SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1wuf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MX1_D_THAD4_2
(LIVER
CARBOXYLESTERASE I)		 1wuf HYPOTHETICAL PROTEIN
LIN2664
(Listeria
innocua) 		3 / 3 PHE A1091
LEU A1076
MET A1001
 None
 0.89A 1mx1D-1wufA:
undetectable		 1mx1D-1wufA:
23.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NW3_A_SAMA500_0
(HISTONE
METHYLTRANSFERASE
DOT1L)		 1wuf HYPOTHETICAL PROTEIN
LIN2664
(Listeria
innocua) 		5 / 12 VAL A1350
ALA A1011
PHE A1324
LEU A1015
PHE A1333
 None
 1.21A 1nw3A-1wufA:
undetectable		 1nw3A-1wufA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SQ5_D_PAUD6004_0
(PANTOTHENATE KINASE)		 1wuf HYPOTHETICAL PROTEIN
LIN2664
(Listeria
innocua) 		5 / 10 VAL A1297
ASP A1327
LEU A1013
TYR A1045
ILE A1009
 None
 1.32A 1sq5D-1wufA:
0.0		 1sq5D-1wufA:
23.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V8B_B_ADNB1502_2
(ADENOSYLHOMOCYSTEINA
SE)		 1wuf HYPOTHETICAL PROTEIN
LIN2664
(Listeria
innocua) 		3 / 3 GLU A1240
GLU A1098
LEU A1262
 MG  A5001 (-3.1A)
None
None
 0.76A 1v8bB-1wufA:
undetectable		 1v8bB-1wufA:
23.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VQ1_A_SAMA301_1
(N5-GLUTAMINE
METHYLTRANSFERASE,
HEMK)		 1wuf HYPOTHETICAL PROTEIN
LIN2664
(Listeria
innocua) 		3 / 3 GLY A1347
ASP A1110
ASN A1345
 None
 0.59A 1vq1A-1wufA:
undetectable		 1vq1A-1wufA:
23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)		 1wuf HYPOTHETICAL PROTEIN
LIN2664
(Listeria
innocua) 		5 / 12 LEU A1264
LEU A1120
ALA A1121
ILE A1124
ALA A1306
 None
 1.15A 2bxpA-1wufA:
undetectable		 2bxpA-1wufA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IX9_A_MTXA200_1
(DIHYDROFOLATE
REDUCTASE)		 1wuf HYPOTHETICAL PROTEIN
LIN2664
(Listeria
innocua) 		5 / 12 ALA A1006
LEU A1369
GLN A1071
LEU A1090
VAL A1108
 None
 1.20A 3ix9A-1wufA:
undetectable		 3ix9A-1wufA:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QL3_A_FOLA161_0
(DIHYDROFOLATE
REDUCTASE)		 1wuf HYPOTHETICAL PROTEIN
LIN2664
(Listeria
innocua) 		5 / 12 ILE A1236
ALA A1259
LYS A1233
ARG A1178
ILE A1213
 None
 1.05A 3ql3A-1wufA:
undetectable		 3ql3A-1wufA:
17.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9T_C_BEZC264_0
(ECHA1_1)		 1wuf HYPOTHETICAL PROTEIN
LIN2664
(Listeria
innocua) 		4 / 5 ALA A1265
GLU A1059
GLU A1098
ALA A1100
 None
 1.44A 3r9tC-1wufA:
undetectable		 3r9tC-1wufA:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYE_B_YTZB902_1
(DIHYDROPTEROATE
SYNTHASE)		 1wuf HYPOTHETICAL PROTEIN
LIN2664
(Listeria
innocua) 		3 / 3 PHE A1051
LYS A1029
SER A1028
 None
 1.35A 3tyeB-1wufA:
6.5		 3tyeB-1wufA:
24.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VHU_A_SNLA1001_1
(MINERALOCORTICOID
RECEPTOR)		 1wuf HYPOTHETICAL PROTEIN
LIN2664
(Listeria
innocua) 		5 / 12 LEU A1147
ASN A1151
GLN A1156
ARG A1322
LEU A1184
 None
 1.47A 3vhuA-1wufA:
undetectable		 3vhuA-1wufA:
22.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A79_A_P1BA601_1
(AMINE OXIDASE
[FLAVIN-CONTAINING]
B)		 1wuf HYPOTHETICAL PROTEIN
LIN2664
(Listeria
innocua) 		5 / 12 LEU A1210
LEU A1202
ILE A1171
ILE A1165
TYR A1194
 None
 1.20A 4a79A-1wufA:
