SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1wwu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1Y7I_A_SALA501_1 (SALICYLIC ACID-BINDING PROTEIN 2)	1wwu	HYPOTHETICAL PROTEIN FLJ21935 (Homo sapiens)	5 / 9	GLY A 70 LEU A 62 TRP A 32 PHE A 38 LEU A 54	None	1.26A	1y7iA-1wwuA: undetectable	1y7iA-1wwuA: 18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BM9_A_SAMA301_0 (CEPHALOSPORIN HYDROXYLASE CMCI)	1wwu	HYPOTHETICAL PROTEIN FLJ21935 (Homo sapiens)	5 / 12	LEU A 54 LEU A 33 GLU A 69 GLY A 70 SER A 39	None	1.05A	2bm9A-1wwuA: undetectable	2bm9A-1wwuA: 18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BM9_D_SAMD301_0 (CEPHALOSPORIN HYDROXYLASE CMCI)	1wwu	HYPOTHETICAL PROTEIN FLJ21935 (Homo sapiens)	5 / 12	LEU A 54 LEU A 33 GLU A 69 GLY A 70 SER A 39	None	1.10A	2bm9D-1wwuA: undetectable	2bm9D-1wwuA: 18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BR4_D_SAMD301_0 (CEPHALOSPORIN HYDROXYLASE CMCI)	1wwu	HYPOTHETICAL PROTEIN FLJ21935 (Homo sapiens)	5 / 12	LEU A 54 LEU A 33 GLU A 69 GLY A 70 SER A 39	None	1.18A	2br4D-1wwuA: undetectable	2br4D-1wwuA: 18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BR4_F_SAMF301_0 (CEPHALOSPORIN HYDROXYLASE CMCI)	1wwu	HYPOTHETICAL PROTEIN FLJ21935 (Homo sapiens)	5 / 12	LEU A 54 LEU A 33 GLU A 69 GLY A 70 SER A 39	None	1.09A	2br4F-1wwuA: undetectable	2br4F-1wwuA: 18.86

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1Y7I_A_SALA501_1","SALICYLIC ACID-BINDING PROTEIN 2","1wwu","HYPOTHETICAL PROTEIN FLJ21935","Homo sapiens",5,"GLY A  70;LEU A  62;TRP A  32;PHE A  38;LEU A  54","None","1.26A","1y7iA-1wwuA:undetectable","1y7iA-1wwuA:18.35"],["2BM9_A_SAMA301_0","CEPHALOSPORIN HYDROXYLASE CMCI","1wwu","HYPOTHETICAL PROTEIN FLJ21935","Homo sapiens",5,"LEU A  54;LEU A  33;GLU A  69;GLY A  70;SER A  39","None","1.05A","2bm9A-1wwuA:undetectable","2bm9A-1wwuA:18.86"],["2BM9_D_SAMD301_0","CEPHALOSPORIN HYDROXYLASE CMCI","1wwu","HYPOTHETICAL PROTEIN FLJ21935","Homo sapiens",5,"LEU A  54;LEU A  33;GLU A  69;GLY A  70;SER A  39","None","1.10A","2bm9D-1wwuA:undetectable","2bm9D-1wwuA:18.86"],["2BR4_D_SAMD301_0","CEPHALOSPORIN HYDROXYLASE CMCI","1wwu","HYPOTHETICAL PROTEIN FLJ21935","Homo sapiens",5,"LEU A  54;LEU A  33;GLU A  69;GLY A  70;SER A  39","None","1.18A","2br4D-1wwuA:undetectable","2br4D-1wwuA:18.86"],["2BR4_F_SAMF301_0","CEPHALOSPORIN HYDROXYLASE CMCI","1wwu","HYPOTHETICAL PROTEIN FLJ21935","Homo sapiens",5,"LEU A  54;LEU A  33;GLU A  69;GLY A  70;SER A  39","None","1.09A","2br4F-1wwuA:undetectable","2br4F-1wwuA:18.86"]]