SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1wvh'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R0L_D_ACTD127_0
(PHOSPHOLIPASE A2 CB)		 1wvh TENSIN
(Gallus
gallus) 		4 / 5 PHE A1648
ILE A1729
GLY A1700
CYH A1678
 None
 1.29A 3r0lD-1wvhA:
undetectable		 3r0lD-1wvhA:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EMA_A_BRLA601_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1wvh TENSIN
(Gallus
gallus) 		3 / 3 PHE A1612
VAL A1733
ILE A1729
 None
 0.57A 4emaA-1wvhA:
undetectable		 4emaA-1wvhA:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GRK_A_KTRA713_1
(LACTOTRANSFERRIN)		 1wvh TENSIN
(Gallus
gallus) 		4 / 5 THR A1656
GLY A1654
VAL A1675
PRO A1671
 None
 1.15A 4grkA-1wvhA:
undetectable		 4grkA-1wvhA:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MA7_A_P2ZA301_1
(MAJOR PRION PROTEIN)		 1wvh TENSIN
(Gallus
gallus) 		4 / 8 VAL A1713
TYR A1670
ILE A1655
VAL A1646
 None
 0.93A 4ma7A-1wvhA:
undetectable		 4ma7A-1wvhA:
22.45