undetectable		 4a79A-1wufA:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A7A_A_RGZA601_1
(AMINE OXIDASE
[FLAVIN-CONTAINING]
B)		 1wuf HYPOTHETICAL PROTEIN
LIN2664
(Listeria
innocua) 		5 / 11 LEU A1210
LEU A1202
ILE A1171
ILE A1165
TYR A1194
 None
 1.23A 4a7aA-1wufA:
undetectable		 4a7aA-1wufA:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AX8_A_SAMA1474_0
(WBDD)		 1wuf HYPOTHETICAL PROTEIN
LIN2664
(Listeria
innocua) 		5 / 12 GLY A1046
ILE A1034
ILE A1033
VAL A1297
ILE A1328
 None
 0.95A 4ax8A-1wufA:
undetectable		 4ax8A-1wufA:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AZV_A_SAMA1474_0
(WBDD)		 1wuf HYPOTHETICAL PROTEIN
LIN2664
(Listeria
innocua) 		5 / 12 GLY A1046
ILE A1034
ILE A1033
VAL A1297
ILE A1328
 None
 0.92A 4azvA-1wufA:
undetectable		 4azvA-1wufA:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DM8_A_REAA501_1
(RETINOIC ACID
RECEPTOR BETA)		 1wuf HYPOTHETICAL PROTEIN
LIN2664
(Listeria
innocua) 		5 / 11 PHE A1091
LEU A1036
ILE A1034
LEU A1073
ILE A1081
 None
 1.18A 4dm8A-1wufA:
undetectable		 4dm8A-1wufA:
26.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G19_D_ACTD302_0
(GLUTATHIONE
TRANSFERASE GTE1)		 1wuf HYPOTHETICAL PROTEIN
LIN2664
(Listeria
innocua) 		3 / 3 TYR A1153
PHE A1323
ARG A1322
 None
 1.19A 4g19D-1wufA:
undetectable		 4g19D-1wufA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R3A_B_RBFB402_2
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 1wuf HYPOTHETICAL PROTEIN
LIN2664
(Listeria
innocua) 		5 / 12 LEU A1262
ALA A1121
ILE A1124
LEU A1106
GLY A1269
 None
 0.97A 4r3aB-1wufA:
undetectable		 4r3aB-1wufA:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UDA_A_DEXA1985_1
(MINERALOCORTICOID
RECEPTOR)		 1wuf HYPOTHETICAL PROTEIN
LIN2664
(Listeria
innocua) 		5 / 12 LEU A1147
ASN A1151
GLN A1156
ARG A1322
LEU A1184
 None
 1.48A 4udaA-1wufA:
undetectable		 4udaA-1wufA:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZJO_D_ERYD1101_0
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 1wuf HYPOTHETICAL PROTEIN
LIN2664
(Listeria
innocua) 		5 / 11 SER A1022
THR A1021
GLU A1049
ASP A1239
GLU A1240
 None
None
None
MG  A5001 (-3.5A)
MG  A5001 (-3.1A)
 1.49A 4zjoD-1wufA:
undetectable		 4zjoD-1wufA:
17.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FXT_A_0LAA1376_1
(DNA POLYMERASE III
SUBUNIT BETA)		 1wuf HYPOTHETICAL PROTEIN
LIN2664
(Listeria
innocua) 		4 / 7 LYS A1027
LEU A1026
THR A1021
PRO A1052
 None
 1.02A 5fxtA-1wufA:
undetectable		 5fxtA-1wufA:
23.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_A_ADNA501_2
(ADENOSYLHOMOCYSTEINA
SE)		 1wuf HYPOTHETICAL PROTEIN
LIN2664
(Listeria
innocua) 		4 / 5 GLU A1240
THR A1057
GLU A1098
LEU A1262
 MG  A5001 (-3.1A)
None
None
None
 1.24A 5hm8A-1wufA:
undetectable		 5hm8A-1wufA:
23.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_B_ADNB501_2
(ADENOSYLHOMOCYSTEINA
SE)		 1wuf HYPOTHETICAL PROTEIN
LIN2664
(Listeria
innocua) 		4 / 5 GLU A1240
THR A1057
GLU A1098
LEU A1262
 MG  A5001 (-3.1A)
None
None
None
 1.24A 5hm8B-1wufA:
undetectable		 5hm8B-1wufA:
23.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_C_ADNC501_2
(ADENOSYLHOMOCYSTEINA
SE)		 1wuf HYPOTHETICAL PROTEIN
