SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1wv9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1ZQ9_B_SAMB4001_0 (PROBABLE DIMETHYLADENOSINE TRANSFERASE)	1wv9	RHODANESE HOMOLOG TT1651 (Thermus thermophilus)	5 / 12	GLY A 63 GLY A 86 LEU A 58 LEU A 83 VAL A 68	None	1.02A	1zq9B-1wv9A: undetectable	1zq9B-1wv9A: 16.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2VCV_D_ASDD1224_1 (GLUTATHIONE S-TRANSFERASE A3)	1wv9	RHODANESE HOMOLOG TT1651 (Thermus thermophilus)	5 / 9	PRO A 6 LEU A 9 ALA A 89 LEU A 83 PHE A 34	None	1.21A	2vcvD-1wv9A: undetectable	2vcvD-1wv9A: 20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2VCV_E_ASDE1224_1 (GLUTATHIONE S-TRANSFERASE A3)	1wv9	RHODANESE HOMOLOG TT1651 (Thermus thermophilus)	5 / 9	PRO A 6 LEU A 9 ALA A 89 LEU A 83 PHE A 34	None	1.23A	2vcvE-1wv9A: undetectable	2vcvE-1wv9A: 20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2VCV_I_ASDI1224_1 (GLUTATHIONE S-TRANSFERASE A3)	1wv9	RHODANESE HOMOLOG TT1651 (Thermus thermophilus)	5 / 9	PRO A 6 LEU A 9 ALA A 89 LEU A 83 PHE A 34	None	1.19A	2vcvI-1wv9A: undetectable	2vcvI-1wv9A: 20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FGZ_B_CQAB302_0 (PHOSPHOETHANOLAMINE N-METHYLTRANSFERASE)	1wv9	RHODANESE HOMOLOG TT1651 (Thermus thermophilus)	4 / 8	GLU A 74 GLU A 79 TYR A 78 ARG A 53	None	0.97A	4fgzA-1wv9A: undetectable 4fgzB-1wv9A: undetectable	4fgzA-1wv9A: 16.03 4fgzB-1wv9A: 16.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4Z4C_A_IPHA904_0 (PROTEIN ARGONAUTE-2)	1wv9	RHODANESE HOMOLOG TT1651 (Thermus thermophilus)	4 / 6	PRO A 52 LEU A 73 GLU A 76 TYR A 78	None	1.28A	4z4cA-1wv9A: undetectable	4z4cA-1wv9A: 9.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4Z4G_A_IPHA903_0 (PROTEIN ARGONAUTE-2)	1wv9	RHODANESE HOMOLOG TT1651 (Thermus thermophilus)	4 / 6	LEU A 56 PRO A 52 GLU A 76 TYR A 78	None	1.28A	4z4gA-1wv9A: undetectable	4z4gA-1wv9A: 9.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6G2P_B_TRPB502_0 (FLAVIN-DEPENDENT L-TRYPTOPHAN OXIDASE VIOA)	1wv9	RHODANESE HOMOLOG TT1651 (Thermus thermophilus)	5 / 10	ALA A 69 LEU A 58 LEU A 56 TYR A 78 VAL A 20	None	1.38A	6g2pB-1wv9A: undetectable	6g2pB-1wv9A: 14.29

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1ZQ9_B_SAMB4001_0","PROBABLE DIMETHYLADENOSINE TRANSFERASE","1wv9","RHODANESE HOMOLOG TT1651","Thermus thermophilus",5,"GLY A  63;GLY A  86;LEU A  58;LEU A  83;VAL A  68","None","1.02A","1zq9B-1wv9A:undetectable","1zq9B-1wv9A:16.23"],["2VCV_D_ASDD1224_1","GLUTATHIONE S-TRANSFERASE A3","1wv9","RHODANESE HOMOLOG TT1651","Thermus thermophilus",5,"PRO A   6;LEU A   9;ALA A  89;LEU A  83;PHE A  34","None","1.21A","2vcvD-1wv9A:undetectable","2vcvD-1wv9A:20.41"],["2VCV_E_ASDE1224_1","GLUTATHIONE S-TRANSFERASE A3","1wv9","RHODANESE HOMOLOG TT1651","Thermus thermophilus",5,"PRO A   6;LEU A   9;ALA A  89;LEU A  83;PHE A  34","None","1.23A","2vcvE-1wv9A:undetectable","2vcvE-1wv9A:20.41"],["2VCV_I_ASDI1224_1","GLUTATHIONE S-TRANSFERASE A3","1wv9","RHODANESE HOMOLOG TT1651","Thermus thermophilus",5,"PRO A   6;LEU A   9;ALA A  89;LEU A  83;PHE A  34","None","1.19A","2vcvI-1wv9A:undetectable","2vcvI-1wv9A:20.41"],["4FGZ_B_CQAB302_0","PHOSPHOETHANOLAMINE N-METHYLTRANSFERASE","1wv9","RHODANESE HOMOLOG TT1651","Thermus thermophilus",4,"GLU A  74;GLU A  79;TYR A  78;ARG A  53","None","0.97A","4fgzA-1wv9A:undetectable;4fgzB-1wv9A:undetectable","4fgzA-1wv9A:16.03;4fgzB-1wv9A:16.03"],["4Z4C_A_IPHA904_0","PROTEIN ARGONAUTE-2","1wv9","RHODANESE HOMOLOG TT1651","Thermus thermophilus",4,"PRO A  52;LEU A  73;GLU A  76;TYR A  78","None","1.28A","4z4cA-1wv9A:undetectable","4z4cA-1wv9A:9.72"],["4Z4G_A_IPHA903_0","PROTEIN ARGONAUTE-2","1wv9","RHODANESE HOMOLOG TT1651","Thermus thermophilus",4,"LEU A  56;PRO A  52;GLU A  76;TYR A  78","None","1.28A","4z4gA-1wv9A:undetectable","4z4gA-1wv9A:9.72"],["6G2P_B_TRPB502_0","FLAVIN-DEPENDENT L-TRYPTOPHAN OXIDASE VIOA","1wv9","RHODANESE HOMOLOG TT1651","Thermus thermophilus",5,"ALA A  69;LEU A  58;LEU A  56;TYR A  78;VAL A  20","None","1.38A","6g2pB-1wv9A:undetectable","6g2pB-1wv9A:14.29"]]