SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1wx4'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JG4_A_SAMA500_1
(PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		4 / 8 GLY A 199
SER A 206
ILE A 129
ASP A 112
 None
PER  A 409 ( 4.1A)
None
None
 0.92A 1jg4A-1wx4A:
undetectable		 1jg4A-1wx4A:
22.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OS2_A_HAEA874_1
(MACROPHAGE
METALLOELASTASE)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		4 / 5 HIS A 215
HIS A  54
HIS A  63
HIS A  38
 None
CU  A 400 ( 3.3A)
CU  A 400 ( 3.5A)
CU  A 400 ( 3.3A)
 1.13A 1os2A-1wx4A:
undetectable		 1os2A-1wx4A:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QWC_A_H4BA901_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		3 / 3 ARG A  92
VAL A 147
TRP A 196
 None
 1.26A 1qwcA-1wx4A:
undetectable		 1qwcA-1wx4A:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RQP_B_SAMB500_1
(5'-FLUORO-5'-DEOXYAD
ENOSINE SYNTHASE)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		4 / 8 ASN A   6
SER A  89
ARG A 153
ALA A   8
 None
 1.15A 1rqpC-1wx4A:
undetectable		 1rqpC-1wx4A:
24.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RQP_C_SAMC500_0
(5'-FLUORO-5'-DEOXYAD
ENOSINE SYNTHASE)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		4 / 8 ASN A   6
SER A  89
ARG A 153
ALA A   8
 None
 1.16A 1rqpA-1wx4A:
undetectable		 1rqpA-1wx4A:
24.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VAG_A_H4BA901_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		3 / 3 ARG A  92
VAL A 147
TRP A 196
 None
 1.27A 1vagA-1wx4A:
0.7		 1vagA-1wx4A:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZVI_A_H4BA901_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		3 / 3 ARG A  92
VAL A 147
TRP A 196
 None
 1.25A 1zviA-1wx4A:
undetectable		 1zviA-1wx4A:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZR_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		4 / 7 VAL A 193
ARG A  92
VAL A 147
TRP A 196
 None
 1.22A 1zzrA-1wx4A:
undetectable
1zzrB-1wx4A:
undetectable		 1zzrA-1wx4A:
21.96
1zzrB-1wx4A:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZR_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		4 / 7 VAL A 193
ARG A  92
VAL A 147
TRP A 196
 None
 1.24A 1zzrA-1wx4A:
undetectable
1zzrB-1wx4A:
undetectable		 1zzrA-1wx4A:
21.96
1zzrB-1wx4A:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZU_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		4 / 7 VAL A 193
ARG A  92
VAL A 147
TRP A 196
 None
 1.19A 1zzuA-1wx4A:
0.6
1zzuB-1wx4A:
0.9		 1zzuA-1wx4A:
21.96
1zzuB-1wx4A:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZU_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		4 / 7 VAL A 193
ARG A  92
VAL A 147
TRP A 196
 None
 1.22A 1zzuA-1wx4A:
0.6
1zzuB-1wx4A:
0.9		 1zzuA-1wx4A:
21.96
1zzuB-1wx4A:
21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JIH_A_097A1001_1
(ADAMTS-1)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		5 / 9 LEU A 189
HIS A 215
HIS A 194
HIS A 216
LEU A 222
 None
None
CU  A 401 ( 3.2A)
CU  A 401 ( 3.4A)
None
 1.28A 2jihA-1wx4A:
undetectable		 2jihA-1wx4A:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V7U_A_SAMA1299_0
(5'-FLUORO-5'-DEOXY
ADENOSINE SYNTHETASE)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		4 / 8 ASN A   6
SER A  89
ARG A 153
ALA A   8
 None
 1.13A 2v7uA-1wx4A:
undetectable		 2v7uA-1wx4A:
24.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WKO_F_CUF154_0
(SUPEROXIDE DISMUTASE
[CU-ZN])		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		4 / 5 HIS A 190
HIS A 194
VAL A 219
HIS A 216
 CU  A 401 ( 3.2A)
CU  A 401 ( 3.2A)
None
CU  A 401 ( 3.4A)
 0.98A 2wkoF-1wx4A:
undetectable		 2wkoF-1wx4A:
18.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ZWE_B_DAHB98_1
(TYROSINASE
MELC)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		8 / 11 HIS A  38
ILE A  42
HIS A  54
HIS A 190
ASN A 191
HIS A 194
VAL A 195
SER A 206
 CU  A 400 ( 3.3A)
None
CU  A 400 ( 3.3A)
CU  A 401 ( 3.2A)
None
CU  A 401 ( 3.2A)
None
PER  A 409 ( 4.1A)
 0.25A 2zweA-1wx4A:
50.0
2zweB-1wx4A:
undetectable		 2zweA-1wx4A:
100.00
2zweB-1wx4A:
20.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ZWE_B_DAHB98_1
(TYROSINASE
MELC)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		5 / 11 HIS A 194
HIS A 190
HIS A  54
HIS A  38
SER A 206
 CU  A 401 ( 3.2A)
CU  A 401 ( 3.2A)
CU  A 400 ( 3.3A)
CU  A 400 ( 3.3A)
PER  A 409 ( 4.1A)
