SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1wwm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1B2I_A_AMHA84_1
(PROTEIN
(PLASMINOGEN))		 1wwm HYPOTHETICAL PROTEIN
TT2028
(Thermus
thermophilus) 		4 / 7 TYR A 110
ASP A 167
GLU A 169
PHE A 114
 None
 1.47A 1b2iA-1wwmA:
undetectable		 1b2iA-1wwmA:
16.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DFR_A_MTXA164_1
(DIHYDROFOLATE
REDUCTASE)		 1wwm HYPOTHETICAL PROTEIN
TT2028
(Thermus
thermophilus) 		5 / 12 LEU A  22
ALA A 125
LEU A 179
PRO A  13
ALA A  21
 None
 1.00A 3dfrA-1wwmA:
undetectable		 3dfrA-1wwmA:
22.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NS1_L_PM6L1_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 1wwm HYPOTHETICAL PROTEIN
TT2028
(Thermus
thermophilus) 		4 / 8 PHE A 148
LEU A  45
ALA A  67
ALA A  70
 None
 0.93A 3ns1L-1wwmA:
undetectable		 3ns1L-1wwmA:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUE_B_SUEB1201_2
(NS3 PROTEASE, NS4A
PROTEIN)		 1wwm HYPOTHETICAL PROTEIN
TT2028
(Thermus
thermophilus) 		3 / 3 PHE A 115
TYR A  46
LEU A 106
 None
 0.77A 3sueB-1wwmA:
undetectable		 3sueB-1wwmA:
18.96