LIN2664
(Listeria
innocua) 		4 / 5 GLU A1240
THR A1057
GLU A1098
LEU A1262
 MG  A5001 (-3.1A)
None
None
None
 1.23A 5hm8C-1wufA:
undetectable		 5hm8C-1wufA:
23.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_D_ADND501_2
(ADENOSYLHOMOCYSTEINA
SE)		 1wuf HYPOTHETICAL PROTEIN
LIN2664
(Listeria
innocua) 		4 / 5 GLU A1240
THR A1057
GLU A1098
LEU A1262
 MG  A5001 (-3.1A)
None
None
None
 1.24A 5hm8D-1wufA:
undetectable		 5hm8D-1wufA:
23.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_E_ADNE501_2
(ADENOSYLHOMOCYSTEINA
SE)		 1wuf HYPOTHETICAL PROTEIN
LIN2664
(Listeria
innocua) 		4 / 5 GLU A1240
THR A1057
GLU A1098
LEU A1262
 MG  A5001 (-3.1A)
None
None
None
 1.24A 5hm8E-1wufA:
undetectable		 5hm8E-1wufA:
23.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_F_ADNF501_2
(ADENOSYLHOMOCYSTEINA
SE)		 1wuf HYPOTHETICAL PROTEIN
LIN2664
(Listeria
innocua) 		4 / 5 GLU A1240
THR A1057
GLU A1098
LEU A1262
 MG  A5001 (-3.1A)
None
None
None
 1.24A 5hm8F-1wufA:
undetectable		 5hm8F-1wufA:
23.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_H_ADNH501_2
(ADENOSYLHOMOCYSTEINA
SE)		 1wuf HYPOTHETICAL PROTEIN
LIN2664
(Listeria
innocua) 		4 / 5 GLU A1240
THR A1057
GLU A1098
LEU A1262
 MG  A5001 (-3.1A)
None
None
None
 1.24A 5hm8H-1wufA:
undetectable		 5hm8H-1wufA:
23.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KKL_B_SAMB8009_0
(PUTATIVE
UNCHARACTERIZED
PROTEIN,HISTONE H3.1
PEPTIDE,ZINC FINGER
DOMAIN-CONTAINING
PROTEIN)		 1wuf HYPOTHETICAL PROTEIN
LIN2664
(Listeria
innocua) 		5 / 12 LEU A1305
GLY A1290
ASN A1302
HIS A1301
LEU A1106
 None
 1.41A 5kklB-1wufA:
undetectable		 5kklB-1wufA:
18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_B_CVIB301_0
(REGULATORY PROTEIN
TETR)		 1wuf HYPOTHETICAL PROTEIN
LIN2664
(Listeria
innocua) 		5 / 12 GLN A1071
GLU A1059
LEU A1066
ILE A1065
VAL A1104
 None
 1.29A 5vlmB-1wufA:
undetectable		 5vlmB-1wufA:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOP_A_C2FA3001_1
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 1wuf HYPOTHETICAL PROTEIN
LIN2664
(Listeria
innocua) 		3 / 3 ASP A1239
ASN A1261
ASP A1316
 MG  A5001 (-3.5A)
None
None
 0.80A 5vopA-1wufA:
9.6		 5vopA-1wufA:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOP_B_C2FB3001_1
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 1wuf HYPOTHETICAL PROTEIN
LIN2664
(Listeria
innocua) 		3 / 3 ASP A1239
ASN A1261
ASP A1316
 MG  A5001 (-3.5A)
None
None
 0.76A 5vopB-1wufA:
8.8		 5vopB-1wufA:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YK2_A_ERYA501_0
(PROBABLE CONSERVED
ATP-BINDING PROTEIN
ABC TRANSPORTER)		 1wuf HYPOTHETICAL PROTEIN
LIN2664
(Listeria
innocua) 		5 / 11 GLU A1310
GLY A1315
ALA A1306
ILE A1131
VAL A1133
 None
 1.09A 5yk2A-1wufA:
undetectable		 5yk2A-1wufA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AZ3_1_PAR11802_1
(RRNA ALPHA
RIBOSOMAL PROTEIN
UL4
RIBOSOMAL PROTEIN
UL15
RIBOSOMAL PROTEIN
EL15)		 1wuf HYPOTHETICAL PROTEIN
LIN2664
(Listeria
innocua) 		3 / 3 ARG A1266
LYS A1162
ARG A1243
 None
 1.38A 6az3C-1wufA:
0.0
6az3L-1wufA:
0.0
6az3M-1wufA:
undetectable		 6az3C-1wufA:
11.52
6az3L-1wufA:
11.14
6az3M-1wufA:
12.40