SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1wtd'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DFO_A_FFOA1002_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 1wtd ECOO109IR
(Escherichia
coli) 		5 / 12 GLY A  86
HIS A 111
LEU A 123
VAL A 159
SER A 205
 None
 1.09A 1dfoA-1wtdA:
undetectable		 1dfoA-1wtdA:
23.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DFO_B_FFOB2002_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 1wtd ECOO109IR
(Escherichia
coli) 		5 / 12 GLY A  86
HIS A 111
LEU A 123
VAL A 159
SER A 205
 None
 1.09A 1dfoB-1wtdA:
undetectable		 1dfoB-1wtdA:
23.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DFO_C_FFOC3002_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 1wtd ECOO109IR
(Escherichia
coli) 		5 / 12 GLY A  86
HIS A 111
LEU A 123
VAL A 159
SER A 205
 None
 1.09A 1dfoC-1wtdA:
undetectable		 1dfoC-1wtdA:
23.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DFO_D_FFOD4002_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 1wtd ECOO109IR
(Escherichia
coli) 		5 / 12 GLY A  86
HIS A 111
LEU A 123
VAL A 159
SER A 205
 None
 1.09A 1dfoD-1wtdA:
undetectable		 1dfoD-1wtdA:
23.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_A_FFOA1293_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 1wtd ECOO109IR
(Escherichia
coli) 		5 / 12 GLY A  86
HIS A 111
LEU A 123
VAL A 159
SER A 205
 None
 1.07A 1eqbA-1wtdA:
undetectable		 1eqbA-1wtdA:
23.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_B_FFOB2293_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 1wtd ECOO109IR
(Escherichia
coli) 		5 / 12 GLY A  86
HIS A 111
LEU A 123
VAL A 159
SER A 205
 None
 1.07A 1eqbB-1wtdA:
undetectable		 1eqbB-1wtdA:
23.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_C_FFOC3293_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 1wtd ECOO109IR
(Escherichia
coli) 		5 / 12 GLY A  86
HIS A 111
LEU A 123
VAL A 159
SER A 205
 None
 1.07A 1eqbC-1wtdA:
undetectable		 1eqbC-1wtdA:
23.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_D_FFOD4293_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 1wtd ECOO109IR
(Escherichia
coli) 		5 / 12 GLY A  86
HIS A 111
LEU A 123
VAL A 159
SER A 205
 None
 1.07A 1eqbD-1wtdA:
undetectable		 1eqbD-1wtdA:
23.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_C_NCAC339_0
(ADP-RIBOSYL CYCLASE)		 1wtd ECOO109IR
(Escherichia
coli) 		3 / 3 GLU A 211
ASN A 208
TRP A 217
 None
 1.24A 1r15C-1wtdA:
2.6		 1r15C-1wtdA:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_D_NCAD349_0
(ADP-RIBOSYL CYCLASE)		 1wtd ECOO109IR
(Escherichia
coli) 		3 / 3 GLU A 211
ASN A 208
TRP A 217
 None
 1.22A 1r15D-1wtdA:
2.5		 1r15D-1wtdA:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_E_NCAE359_0
(ADP-RIBOSYL CYCLASE)		 1wtd ECOO109IR
(Escherichia
coli) 		3 / 3 GLU A 211
ASN A 208
TRP A 217
 None
 1.21A 1r15E-1wtdA:
2.6		 1r15E-1wtdA:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_F_NCAF369_0
(ADP-RIBOSYL CYCLASE)		 1wtd ECOO109IR
(Escherichia
coli) 		3 / 3 GLU A 211
ASN A 208
TRP A 217
 None
 1.22A 1r15F-1wtdA:
2.6		 1r15F-1wtdA:
23.23