SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1wwp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_B_DCFB853_2
(ADENOSINE DEAMINASE)		 1wwp HYPOTHETICAL PROTEIN
TTHA0636
(Thermus
thermophilus) 		4 / 5 LEU A  76
SER A  85
LEU A  86
GLY A  79
 None
 1.13A 1a4lB-1wwpA:
undetectable		 1a4lB-1wwpA:
18.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UKB_A_BEZA1301_0
(2-HYDROXY-6-OXO-7-ME
THYLOCTA-2,4-DIENOAT
E HYDROLASE)		 1wwp HYPOTHETICAL PROTEIN
TTHA0636
(Thermus
thermophilus) 		4 / 6 LEU A   6
PHE A  37
ALA A  36
LEU A   9
 None
 0.99A 1ukbA-1wwpA:
undetectable		 1ukbA-1wwpA:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q6H_A_CXXA801_1
(TRANSPORTER)		 1wwp HYPOTHETICAL PROTEIN
TTHA0636
(Thermus
thermophilus) 		5 / 11 LEU A 117
LEU A 114
ARG A 116
GLN A 112
PHE A  37
 None
 1.22A 2q6hA-1wwpA:
undetectable		 2q6hA-1wwpA:
13.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD4_B_CHDB927_0
(FERROCHELATASE)		 1wwp HYPOTHETICAL PROTEIN
TTHA0636
(Thermus
thermophilus) 		3 / 3 LEU A 103
PRO A 104
ARG A  97
 None
 0.65A 2qd4B-1wwpA:
undetectable		 2qd4B-1wwpA:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEI_A_CXXA801_1
(TRANSPORTER)		 1wwp HYPOTHETICAL PROTEIN
TTHA0636
(Thermus
thermophilus) 		5 / 11 LEU A 117
LEU A 114
ARG A 116
GLN A 112
PHE A  37
 None
 1.26A 2qeiA-1wwpA:
undetectable		 2qeiA-1wwpA:
13.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FE1_A_PQNA846_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX)		 1wwp HYPOTHETICAL PROTEIN
TTHA0636
(Thermus
thermophilus) 		5 / 10 ARG A  64
ALA A  74
LEU A  69
GLY A  67
ALA A   5
 None
 1.13A 4fe1A-1wwpA:
undetectable
4fe1J-1wwpA:
undetectable		 4fe1A-1wwpA:
10.53
4fe1J-1wwpA:
17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L6V_1_PQN12001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
FUSION PROTEIN OF
PHOTOSYSTEM I
SUBUNIT III AND
SUBUNIT IX)		 1wwp HYPOTHETICAL PROTEIN
TTHA0636
(Thermus
thermophilus) 		5 / 11 ARG A  64
ALA A  74
LEU A  69
GLY A  67
ALA A   5
 None
 1.19A 4l6v1-1wwpA:
undetectable
4l6v6-1wwpA:
undetectable		 4l6v1-1wwpA:
10.59
4l6v6-1wwpA:
23.45