.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6N_B_DVAB8_0
(VAL-GRAMICIDIN A)		 1wt9 ANTICOAGULANT
PROTEIN-B
(Deinagkistrodon
acutus) 		3 / 3 TRP B  65
VAL B 118
TRP B  23
 None
 1.18A 2y6nA-1wt9B:
undetectable
2y6nB-1wt9B:
undetectable		 2y6nA-1wt9B:
13.75
2y6nB-1wt9B:
13.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6N_D_DVAD8_0
(VAL-GRAMICIDIN A)		 1wt9 ANTICOAGULANT
PROTEIN-B
(Deinagkistrodon
acutus) 		3 / 3 TRP B  65
VAL B 118
TRP B  23
 None
 1.05A 2y6nC-1wt9B:
undetectable
2y6nD-1wt9B:
undetectable		 2y6nC-1wt9B:
13.75
2y6nD-1wt9B:
13.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6N_F_DVAF8_0
(VAL-GRAMICIDIN A)		 1wt9 ANTICOAGULANT
PROTEIN-B
(Deinagkistrodon
acutus) 		3 / 3 TRP B  65
VAL B 118
TRP B  23
 None
 1.06A 2y6nE-1wt9B:
undetectable
2y6nF-1wt9B:
undetectable		 2y6nE-1wt9B:
13.75
2y6nF-1wt9B:
13.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQ8_A_DVAA8_0
(VAL-GRAMICIDIN A)		 1wt9 ANTICOAGULANT
PROTEIN-B
(Deinagkistrodon
acutus) 		3 / 3 VAL B 118
TRP B  23
TRP B  65
 None
 1.15A 3zq8A-1wt9B:
undetectable
3zq8B-1wt9B:
undetectable		 3zq8A-1wt9B:
13.75
3zq8B-1wt9B:
13.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQ8_D_DVAD8_0
(VAL-GRAMICIDIN A)		 1wt9 ANTICOAGULANT
PROTEIN-B
(Deinagkistrodon
acutus) 		3 / 3 TRP B  65
VAL B  40
TRP B  23
 None
 0.96A 3zq8C-1wt9B:
undetectable
3zq8D-1wt9B:
undetectable		 3zq8C-1wt9B:
13.75
3zq8D-1wt9B:
13.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I00_A_ZMRA509_2
(NEURAMINIDASE)		 1wt9 ANTICOAGULANT
PROTEIN-B
(Deinagkistrodon
acutus) 		4 / 5 LEU B  39
TRP B  65
ILE B  63
ASN B 103
 None
 1.48A 4i00A-1wt9B:
undetectable		 4i00A-1wt9B:
15.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NWW_A_ACAA18_2
(SCRFP-TAG,GP41)		 1wt9 ANTICOAGULANT
PROTEIN-B
(Deinagkistrodon
acutus) 		3 / 3 LYS B  70
TRP B  72
SER B  69
 None
 1.15A 5nwwA-1wt9B:
undetectable		 5nwwA-1wt9B:
21.82