 1.00A 2zweA-1wx4A:
50.0
2zweB-1wx4A:
undetectable		 2zweA-1wx4A:
100.00
2zweB-1wx4A:
20.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ZWE_B_DAHB98_1
(TYROSINASE
MELC)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		5 / 11 HIS A 194
HIS A 190
HIS A  63
HIS A  38
SER A 206
 CU  A 401 ( 3.2A)
CU  A 401 ( 3.2A)
CU  A 400 ( 3.5A)
CU  A 400 ( 3.3A)
PER  A 409 ( 4.1A)
 1.50A 2zweA-1wx4A:
50.0
2zweB-1wx4A:
undetectable		 2zweA-1wx4A:
100.00
2zweB-1wx4A:
20.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ZWE_B_DAHB98_1
(TYROSINASE
MELC)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		5 / 11 HIS A 194
HIS A 216
HIS A  54
HIS A  38
SER A 206
 CU  A 401 ( 3.2A)
CU  A 401 ( 3.4A)
CU  A 400 ( 3.3A)
CU  A 400 ( 3.3A)
PER  A 409 ( 4.1A)
 1.32A 2zweA-1wx4A:
50.0
2zweB-1wx4A:
undetectable		 2zweA-1wx4A:
100.00
2zweB-1wx4A:
20.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ZWE_B_DAHB98_1
(TYROSINASE
MELC)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		5 / 11 ILE A  42
HIS A  54
HIS A 216
HIS A 194
SER A 206
 None
CU  A 400 ( 3.3A)
CU  A 401 ( 3.4A)
CU  A 401 ( 3.2A)
PER  A 409 ( 4.1A)
 1.42A 2zweA-1wx4A:
50.0
2zweB-1wx4A:
undetectable		 2zweA-1wx4A:
100.00
2zweB-1wx4A:
20.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ZWF_B_DAHB98_1
(TYROSINASE
MELC)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		8 / 11 HIS A  38
ILE A  42
HIS A  54
HIS A 190
ASN A 191
HIS A 194
VAL A 195
SER A 206
 CU  A 400 ( 3.3A)
None
CU  A 400 ( 3.3A)
CU  A 401 ( 3.2A)
None
CU  A 401 ( 3.2A)
None
PER  A 409 ( 4.1A)
 0.15A 2zwfA-1wx4A:
50.0
2zwfB-1wx4A:
undetectable		 2zwfA-1wx4A:
100.00
2zwfB-1wx4A:
20.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ZWF_B_DAHB98_1
(TYROSINASE
MELC)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		5 / 11 HIS A 194
HIS A 190
HIS A  54
HIS A  38
SER A 206
 CU  A 401 ( 3.2A)
CU  A 401 ( 3.2A)
CU  A 400 ( 3.3A)
CU  A 400 ( 3.3A)
PER  A 409 ( 4.1A)
 0.95A 2zwfA-1wx4A:
50.0
2zwfB-1wx4A:
undetectable		 2zwfA-1wx4A:
100.00
2zwfB-1wx4A:
20.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ZWF_B_DAHB98_1
(TYROSINASE
MELC)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		5 / 11 HIS A 194
HIS A 190
HIS A  63
HIS A  38
SER A 206
 CU  A 401 ( 3.2A)
CU  A 401 ( 3.2A)
CU  A 400 ( 3.5A)
CU  A 400 ( 3.3A)
PER  A 409 ( 4.1A)
 1.44A 2zwfA-1wx4A:
50.0
2zwfB-1wx4A:
undetectable		 2zwfA-1wx4A:
100.00
2zwfB-1wx4A:
20.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ZWF_B_DAHB98_1
(TYROSINASE
MELC)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		5 / 11 HIS A 194
HIS A 216
HIS A  54
HIS A  38
SER A 206
 CU  A 401 ( 3.2A)
CU  A 401 ( 3.4A)
CU  A 400 ( 3.3A)
CU  A 400 ( 3.3A)
PER  A 409 ( 4.1A)
 1.38A 2zwfA-1wx4A:
50.0
2zwfB-1wx4A:
undetectable		 2zwfA-1wx4A:
100.00
2zwfB-1wx4A:
20.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ZWG_B_DAHB98_1
(TYROSINASE
MELC)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		8 / 11 HIS A  38
ILE A  42
HIS A  54
HIS A 190
ASN A 191
HIS A 194
VAL A 195
SER A 206
 CU  A 400 ( 3.3A)
None
CU  A 400 ( 3.3A)
CU  A 401 ( 3.2A)
None
CU  A 401 ( 3.2A)
None
PER  A 409 ( 4.1A)
 0.17A 2zwgA-1wx4A:
49.9
2zwgB-1wx4A:
undetectable		 2zwgA-1wx4A:
100.00
2zwgB-1wx4A:
20.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ZWG_B_DAHB98_1
(TYROSINASE
MELC)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		5 / 11 HIS A 194
HIS A 190
HIS A  54
HIS A  38
SER A 206
 CU  A 401 ( 3.2A)
CU  A 401 ( 3.2A)
CU  A 400 ( 3.3A)
CU  A 400 ( 3.3A)
PER  A 409 ( 4.1A)
 0.93A 2zwgA-1wx4A:
49.9
2zwgB-1wx4A:
undetectable		 2zwgA-1wx4A:
100.00
2zwgB-1wx4A:
20.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ZWG_B_DAHB98_1
(TYROSINASE
MELC)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		5 / 11 HIS A 194
HIS A 190
HIS A  63
HIS A  38
SER A 206
 CU  A 401 ( 3.2A)
CU  A 401 ( 3.2A)
CU  A 400 ( 3.5A)
CU  A 400 ( 3.3A)
PER  A 409 ( 4.1A)
 1.42A 2zwgA-1wx4A:
49.9
2zwgB-1wx4A:
undetectable		 2zwgA-1wx4A:
100.00
2zwgB-1wx4A:
20.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ZWG_B_DAHB98_1
(TYROSINASE
MELC)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		5 / 11 HIS A 194
HIS A 216
HIS A  54
HIS A  38
SER A 206
 CU  A 401 ( 3.2A)
CU  A 401 ( 3.4A)
CU  A 400 ( 3.3A)
CU  A 400 ( 3.3A)
PER  A 409 ( 4.1A)
 1.38A 2zwgA-1wx4A:
49.9
2zwgB-1wx4A:
undetectable		 2zwgA-1wx4A:
100.00
2zwgB-1wx4A:
20.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ZWG_B_DAHB98_1
