SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1wvv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WYG_A_SALA4005_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 1wvv CHITINASE C
(Streptomyces
griseus) 		5 / 10 LEU A 225
PHE A 140
PHE A  91
ALA A 125
ALA A 137
 None
 1.41A 1wygA-1wvvA:
0.4		 1wygA-1wvvA:
11.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O5Y_H_STRH249_1
(CHIMERIC ANTIBODY
FAB 1E9-DB3)		 1wvv CHITINASE C
(Streptomyces
griseus) 		4 / 7 ASN A 246
GLY A 289
THR A 287
SER A 129
 None
 1.24A 2o5yH-1wvvA:
undetectable
2o5yL-1wvvA:
undetectable		 2o5yH-1wvvA:
22.50
2o5yL-1wvvA:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V7U_A_SAMA1299_0
(5'-FLUORO-5'-DEOXY
ADENOSINE SYNTHETASE)		 1wvv CHITINASE C
(Streptomyces
griseus) 		4 / 8 ASN A 143
PHE A 249
SER A 272
ALA A 139
 None
 1.12A 2v7uA-1wvvA:
undetectable		 2v7uA-1wvvA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KYK_B_IMNB300_1
(LACTOYLGLUTATHIONE
LYASE)		 1wvv CHITINASE C
(Streptomyces
griseus) 		5 / 12 PHE A  98
ALA A  96
GLY A  90
LEU A 118
PHE A 124
 None
 1.23A 4kykA-1wvvA:
undetectable
4kykB-1wvvA:
undetectable		 4kykA-1wvvA:
20.85
4kykB-1wvvA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KPR_A_PAUA404_0
(PANTOTHENATE KINASE
3)		 1wvv CHITINASE C
(Streptomyces
griseus) 		4 / 5 GLU A 251
GLY A 258
SER A 255
GLY A 233
 None
 0.98A 5kprA-1wvvA:
undetectable		 5kprA-1wvvA:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X80_B_SALB203_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR RV2887)		 1wvv CHITINASE C
(Streptomyces
griseus) 		4 / 6 GLY A 224
TYR A 227
LEU A 202
VAL A 213
 None
GOL  A 401 ( 4.5A)
None
None
 0.79A 5x80A-1wvvA:
1.6
5x80B-1wvvA:
1.9		 5x80A-1wvvA:
20.59
5x80B-1wvvA:
20.59