SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1wwy'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIJ_B_NOVB444_2
(DNA GYRASE SUBUNIT B)		 1wwy THIOREDOXIN-LIKE
PROTEIN 1
(Homo
sapiens) 		3 / 3 ASP A  33
PHE A 149
VAL A  55
 None
 0.68A 1kijB-1wwyA:
undetectable		 1kijB-1wwyA:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BWC_A_SAMA501_0
(SPERMIDINE SYNTHASE)		 1wwy THIOREDOXIN-LIKE
PROTEIN 1
(Homo
sapiens) 		5 / 12 ILE A 146
ILE A 111
ASP A 110
VAL A 117
GLY A  70
 None
 0.94A 3bwcA-1wwyA:
undetectable		 3bwcA-1wwyA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BWC_B_SAMB501_0
(SPERMIDINE SYNTHASE)		 1wwy THIOREDOXIN-LIKE
PROTEIN 1
(Homo
sapiens) 		5 / 12 ILE A 146
ILE A 111
ASP A 110
VAL A 117
GLY A  70
 None
 1.02A 3bwcB-1wwyA:
undetectable		 3bwcB-1wwyA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VT7_A_VDXA500_2
(VITAMIN D3 RECEPTOR)		 1wwy THIOREDOXIN-LIKE
PROTEIN 1
(Homo
sapiens) 		4 / 4 LEU A  12
ILE A 116
TYR A 148
TYR A  64
 None
 1.27A 3vt7A-1wwyA:
undetectable		 3vt7A-1wwyA:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_D_9F2D400_2
(BETA-LACTAMASE)		 1wwy THIOREDOXIN-LIKE
PROTEIN 1
(Homo
sapiens) 		4 / 4 CYH A  35
ILE A 111
PRO A  71
THR A 150
 None
 1.19A 6b68D-1wwyA:
0.0		 6b68D-1wwyA:
16.96