SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1ww6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GAL_A_1GNA998_1
(GALECTIN-7)		 1ww6 GALECTIN
(Agrocybe
cylindracea) 		5 / 6 HIS A  62
ARG A  66
ASN A  75
TRP A  83
GLU A  86
 GAL  A 200 (-4.1A)
BGC  A 201 ( 3.0A)
GAL  A 200 (-3.7A)
GAL  A 200 (-3.6A)
BGC  A 201 ( 3.1A)
 0.58A 3galA-1ww6A:
16.0		 3galA-1ww6A:
23.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GAL_B_1GNB999_1
(GALECTIN-7)		 1ww6 GALECTIN
(Agrocybe
cylindracea) 		5 / 6 HIS A  62
ARG A  66
ASN A  75
TRP A  83
GLU A  86
 GAL  A 200 (-4.1A)
BGC  A 201 ( 3.0A)
GAL  A 200 (-3.7A)
GAL  A 200 (-3.6A)
BGC  A 201 ( 3.1A)
 0.70A 3galB-1ww6A:
15.5		 3galB-1ww6A:
23.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_K_BO2K1402_1
(PROTEASOME COMPONENT
PRE2
PROTEASOME COMPONENT
C5)		 1ww6 GALECTIN
(Agrocybe
cylindracea) 		5 / 11 ALA A  49
THR A  48
ALA A  64
ALA A  15
GLY A  14
 None
None
GAL  A 200 ( 4.3A)
None
None
 0.87A 3mg0K-1ww6A:
undetectable
3mg0L-1ww6A:
undetectable		 3mg0K-1ww6A:
20.18
3mg0L-1ww6A:
22.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SOA_A_DB8A445_1
(CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE TYPE II
SUBUNIT ALPHA WITH A
BETA 7 LINKER)		 1ww6 GALECTIN
(Agrocybe
cylindracea) 		4 / 6 VAL A 123
PHE A  74
VAL A 107
PHE A  65
 None
 0.92A 3soaA-1ww6A:
undetectable		 3soaA-1ww6A:
17.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V7P_A_BEZA430_0
(AMIDOHYDROLASE
FAMILY PROTEIN)		 1ww6 GALECTIN
(Agrocybe
cylindracea) 		4 / 7 ILE A  97
GLY A  98
SER A  99
LEU A  36
 None
 0.90A 3v7pA-1ww6A:
undetectable		 3v7pA-1ww6A:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KM0_A_CP6A201_1
(DIHYDROFOLATE
REDUCTASE)		 1ww6 GALECTIN
(Agrocybe
cylindracea) 		5 / 10 ALA A  49
PHE A  31
THR A 134
LEU A  19
THR A  48
 None
 1.24A 4km0A-1ww6A:
undetectable		 4km0A-1ww6A:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L1W_A_STRA402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 1ww6 GALECTIN
(Agrocybe
cylindracea) 		4 / 7 VAL A 152
ILE A  11
LEU A  61
LEU A  52
 None
 1.00A 4l1wA-1ww6A:
undetectable		 4l1wA-1ww6A:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XO7_A_ASDA402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 1ww6 GALECTIN
(Agrocybe
cylindracea) 		4 / 7 VAL A 152
ILE A  11
LEU A  61
LEU A  52
 None
 0.96A 4xo7A-1ww6A:
undetectable		 4xo7A-1ww6A:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B8K_A_W9TA300_0
(GALECTIN-3)		 1ww6 GALECTIN
(Agrocybe
cylindracea) 		6 / 7 HIS A  62
ARG A  66
ASN A  75
TRP A  83
GLU A  86
ARG A  88
 GAL  A 200 (-4.1A)
BGC  A 201 ( 3.0A)
GAL  A 200 (-3.7A)
GAL  A 200 (-3.6A)
BGC  A 201 ( 3.1A)
BGC  A 201 ( 4.3A)
 0.57A 6b8kA-1ww6A:
15.8		 6b8kA-1ww6A:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B94_A_W9TA201_0
(GALECTIN-1)		 1ww6 GALECTIN
(Agrocybe
cylindracea) 		5 / 8 HIS A  62
ARG A  66
ASN A  75
TRP A  83
ARG A  88
 GAL  A 200 (-4.1A)
BGC  A 201 ( 3.0A)
GAL  A 200 (-3.7A)
GAL  A 200 (-3.6A)
BGC  A 201 ( 4.3A)
 0.84A 6b94A-1ww6A:
14.6		 6b94A-1ww6A:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B94_A_W9TA201_0
(GALECTIN-1)		 1ww6 GALECTIN
(Agrocybe
cylindracea) 		5 / 8 HIS A  62
ARG A  66
ASN A  75
TRP A  83
GLU A  86
 GAL  A 200 (-4.1A)
BGC  A 201 ( 3.0A)
GAL  A 200 (-3.7A)
GAL  A 200 (-3.6A)
BGC  A 201 ( 3.1A)
 0.73A 6b94A-1ww6A:
14.6		 6b94A-1ww6A:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B94_B_W9TB201_0
(GALECTIN-1)		 1ww6 GALECTIN
(Agrocybe
cylindracea) 		6 / 10 HIS A  62
ARG A  66
ASN A  75
TRP A  83
GLU A  86
ARG A  88
 GAL  A 200 (-4.1A)
BGC  A 201 ( 3.0A)
GAL  A 200 (-3.7A)
GAL  A 200 (-3.6A)
BGC  A 201 ( 3.1A)
BGC  A 201 ( 4.3A)
 0.73A 6b94A-1ww6A:
14.6
6b94B-1ww6A:
14.2		 6b94A-1ww6A:
20.25
6b94B-1ww6A:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN4_F_AM2F301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 1ww6 GALECTIN
(Agrocybe
cylindracea) 		4 / 7 TRP A  83
HIS A  62
ARG A  88
GLU A  69
 GAL  A 200 (-3.6A)
GAL  A 200 (-4.1A)
BGC  A 201 ( 4.3A)
None
 1.42A 6mn4F-1ww6A:
undetectable		 6mn4F-1ww6A:
19.69