(TYROSINASE
MELC)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		5 / 11 ILE A  42
HIS A  54
HIS A 216
HIS A 194
SER A 206
 None
CU  A 400 ( 3.3A)
CU  A 401 ( 3.4A)
CU  A 401 ( 3.2A)
PER  A 409 ( 4.1A)
 1.40A 2zwgA-1wx4A:
49.9
2zwgB-1wx4A:
undetectable		 2zwgA-1wx4A:
100.00
2zwgB-1wx4A:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DQR_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		4 / 7 VAL A 193
ARG A  92
VAL A 147
TRP A 196
 None
 1.20A 3dqrA-1wx4A:
undetectable
3dqrB-1wx4A:
undetectable		 3dqrA-1wx4A:
21.86
3dqrB-1wx4A:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HY7_A_097A801_1
(A DISINTEGRIN AND
METALLOPROTEINASE
WITH THROMBOSPONDIN
MOTIFS 5)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		5 / 9 LEU A 189
HIS A 215
HIS A 194
HIS A 216
LEU A 222
 None
None
CU  A 401 ( 3.2A)
CU  A 401 ( 3.4A)
None
 1.16A 3hy7A-1wx4A:
undetectable		 3hy7A-1wx4A:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HY7_B_097B801_1
(A DISINTEGRIN AND
METALLOPROTEINASE
WITH THROMBOSPONDIN
MOTIFS 5)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		5 / 9 LEU A 189
HIS A 215
HIS A 194
HIS A 216
LEU A 222
 None
None
CU  A 401 ( 3.2A)
CU  A 401 ( 3.4A)
None
 1.21A 3hy7B-1wx4A:
undetectable		 3hy7B-1wx4A:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LIK_A_HAEA302_1
(MACROPHAGE
METALLOELASTASE)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		4 / 5 HIS A 215
HIS A  54
HIS A  63
HIS A  38
 None
CU  A 400 ( 3.3A)
CU  A 400 ( 3.5A)
CU  A 400 ( 3.3A)
 1.12A 3likA-1wx4A:
undetectable		 3likA-1wx4A:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LKA_A_HAEA269_1
(MACROPHAGE
METALLOELASTASE)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		4 / 5 HIS A 215
HIS A  54
HIS A  63
HIS A  38
 None
CU  A 400 ( 3.3A)
CU  A 400 ( 3.5A)
CU  A 400 ( 3.3A)
 1.10A 3lkaA-1wx4A:
undetectable		 3lkaA-1wx4A:
18.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QPK_A_CUA602_0
(LACCASE-1)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		3 / 3 HIS A  54
HIS A  63
HIS A  38
 CU  A 400 ( 3.3A)
CU  A 400 ( 3.5A)
CU  A 400 ( 3.3A)
 0.36A 3qpkA-1wx4A:
undetectable		 3qpkA-1wx4A:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QPK_B_CUB602_0
(LACCASE-1)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		3 / 3 HIS A  54
HIS A  63
HIS A  38
 CU  A 400 ( 3.3A)
CU  A 400 ( 3.5A)
CU  A 400 ( 3.3A)
 0.34A 3qpkB-1wx4A:
undetectable		 3qpkB-1wx4A:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFN_A_ROCA402_1
(HIV-1 PROTEASE)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		4 / 5 ARG A 178
LEU A  60
PRO A 259
ASP A 166
 None
 1.14A 3ufnA-1wx4A:
undetectable
3ufnB-1wx4A:
undetectable		 3ufnA-1wx4A:
16.24
3ufnB-1wx4A:
16.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VQR_A_ACTA1002_0
(PUTATIVE
OXIDOREDUCTASE)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		4 / 6 ASP A 209
GLY A 198
VAL A 197
THR A 203
 None
 1.03A 3vqrA-1wx4A:
undetectable		 3vqrA-1wx4A:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VQR_B_ACTB1002_0
(PUTATIVE
OXIDOREDUCTASE)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		4 / 5 ASP A 209
GLY A 198
VAL A 197
THR A 203
 None
 1.03A 3vqrB-1wx4A:
undetectable		 3vqrB-1wx4A:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX3_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		4 / 7 VAL A 193
ARG A  92
VAL A 147
TRP A 196
 None
 1.23A 4cx3A-1wx4A:
0.6
4cx3B-1wx4A:
undetectable		 4cx3A-1wx4A:
21.86
4cx3B-1wx4A:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX3_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		4 / 7 VAL A 193
ARG A  92
VAL A 147
TRP A 196
 None
 1.25A 4cx3A-1wx4A:
0.6
4cx3B-1wx4A:
undetectable		 4cx3A-1wx4A:
21.86
4cx3B-1wx4A:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX4_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		4 / 7 VAL A 193
ARG A  92
VAL A 147
TRP A 196
 None
 1.21A 4cx4A-1wx4A:
0.6
4cx4B-1wx4A:
undetectable		 4cx4A-1wx4A:
21.86
4cx4B-1wx4A:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX4_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		4 / 7 VAL A 193
ARG A  92
VAL A 147
TRP A 196
 None
 1.23A 4cx4A-1wx4A:
0.6
4cx4B-1wx4A:
undetectable		 4cx4A-1wx4A:
21.86
4cx4B-1wx4A:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N48_A_SAMA601_1
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		4 / 5 ALA A 100
GLY A 105
ASP A  78
ASP A 102
