SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1wvr'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_W_CHDW4060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 1wvr TRIFLIN
(Protobothrops
flavoviridis) 		4 / 7 ILE A  90
LEU A  21
TYR A 147
THR A 117
 None
 0.98A 1v54N-1wvrA:
undetectable
1v54W-1wvrA:
undetectable		 1v54N-1wvrA:
15.85
1v54W-1wvrA:
14.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 1wvr TRIFLIN
(Protobothrops
flavoviridis) 		4 / 7 ILE A  90
LEU A  21
TYR A 147
THR A 117
 None
 1.03A 3ag2N-1wvrA:
undetectable
3ag2W-1wvrA:
undetectable		 3ag2N-1wvrA:
15.85
3ag2W-1wvrA:
14.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 1wvr TRIFLIN
(Protobothrops
flavoviridis) 		4 / 7 ILE A  90
LEU A  21
TYR A 147
THR A 117
 None
 0.94A 3ag4N-1wvrA:
undetectable
3ag4W-1wvrA:
undetectable		 3ag4N-1wvrA:
15.85
3ag4W-1wvrA:
14.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL9_A_DR7A100_2
(PROTEASE)		 1wvr TRIFLIN
(Protobothrops
flavoviridis) 		5 / 10 GLY A  74
ALA A 150
ILE A 119
PRO A 160
THR A 157
 None
 0.98A 3el9B-1wvrA:
undetectable		 3el9B-1wvrA:
19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1wvr TRIFLIN
(Protobothrops
flavoviridis) 		4 / 6 ILE A  90
LEU A  21
TYR A 147
THR A 117
 None
 1.02A 3wg7A-1wvrA:
undetectable
3wg7J-1wvrA:
undetectable		 3wg7A-1wvrA:
15.85
3wg7J-1wvrA:
14.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AF0_A_MOAA1526_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE)		 1wvr TRIFLIN
(Protobothrops
flavoviridis) 		4 / 8 SER A  62
SER A  61
GLY A  74
GLN A 146
 None
 0.77A 4af0A-1wvrA:
undetectable		 4af0A-1wvrA:
15.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G2Z_A_ID8A711_1
(LACTOTRANSFERRIN)		 1wvr TRIFLIN
(Protobothrops
flavoviridis) 		3 / 3 PRO A  31
TYR A 161
GLY A 164
 None
 0.72A 4g2zA-1wvrA:
undetectable		 4g2zA-1wvrA:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MV7_A_PPFA501_1
(BIOTIN CARBOXYLASE)		 1wvr TRIFLIN
(Protobothrops
flavoviridis) 		4 / 7 ASN A  48
GLN A 146
VAL A 144
GLU A  75
 None
 0.81A 4mv7A-1wvrA:
undetectable		 4mv7A-1wvrA:
17.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1wvr TRIFLIN
(Protobothrops
flavoviridis) 		4 / 6 ILE A  90
LEU A  21
TYR A 147
THR A 117
 None
 1.05A 5b1aN-1wvrA:
undetectable
5b1aW-1wvrA:
undetectable		 5b1aN-1wvrA:
15.85
5b1aW-1wvrA:
14.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1wvr TRIFLIN
(Protobothrops
flavoviridis) 		4 / 7 ILE A  90
LEU A  21
TYR A 147
THR A 117
 None
 0.97A 5xdqA-1wvrA:
undetectable
5xdqJ-1wvrA:
undetectable		 5xdqA-1wvrA:
15.85
5xdqJ-1wvrA:
14.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1wvr TRIFLIN
(Protobothrops
flavoviridis) 		4 / 7 ILE A  90
LEU A  21
TYR A 147
THR A 117
 None
 0.94A 5xdqN-1wvrA:
undetectable
5xdqW-1wvrA:
undetectable		 5xdqN-1wvrA:
15.85
5xdqW-1wvrA:
14.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT VIIA-HEART)		 1wvr TRIFLIN
(Protobothrops
flavoviridis) 		4 / 7 ILE A  90
LEU A  21
TYR A 147
THR A 117
 None
 0.98A 5xdxA-1wvrA:
undetectable
5xdxJ-1wvrA:
undetectable		 5xdxA-1wvrA:
15.85
5xdxJ-1wvrA:
14.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 1wvr TRIFLIN
(Protobothrops
flavoviridis) 		4 / 6 ILE A  90
LEU A  21
TYR A 147
THR A 117
 None
 1.03A 6nmfN-1wvrA:
undetectable
6nmfW-1wvrA:
undetectable		 6nmfN-1wvrA:
15.85
6nmfW-1wvrA:
14.35