SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1wvc'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO5_B_CHDB503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1wvc GLUCOSE-1-PHOSPHATE
CYTIDYLYLTRANSFERASE
(Salmonella
enterica) 		3 / 3 LEU A 214
PRO A 213
LEU A 217
 None
 0.58A 2po5B-1wvcA:
2.3		 2po5B-1wvcA:
19.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO7_B_CHDB503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1wvc GLUCOSE-1-PHOSPHATE
CYTIDYLYLTRANSFERASE
(Salmonella
enterica) 		3 / 3 LEU A 214
PRO A 213
LEU A 217
 None
 0.57A 2po7B-1wvcA:
2.4		 2po7B-1wvcA:
19.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCR_A_CHDA4_0
(FERROCHELATASE,
MITOCHONDRIAL)		 1wvc GLUCOSE-1-PHOSPHATE
CYTIDYLYLTRANSFERASE
(Salmonella
enterica) 		3 / 3 LEU A 214
PRO A 213
LEU A 217
 None
 0.56A 3hcrA-1wvcA:
2.4		 3hcrA-1wvcA:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUM_A_IMNA502_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1wvc GLUCOSE-1-PHOSPHATE
CYTIDYLYLTRANSFERASE
(Salmonella
enterica) 		4 / 7 GLU A 117
CYH A  55
LEU A  36
ILE A  52
 None
 0.92A 4xumA-1wvcA:
undetectable		 4xumA-1wvcA:
22.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HS6_A_J3ZA302_1
(17-BETA-HYDROXYSTERO
ID DEHYDROGENASE 14)		 1wvc GLUCOSE-1-PHOSPHATE
CYTIDYLYLTRANSFERASE
(Salmonella
enterica) 		4 / 8 HIS A 228
LEU A 136
MET A  42
THR A 257
 None
 1.17A 5hs6A-1wvcA:
2.4		 5hs6A-1wvcA:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGY_A_ERYA403_0
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 1wvc GLUCOSE-1-PHOSPHATE
CYTIDYLYLTRANSFERASE
(Salmonella
enterica) 		5 / 12 GLY A 190
HIS A 145
GLU A 123
PHE A 144
ILE A  48
 None
 1.08A 5igyA-1wvcA:
undetectable		 5igyA-1wvcA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7P_A_ACRA1421_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)		 1wvc GLUCOSE-1-PHOSPHATE
CYTIDYLYLTRANSFERASE
(Salmonella
enterica) 		4 / 5 MET A  42
TYR A 129
GLY A 190
GLY A 189
 None
 1.15A 5x7pA-1wvcA:
undetectable		 5x7pA-1wvcA:
11.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G2P_A_TRPA502_0
(FLAVIN-DEPENDENT
L-TRYPTOPHAN OXIDASE
VIOA)		 1wvc GLUCOSE-1-PHOSPHATE
CYTIDYLYLTRANSFERASE
(Salmonella
enterica) 		4 / 7 TYR A  65
LEU A  99
VAL A  97
TRP A  95
 None
 1.33A 6g2pA-1wvcA:
undetectable		 6g2pA-1wvcA:
21.98