 None
 0.90A 4n48A-1wx4A:
undetectable		 4n48A-1wx4A:
20.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4P6S_A_DAHA305_1
(TYROSINASE)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		5 / 7 HIS A  38
HIS A  54
HIS A 190
ASN A 191
HIS A 194
 CU  A 400 ( 3.3A)
CU  A 400 ( 3.3A)
CU  A 401 ( 3.2A)
None
CU  A 401 ( 3.2A)
 0.43A 4p6sA-1wx4A:
39.3		 4p6sA-1wx4A:
43.84
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4P6S_B_DAHB305_1
(TYROSINASE)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		5 / 7 HIS A  38
HIS A  54
HIS A 190
ASN A 191
HIS A 194
 CU  A 400 ( 3.3A)
CU  A 400 ( 3.3A)
CU  A 401 ( 3.2A)
None
CU  A 401 ( 3.2A)
 0.34A 4p6sB-1wx4A:
39.1		 4p6sB-1wx4A:
43.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		3 / 3 ARG A  92
VAL A 147
TRP A 196
 None
 1.26A 5fvoA-1wx4A:
undetectable		 5fvoA-1wx4A:
22.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5I3A_A_HQEA303_1
(TYROSINASE)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		5 / 7 HIS A  38
HIS A  54
HIS A 190
ASN A 191
HIS A 194
 CU  A 400 ( 3.3A)
CU  A 400 ( 3.3A)
CU  A 401 ( 3.2A)
None
CU  A 401 ( 3.2A)
 0.35A 5i3aA-1wx4A:
39.5		 5i3aA-1wx4A:
43.84
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5I3A_B_HQEB304_1
(TYROSINASE)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		5 / 7 HIS A  38
HIS A  54
HIS A 190
ASN A 191
HIS A 194
 CU  A 400 ( 3.3A)
CU  A 400 ( 3.3A)
CU  A 401 ( 3.2A)
None
CU  A 401 ( 3.2A)
 0.32A 5i3aB-1wx4A:
39.3		 5i3aB-1wx4A:
43.84
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5I3B_A_HQEA303_1
(TYROSINASE)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		5 / 7 HIS A  38
HIS A  54
HIS A 190
ASN A 191
HIS A 194
 CU  A 400 ( 3.3A)
CU  A 400 ( 3.3A)
CU  A 401 ( 3.2A)
None
CU  A 401 ( 3.2A)
 0.40A 5i3bA-1wx4A:
39.4		 5i3bA-1wx4A:
43.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JMN_C_FUAC1101_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		3 / 3 VAL A 156
HIS A 190
VAL A 193
 None
CU  A 401 ( 3.2A)
None
 0.67A 5jmnC-1wx4A:
undetectable		 5jmnC-1wx4A:
13.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8N_A_MMSA514_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		6 / 10 HIS A  38
HIS A  54
HIS A 190
ASN A 191
HIS A 194
SER A 206
 CU  A 400 ( 3.3A)
CU  A 400 ( 3.3A)
CU  A 401 ( 3.2A)
None
CU  A 401 ( 3.2A)
PER  A 409 ( 4.1A)
 0.47A 5m8nA-1wx4A:
29.4		 5m8nA-1wx4A:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8N_A_MMSA514_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		5 / 10 HIS A 194
HIS A 216
HIS A  54
HIS A  38
SER A 206
 CU  A 401 ( 3.2A)
CU  A 401 ( 3.4A)
CU  A 400 ( 3.3A)
CU  A 400 ( 3.3A)
PER  A 409 ( 4.1A)
 1.24A 5m8nA-1wx4A:
29.4		 5m8nA-1wx4A:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8N_B_MMSB515_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		6 / 10 HIS A  38
HIS A  54
HIS A 190
ASN A 191
HIS A 194
SER A 206
 CU  A 400 ( 3.3A)
CU  A 400 ( 3.3A)
CU  A 401 ( 3.2A)
None
CU  A 401 ( 3.2A)
PER  A 409 ( 4.1A)
 0.42A 5m8nB-1wx4A:
29.3		 5m8nB-1wx4A:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8N_B_MMSB515_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		5 / 10 HIS A 194
HIS A 216
HIS A  54
HIS A  38
SER A 206
 CU  A 401 ( 3.2A)
CU  A 401 ( 3.4A)
CU  A 400 ( 3.3A)
CU  A 400 ( 3.3A)
PER  A 409 ( 4.1A)
 1.27A 5m8nB-1wx4A:
29.3		 5m8nB-1wx4A:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8N_C_MMSC516_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		6 / 9 HIS A  38
HIS A  54
HIS A 190
ASN A 191
HIS A 194
SER A 206
 CU  A 400 ( 3.3A)
CU  A 400 ( 3.3A)
CU  A 401 ( 3.2A)
None
CU  A 401 ( 3.2A)
PER  A 409 ( 4.1A)
 0.48A 5m8nC-1wx4A:
29.2		 5m8nC-1wx4A:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8N_C_MMSC516_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		5 / 9 HIS A 194
HIS A 216
HIS A  54
HIS A  38
SER A 206
 CU  A 401 ( 3.2A)
CU  A 401 ( 3.4A)
CU  A 400 ( 3.3A)
CU  A 400 ( 3.3A)
PER  A 409 ( 4.1A)
 1.21A 5m8nC-1wx4A:
29.2		 5m8nC-1wx4A:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8N_D_MMSD515_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		5 / 9 HIS A  54
HIS A 190
ASN A 191
HIS A 194
SER A 206
 CU  A 400 ( 3.3A)
CU  A 401 ( 3.2A)
None
CU  A 401 ( 3.2A)
PER  A 409 ( 4.1A)
 0.42A 5m8nD-1wx4A:
28.9		 5m8nD-1wx4A:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8R_A_MMSA511_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		5 / 7 HIS A  54
