SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1wvt'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BX4_A_ADNA350_2
(PROTEIN (ADENOSINE
KINASE))		 1wvt HYPOTHETICAL PROTEIN
ST2180
(Sulfurisphaera
tokodaii) 		3 / 3 LEU A  46
SER A 110
ASN A 163
 None
 0.78A 1bx4A-1wvtA:
undetectable		 1bx4A-1wvtA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9P_B_DESB459_2
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 1wvt HYPOTHETICAL PROTEIN
ST2180
(Sulfurisphaera
tokodaii) 		3 / 3 LEU A 112
HIS A 106
ILE A 107
 None
 0.56A 1s9pB-1wvtA:
undetectable		 1s9pB-1wvtA:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9P_C_DESC500_1
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 1wvt HYPOTHETICAL PROTEIN
ST2180
(Sulfurisphaera
tokodaii) 		5 / 12 LEU A  36
LEU A  33
LEU A  30
ALA A  29
LEU A 129
 None
 0.92A 1s9pC-1wvtA:
undetectable		 1s9pC-1wvtA:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD507_1
(HEMOLYTIC LECTIN
CEL-III)		 1wvt HYPOTHETICAL PROTEIN
ST2180
(Sulfurisphaera
tokodaii) 		4 / 5 GLU A  84
GLY A  82
TYR A 142
ASP A  60
 None
 1.20A 3w9tD-1wvtA:
undetectable		 3w9tD-1wvtA:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD9_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1wvt HYPOTHETICAL PROTEIN
ST2180
(Sulfurisphaera
tokodaii) 		4 / 7 VAL A  80
PHE A  75
HIS A 139
GLU A 137
 None
 1.46A 5ad9A-1wvtA:
undetectable
5ad9B-1wvtA:
undetectable		 5ad9A-1wvtA:
16.75
5ad9B-1wvtA:
16.75