SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1wvi'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HPK_A_ACAA80_1
(PLASMINOGEN)		 1wvi PUTATIVE
PHOSPHATASES
INVOLVED IN
N-ACETYL-GLUCOSAMINE
CATABOLISM
(Streptococcus
mutans) 		4 / 6 ASP A1206
ASN A1207
ASP A1009
TYR A1015
 None
 1.06A 1hpkA-1wviA:
undetectable		 1hpkA-1wviA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_E_SC2E1289_1
(FICOLIN-2)		 1wvi PUTATIVE
PHOSPHATASES
INVOLVED IN
N-ACETYL-GLUCOSAMINE
CATABOLISM
(Streptococcus
mutans) 		4 / 6 ASP A1011
ASP A1148
THR A1210
ASP A1009
 None
 1.28A 2j2pE-1wviA:
undetectable
2j2pF-1wviA:
undetectable		 2j2pE-1wviA:
19.08
2j2pF-1wviA:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PYN_A_1UNA1001_3
(PROTEASE RETROPEPSIN)		 1wvi PUTATIVE
PHOSPHATASES
INVOLVED IN
N-ACETYL-GLUCOSAMINE
CATABOLISM
(Streptococcus
mutans) 		3 / 3 ASP A1026
THR A1064
PRO A1065
 None
 0.63A 2pynB-1wviA:
undetectable		 2pynB-1wviA:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q64_B_1UNB1001_4
(PROTEASE RETROPEPSIN)		 1wvi PUTATIVE
PHOSPHATASES
INVOLVED IN
N-ACETYL-GLUCOSAMINE
CATABOLISM
(Streptococcus
mutans) 		3 / 3 ASP A1026
THR A1064
PRO A1065
 None
 0.64A 2q64B-1wviA:
undetectable		 2q64B-1wviA:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QAK_A_1UNA1001_4
(PROTEASE RETROPEPSIN)		 1wvi PUTATIVE
PHOSPHATASES
INVOLVED IN
N-ACETYL-GLUCOSAMINE
CATABOLISM
(Streptococcus
mutans) 		3 / 3 ASP A1026
THR A1064
PRO A1065
 None
 0.60A 2qakB-1wviA:
undetectable		 2qakB-1wviA:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZJ0_A_2FAA500_2
(ADENOSYLHOMOCYSTEINA
SE)		 1wvi PUTATIVE
PHOSPHATASES
INVOLVED IN
N-ACETYL-GLUCOSAMINE
CATABOLISM
(Streptococcus
mutans) 		4 / 5 GLN A1053
THR A1064
THR A1042
LEU A1074
 None
 1.30A 2zj0A-1wviA:
undetectable		 2zj0A-1wviA:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CE6_A_ADNA500_2
(ADENOSYLHOMOCYSTEINA
SE)		 1wvi PUTATIVE
PHOSPHATASES
INVOLVED IN
N-ACETYL-GLUCOSAMINE
CATABOLISM
(Streptococcus
mutans) 		4 / 5 GLN A1053
THR A1064
THR A1042
LEU A1074
 None
 1.29A 3ce6A-1wviA:
4.1		 3ce6A-1wviA:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CE6_C_ADNC500_2
(ADENOSYLHOMOCYSTEINA
SE)		 1wvi PUTATIVE
PHOSPHATASES
INVOLVED IN
N-ACETYL-GLUCOSAMINE
CATABOLISM
(Streptococcus
mutans) 		4 / 5 GLN A1053
THR A1064
THR A1042
LEU A1074
 None
 1.30A 3ce6C-1wviA:
2.7		 3ce6C-1wviA:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HZN_G_ACTG225_0
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 1wvi PUTATIVE
PHOSPHATASES
INVOLVED IN
N-ACETYL-GLUCOSAMINE
CATABOLISM
(Streptococcus
mutans) 		3 / 3 PRO A1065
LEU A1066
GLN A1053
 None
 0.51A 3hznG-1wviA:
undetectable
3hznH-1wviA:
undetectable		 3hznG-1wviA:
22.26
3hznH-1wviA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKG_C_ROCC901_3
(PROTEASE)		 1wvi PUTATIVE
PHOSPHATASES
INVOLVED IN
N-ACETYL-GLUCOSAMINE
CATABOLISM
(Streptococcus
mutans) 		3 / 3 ASP A1026
THR A1064
PRO A1065
 None
 0.66A 3tkgD-1wviA:
undetectable		 3tkgD-1wviA:
25.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOG_A_ML1A302_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 1wvi PUTATIVE
PHOSPHATASES
INVOLVED IN
N-ACETYL-GLUCOSAMINE
CATABOLISM
(Streptococcus
mutans) 		4 / 8 ILE A1202
PHE A1027
GLY A1205
ILE A1212
 None
 0.88A 4qogA-1wviA:
3.4
4qogB-1wviA:
3.4		 4qogA-1wviA:
22.99
4qogB-1wviA:
22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R20_A_AERA602_1
(CYTOCHROME P450
FAMILY 17
POLYPEPTIDE 2)		 1wvi PUTATIVE
PHOSPHATASES
INVOLVED IN
N-ACETYL-GLUCOSAMINE
CATABOLISM
(Streptococcus
mutans) 		4 / 8 ALA A1132
ASN A1146
ILE A1178
GLY A1119
 None
 0.75A 4r20A-1wviA:
undetectable		 4r20A-1wviA:
17.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XJE_A_TOYA202_1
(AADB)		 1wvi PUTATIVE
PHOSPHATASES
INVOLVED IN
N-ACETYL-GLUCOSAMINE
CATABOLISM
(Streptococcus
mutans) 		4 / 8 ASP A1206
ASP A1009
ASP A1211
ILE A1186
 None
 1.05A 4xjeA-1wviA:
undetectable		 4xjeA-1wviA:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BOJ_A_4TXA201_1
(TRANSTHYRETIN)		 1wvi PUTATIVE
PHOSPHATASES
INVOLVED IN
N-ACETYL-GLUCOSAMINE
CATABOLISM
(Streptococcus
mutans) 		4 / 6 LEU A1223
LEU A1246
SER A1247
THR A1227
 None
 1.07A 5bojA-1wviA:
undetectable		 5bojA-1wviA:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BYK_A_OAQA302_0
(SULFOTRANSFERASE)		 1wvi PUTATIVE
PHOSPHATASES
INVOLVED IN
N-ACETYL-GLUCOSAMINE
CATABOLISM
(Streptococcus
mutans) 		5 / 12 ILE A1164
VAL A1116
VAL A1117
LEU A1124
THR A1145
 None
 1.29A 5bykA-1wviA:
undetectable		 5bykA-1wviA:
22.58