HIS A 190
ASN A 191
HIS A 194
SER A 206
 CU  A 400 ( 3.3A)
CU  A 401 ( 3.2A)
None
CU  A 401 ( 3.2A)
PER  A 409 ( 4.1A)
 0.30A 5m8rA-1wx4A:
29.4		 5m8rA-1wx4A:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8R_A_MMSA511_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		4 / 7 HIS A 190
HIS A  54
HIS A  38
SER A 206
 CU  A 401 ( 3.2A)
CU  A 400 ( 3.3A)
CU  A 400 ( 3.3A)
PER  A 409 ( 4.1A)
 1.04A 5m8rA-1wx4A:
29.4		 5m8rA-1wx4A:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8R_B_MMSB514_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		5 / 8 HIS A  54
HIS A 190
ASN A 191
HIS A 194
SER A 206
 CU  A 400 ( 3.3A)
CU  A 401 ( 3.2A)
None
CU  A 401 ( 3.2A)
PER  A 409 ( 4.1A)
 0.35A 5m8rB-1wx4A:
29.4		 5m8rB-1wx4A:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8R_C_MMSC516_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		5 / 8 HIS A  54
HIS A 190
ASN A 191
HIS A 194
SER A 206
 CU  A 400 ( 3.3A)
CU  A 401 ( 3.2A)
None
CU  A 401 ( 3.2A)
PER  A 409 ( 4.1A)
 0.34A 5m8rC-1wx4A:
29.4		 5m8rC-1wx4A:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8R_D_MMSD509_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		5 / 8 HIS A  54
HIS A 190
ASN A 191
HIS A 194
SER A 206
 CU  A 400 ( 3.3A)
CU  A 401 ( 3.2A)
None
CU  A 401 ( 3.2A)
PER  A 409 ( 4.1A)
 0.36A 5m8rD-1wx4A:
29.4		 5m8rD-1wx4A:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MFX_A_ACTA701_0
(GENOME POLYPROTEIN)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		4 / 5 ARG A  64
THR A 266
ALA A 267
ASP A 264
 None
NO3  A 408 ( 4.9A)
None
None
 1.40A 5mfxA-1wx4A:
undetectable		 5mfxA-1wx4A:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIG_A_CUA601_0
(LACCASE 2)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		3 / 3 HIS A  54
HIS A  63
HIS A  38
 CU  A 400 ( 3.3A)
CU  A 400 ( 3.5A)
CU  A 400 ( 3.3A)
 0.29A 5migA-1wx4A:
undetectable		 5migA-1wx4A:
19.96
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5Z0F_B_DAHB98_0
(MELC
TYROSINASE)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		8 / 11 HIS A  38
ILE A  42
HIS A  54
HIS A 190
ASN A 191
HIS A 194
VAL A 195
SER A 206
 CU  A 400 ( 3.3A)
None
CU  A 400 ( 3.3A)
CU  A 401 ( 3.2A)
None
CU  A 401 ( 3.2A)
None
PER  A 409 ( 4.1A)
 0.31A 5z0fA-1wx4A:
49.3
5z0fB-1wx4A:
undetectable		 5z0fA-1wx4A:
100.00
5z0fB-1wx4A:
15.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5Z0F_B_DAHB98_0
(MELC
TYROSINASE)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		5 / 11 HIS A 194
HIS A 190
HIS A  54
HIS A  38
SER A 206
 CU  A 401 ( 3.2A)
CU  A 401 ( 3.2A)
CU  A 400 ( 3.3A)
CU  A 400 ( 3.3A)
PER  A 409 ( 4.1A)
 0.97A 5z0fA-1wx4A:
49.3
5z0fB-1wx4A:
undetectable		 5z0fA-1wx4A:
100.00
5z0fB-1wx4A:
15.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5Z0F_B_DAHB98_0
(MELC
TYROSINASE)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		5 / 11 HIS A 194
HIS A 190
HIS A  63
HIS A  38
SER A 206
 CU  A 401 ( 3.2A)
CU  A 401 ( 3.2A)
CU  A 400 ( 3.5A)
CU  A 400 ( 3.3A)
PER  A 409 ( 4.1A)
 1.46A 5z0fA-1wx4A:
49.3
5z0fB-1wx4A:
undetectable		 5z0fA-1wx4A:
100.00
5z0fB-1wx4A:
15.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5Z0F_B_DAHB98_0
(MELC
TYROSINASE)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		5 / 11 HIS A 194
HIS A 216
HIS A  54
HIS A  38
SER A 206
 CU  A 401 ( 3.2A)
CU  A 401 ( 3.4A)
CU  A 400 ( 3.3A)
CU  A 400 ( 3.3A)
PER  A 409 ( 4.1A)
 1.40A 5z0fA-1wx4A:
49.3
5z0fB-1wx4A:
undetectable		 5z0fA-1wx4A:
100.00
5z0fB-1wx4A:
15.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5Z0F_B_DAHB98_0
(MELC
TYROSINASE)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		5 / 11 ILE A  42
HIS A  54
HIS A 216
HIS A 194
SER A 206
 None
CU  A 400 ( 3.3A)
CU  A 401 ( 3.4A)
CU  A 401 ( 3.2A)
PER  A 409 ( 4.1A)
 1.48A 5z0fA-1wx4A:
49.3
5z0fB-1wx4A:
undetectable		 5z0fA-1wx4A:
100.00
5z0fB-1wx4A:
15.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5Z0G_B_DAHB98_0
(MELC
TYROSINASE)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		8 / 11 HIS A  38
ILE A  42
HIS A  54
HIS A 190
ASN A 191
HIS A 194
VAL A 195
SER A 206
 CU  A 400 ( 3.3A)
None
CU  A 400 ( 3.3A)
CU  A 401 ( 3.2A)
None
CU  A 401 ( 3.2A)
None
PER  A 409 ( 4.1A)
 0.33A 5z0gA-1wx4A:
49.8
5z0gB-1wx4A:
undetectable		 5z0gA-1wx4A:
100.00
5z0gB-1wx4A:
15.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5Z0G_B_DAHB98_0
(MELC
TYROSINASE)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		5 / 11 HIS A 194
HIS A 190
HIS A  54
HIS A  38
SER A 206
 CU  A 401 ( 3.2A)
CU  A 401 ( 3.2A)
CU  A 400 ( 3.3A)
CU  A 400 ( 3.3A)
PER  A 409 ( 4.1A)
 0.99A 5z0gA-1wx4A:
49.8
5z0gB-1wx4A:
undetectable		 5z0gA-1wx4A:
100.00
5z0gB-1wx4A:
15.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5Z0G_B_DAHB98_0
(MELC
TYROSINASE)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		5 / 11 HIS A 194
HIS A 190
HIS A  63
HIS A  38
SER A 206
 CU  A 401 ( 3.2A)
CU  A 401 ( 3.2A)
CU  A 400 ( 3.5A)
CU  A 400 ( 3.3A)
PER  A 409 ( 4.1A)
 1.47A 5z0gA-1wx4A:
49.8
5z0gB-1wx4A:
undetectable		 5z0gA-1wx4A:
100.00
5z0gB-1wx4A:
15.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5Z0G_B_DAHB98_0
(MELC
TYROSINASE)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		5 / 11 HIS A 194
HIS A 216
HIS A  54
HIS A  38
SER A 206
 CU  A 401 ( 3.2A)
CU  A 401 ( 3.4A)
CU  A 400 ( 3.3A)
CU  A 400 ( 3.3A)
PER  A 409 ( 4.1A)
 1.39A 5z0gA-1wx4A:
49.8
5z0gB-1wx4A:
undetectable		 5z0gA-1wx4A:
100.00
5z0gB-1wx4A:
15.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5Z0H_B_DAHB98_0
(MELC
TYROSINASE)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		8 / 11 HIS A  38
ILE A  42
HIS A  54
HIS A 190
ASN A 191
HIS A 194
VAL A 195
SER A 206
 CU  A 400 ( 3.3A)
None
CU  A 400 ( 3.3A)
CU  A 401 ( 3.2A)
None
CU  A 401 ( 3.2A)
None
PER  A 409 ( 4.1A)
 0.16A 5z0hA-1wx4A:
49.8
5z0hB-1wx4A:
undetectable		 5z0hA-1wx4A:
100.00
5z0hB-1wx4A:
15.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5Z0H_B_DAHB98_0
(MELC
TYROSINASE)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		5 / 11 HIS A 194
HIS A 190
HIS A  54
HIS A  38
SER A 206
 CU  A 401 ( 3.2A)
CU  A 401 ( 3.2A)
CU  A 400 ( 3.3A)
CU  A 400 ( 3.3A)
PER  A 409 ( 4.1A)
 0.96A 5z0hA-1wx4A:
49.8
5z0hB-1wx4A:
undetectable		 5z0hA-1wx4A:
100.00
5z0hB-1wx4A:
15.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5Z0H_B_DAHB98_0
(MELC
TYROSINASE)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		5 / 11 HIS A 194
HIS A 190
HIS A  63
HIS A  38
SER A 206
 CU  A 401 ( 3.2A)
CU  A 401 ( 3.2A)
CU  A 400 ( 3.5A)
CU  A 400 ( 3.3A)
PER  A 409 ( 4.1A)
 1.41A 5z0hA-1wx4A:
49.8
5z0hB-1wx4A:
undetectable		 5z0hA-1wx4A:
100.00
5z0hB-1wx4A:
15.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5Z0H_B_DAHB98_0
(MELC
TYROSINASE)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		5 / 11 HIS A 194
HIS A 216
HIS A  54
HIS A  38
SER A 206
 CU  A 401 ( 3.2A)
CU  A 401 ( 3.4A)
CU  A 400 ( 3.3A)
CU  A 400 ( 3.3A)
PER  A 409 ( 4.1A)
 1.40A 5z0hA-1wx4A:
49.8
5z0hB-1wx4A:
undetectable		 5z0hA-1wx4A:
100.00
5z0hB-1wx4A:
15.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5Z0I_B_DAHB98_0
(MELC
TYROSINASE)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		8 / 11 HIS A  38
ILE A  42
HIS A  54
HIS A 190
ASN A 191
HIS A 194
VAL A 195
SER A 206
 CU  A 400 ( 3.3A)
None
CU  A 400 ( 3.3A)
CU  A 401 ( 3.2A)
None
CU  A 401 ( 3.2A)
None
PER  A 409 ( 4.1A)
 0.30A 5z0iA-1wx4A:
49.9
5z0iB-1wx4A:
undetectable		 5z0iA-1wx4A:
100.00
5z0iB-1wx4A:
15.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5Z0I_B_DAHB98_0
(MELC
TYROSINASE)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		5 / 11 HIS A 194
HIS A 190
HIS A  54
HIS A  38
SER A 206
 CU  A 401 ( 3.2A)
CU  A 401 ( 3.2A)
CU  A 400 ( 3.3A)
CU  A 400 ( 3.3A)
PER  A 409 ( 4.1A)
 0.96A 5z0iA-1wx4A:
49.9
5z0iB-1wx4A:
undetectable		 5z0iA-1wx4A:
100.00
5z0iB-1wx4A:
15.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5Z0I_B_DAHB98_0
(MELC
TYROSINASE)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		5 / 11 HIS A 194
HIS A 190
HIS A  63
HIS A  38
SER A 206
 CU  A 401 ( 3.2A)
CU  A 401 ( 3.2A)
CU  A 400 ( 3.5A)
CU  A 400 ( 3.3A)
PER  A 409 ( 4.1A)
 1.45A 5z0iA-1wx4A:
49.9
5z0iB-1wx4A:
undetectable		 5z0iA-1wx4A:
100.00
5z0iB-1wx4A:
15.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5Z0I_B_DAHB98_0
(MELC
TYROSINASE)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		5 / 11 HIS A 194
HIS A 216
HIS A  54
HIS A  38
SER A 206
 CU  A 401 ( 3.2A)
CU  A 401 ( 3.4A)
CU  A 400 ( 3.3A)
CU  A 400 ( 3.3A)
PER  A 409 ( 4.1A)
 1.39A 5z0iA-1wx4A:
49.9
5z0iB-1wx4A:
undetectable		 5z0iA-1wx4A:
100.00
5z0iB-1wx4A:
15.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5Z0I_B_DAHB98_0
(MELC
TYROSINASE)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		5 / 11 ILE A  42
HIS A  54
HIS A 216
HIS A 194
SER A 206
 None
CU  A 400 ( 3.3A)
CU  A 401 ( 3.4A)
CU  A 401 ( 3.2A)
PER  A 409 ( 4.1A)
 1.47A 5z0iA-1wx4A:
49.9
5z0iB-1wx4A:
undetectable		 5z0iA-1wx4A:
100.00
5z0iB-1wx4A:
15.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5Z0J_B_DAHB98_0
(MELC
TYROSINASE)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		8 / 11 HIS A  38
ILE A  42
HIS A  54
HIS A 190
ASN A 191
HIS A 194
VAL A 195
SER A 206
 CU  A 400 ( 3.3A)
None
CU  A 400 ( 3.3A)
CU  A 401 ( 3.2A)
None
CU  A 401 ( 3.2A)
None
PER  A 409 ( 4.1A)
 0.15A 5z0jA-1wx4A:
49.6
5z0jB-1wx4A:
undetectable		 5z0jA-1wx4A:
100.00
5z0jB-1wx4A:
15.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5Z0J_B_DAHB98_0
(MELC
TYROSINASE)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		5 / 11 HIS A 194
HIS A 190
HIS A  54
HIS A  38
SER A 206
 CU  A 401 ( 3.2A)
CU  A 401 ( 3.2A)
CU  A 400 ( 3.3A)
CU  A 400 ( 3.3A)
PER  A 409 ( 4.1A)
 0.97A 5z0jA-1wx4A:
49.6
5z0jB-1wx4A:
undetectable		 5z0jA-1wx4A:
100.00
5z0jB-1wx4A:
15.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5Z0J_B_DAHB98_0
(MELC
TYROSINASE)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		5 / 11 HIS A 194
HIS A 190
HIS A  63
HIS A  38
SER A 206
 CU  A 401 ( 3.2A)
CU  A 401 ( 3.2A)
CU  A 400 ( 3.5A)
CU  A 400 ( 3.3A)
PER  A 409 ( 4.1A)
 1.46A 5z0jA-1wx4A:
49.6
5z0jB-1wx4A:
undetectable		 5z0jA-1wx4A:
100.00
5z0jB-1wx4A:
15.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5Z0J_B_DAHB98_0
(MELC
TYROSINASE)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		5 / 11 HIS A 194
HIS A 216
HIS A  54
HIS A  38
SER A 206
 CU  A 401 ( 3.2A)
CU  A 401 ( 3.4A)
CU  A 400 ( 3.3A)
CU  A 400 ( 3.3A)
PER  A 409 ( 4.1A)
 1.36A 5z0jA-1wx4A:
49.6
5z0jB-1wx4A:
undetectable		 5z0jA-1wx4A:
100.00
5z0jB-1wx4A:
15.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5Z0K_B_DAHB98_0
(MELC
TYROSINASE)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		8 / 11 HIS A  38
ILE A  42
HIS A  54
HIS A 190
ASN A 191
HIS A 194
VAL A 195
SER A 206
 CU  A 400 ( 3.3A)
None
CU  A 400 ( 3.3A)
CU  A 401 ( 3.2A)
None
CU  A 401 ( 3.2A)
None
PER  A 409 ( 4.1A)
 0.18A 5z0kA-1wx4A:
49.8
5z0kB-1wx4A:
undetectable		 5z0kA-1wx4A:
100.00
5z0kB-1wx4A:
15.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5Z0K_B_DAHB98_0
(MELC
TYROSINASE)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		5 / 11 HIS A 194
HIS A 190
HIS A  54
HIS A  38
SER A 206
 CU  A 401 ( 3.2A)
CU  A 401 ( 3.2A)
CU  A 400 ( 3.3A)
CU  A 400 ( 3.3A)
PER  A 409 ( 4.1A)
 0.99A 5z0kA-1wx4A:
49.8
5z0kB-1wx4A:
undetectable		 5z0kA-1wx4A:
100.00
5z0kB-1wx4A:
15.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5Z0K_B_DAHB98_0
(MELC
TYROSINASE)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		5 / 11 HIS A 194
HIS A 190
HIS A  63
HIS A  38
SER A 206
 CU  A 401 ( 3.2A)
CU  A 401 ( 3.2A)
CU  A 400 ( 3.5A)
CU  A 400 ( 3.3A)
PER  A 409 ( 4.1A)
 1.45A 5z0kA-1wx4A:
49.8
5z0kB-1wx4A:
undetectable		 5z0kA-1wx4A:
100.00
5z0kB-1wx4A:
15.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5Z0K_B_DAHB98_0
(MELC
TYROSINASE)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		5 / 11 HIS A 194
HIS A 216
HIS A  54
HIS A  38
SER A 206
 CU  A 401 ( 3.2A)
CU  A 401 ( 3.4A)
CU  A 400 ( 3.3A)
CU  A 400 ( 3.3A)
PER  A 409 ( 4.1A)
 1.35A 5z0kA-1wx4A:
49.8
5z0kB-1wx4A:
undetectable		 5z0kA-1wx4A:
100.00
5z0kB-1wx4A:
15.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5Z0L_B_DAHB98_0
(MELC
TYROSINASE)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		8 / 11 HIS A  38
ILE A  42
HIS A  54
HIS A 190
ASN A 191
HIS A 194
VAL A 195
SER A 206
 CU  A 400 ( 3.3A)
None
CU  A 400 ( 3.3A)
CU  A 401 ( 3.2A)
None
CU  A 401 ( 3.2A)
None
PER  A 409 ( 4.1A)
 0.18A 5z0lA-1wx4A:
49.8
5z0lB-1wx4A:
undetectable		 5z0lA-1wx4A:
100.00
5z0lB-1wx4A:
15.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5Z0L_B_DAHB98_0
(MELC
TYROSINASE)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		5 / 11 HIS A 194
HIS A 190
HIS A  54
HIS A  38
SER A 206
 CU  A 401 ( 3.2A)
CU  A 401 ( 3.2A)
CU  A 400 ( 3.3A)
CU  A 400 ( 3.3A)
PER  A 409 ( 4.1A)
 0.97A 5z0lA-1wx4A:
49.8
5z0lB-1wx4A:
undetectable		 5z0lA-1wx4A:
100.00
5z0lB-1wx4A:
15.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5Z0L_B_DAHB98_0
(MELC
TYROSINASE)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		5 / 11 HIS A 194
HIS A 190
HIS A  63
HIS A  38
SER A 206
 CU  A 401 ( 3.2A)
CU  A 401 ( 3.2A)
CU  A 400 ( 3.5A)
CU  A 400 ( 3.3A)
PER  A 409 ( 4.1A)
 1.41A 5z0lA-1wx4A:
49.8
5z0lB-1wx4A:
undetectable		 5z0lA-1wx4A:
100.00
5z0lB-1wx4A:
15.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5Z0L_B_DAHB98_0
(MELC
TYROSINASE)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		5 / 11 HIS A 194
HIS A 216
HIS A  54
HIS A  38
SER A 206
 CU  A 401 ( 3.2A)
CU  A 401 ( 3.4A)
CU  A 400 ( 3.3A)
CU  A 400 ( 3.3A)
PER  A 409 ( 4.1A)
 1.40A 5z0lA-1wx4A:
49.8
5z0lB-1wx4A:
undetectable		 5z0lA-1wx4A:
100.00
5z0lB-1wx4A:
15.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5Z0M_B_DAHB98_0
(MELC
TYROSINASE)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		6 / 11 HIS A  38
HIS A  63
HIS A 190
HIS A 194
VAL A 195
SER A 206
 CU  A 400 ( 3.3A)
CU  A 400 ( 3.5A)
CU  A 401 ( 3.2A)
CU  A 401 ( 3.2A)
None
PER  A 409 ( 4.1A)
 1.49A 5z0mA-1wx4A:
49.7
5z0mB-1wx4A:
undetectable		 5z0mA-1wx4A:
98.75
5z0mB-1wx4A:
15.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5Z0M_B_DAHB98_0
(MELC
TYROSINASE)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		8 / 11 HIS A  38
ILE A  42
HIS A  54
HIS A 190
ASN A 191
HIS A 194
VAL A 195
SER A 206
 CU  A 400 ( 3.3A)
None
CU  A 400 ( 3.3A)
CU  A 401 ( 3.2A)
None
CU  A 401 ( 3.2A)
None
PER  A 409 ( 4.1A)
 0.25A 5z0mA-1wx4A:
49.7
5z0mB-1wx4A:
undetectable		 5z0mA-1wx4A:
98.75
5z0mB-1wx4A:
15.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5Z0M_B_DAHB98_0
(MELC
TYROSINASE)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		5 / 11 HIS A 194
HIS A 190
HIS A  54
HIS A  38
SER A 206
 CU  A 401 ( 3.2A)
CU  A 401 ( 3.2A)
CU  A 400 ( 3.3A)
CU  A 400 ( 3.3A)
PER  A 409 ( 4.1A)
 0.93A 5z0mA-1wx4A:
49.7
5z0mB-1wx4A:
undetectable		 5z0mA-1wx4A:
98.75
5z0mB-1wx4A:
15.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5Z0M_B_DAHB98_0
(MELC
TYROSINASE)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		5 / 11 HIS A 194
HIS A 190
HIS A  63
HIS A  38
SER A 206
 CU  A 401 ( 3.2A)
CU  A 401 ( 3.2A)
CU  A 400 ( 3.5A)
CU  A 400 ( 3.3A)
PER  A 409 ( 4.1A)
 1.36A 5z0mA-1wx4A:
49.7
5z0mB-1wx4A:
undetectable		 5z0mA-1wx4A:
98.75
5z0mB-1wx4A:
15.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5Z0M_B_DAHB98_0
(MELC
TYROSINASE)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		5 / 11 HIS A 194
HIS A 216
HIS A  54
HIS A  38
SER A 206
 CU  A 401 ( 3.2A)
CU  A 401 ( 3.4A)
CU  A 400 ( 3.3A)
CU  A 400 ( 3.3A)
PER  A 409 ( 4.1A)
 1.48A 5z0mA-1wx4A:
49.7
5z0mB-1wx4A:
undetectable		 5z0mA-1wx4A:
98.75
5z0mB-1wx4A:
15.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_A_CUA607_0
(TYROSINASE)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		3 / 3 HIS A 190
HIS A 194
HIS A 216
 CU  A 401 ( 3.2A)
CU  A 401 ( 3.2A)
CU  A 401 ( 3.4A)
 0.09A 5zrdA-1wx4A:
3.1		 5zrdA-1wx4A:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_B_CUB606_0
(TYROSINASE)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		5 / 5 HIS A 190
HIS A 194
PHE A 212
HIS A 215
HIS A 216
 CU  A 401 ( 3.2A)
CU  A 401 ( 3.2A)
PER  A 409 (-4.9A)
None
CU  A 401 ( 3.4A)
 0.33A 5zrdB-1wx4A:
3.7		 5zrdB-1wx4A:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_B_CUB607_0
(TYROSINASE)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		4 / 5 HIS A  38
HIS A  54
HIS A  63
PHE A 212
 CU  A 400 ( 3.3A)
CU  A 400 ( 3.3A)
CU  A 400 ( 3.5A)
PER  A 409 (-4.9A)
 0.36A 5zrdB-1wx4A:
3.7		 5zrdB-1wx4A:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_B_CUB607_0
(TYROSINASE)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		4 / 5 HIS A 190
HIS A 194
HIS A 216
PHE A  59
 CU  A 401 ( 3.2A)
CU  A 401 ( 3.2A)
CU  A 401 ( 3.4A)
None
 1.00A 5zrdB-1wx4A:
3.7		 5zrdB-1wx4A:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_C_CUC604_0
(TYROSINASE)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		4 / 4 HIS A 190
HIS A 194
HIS A 215
HIS A 216
 CU  A 401 ( 3.2A)
CU  A 401 ( 3.2A)
None
CU  A 401 ( 3.4A)
 0.19A 5zrdC-1wx4A:
3.3		 5zrdC-1wx4A:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_C_CUC605_0
(TYROSINASE)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		4 / 5 HIS A  38
HIS A  54
HIS A  63
PHE A 212
 CU  A 400 ( 3.3A)
CU  A 400 ( 3.3A)
CU  A 400 ( 3.5A)
PER  A 409 (-4.9A)
 0.30A 5zrdC-1wx4A:
3.3		 5zrdC-1wx4A:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_C_CUC605_0
(TYROSINASE)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		4 / 5 HIS A 190
HIS A 194
HIS A 216
PHE A  59
 CU  A 401 ( 3.2A)
CU  A 401 ( 3.2A)
CU  A 401 ( 3.4A)
None
 1.04A 5zrdC-1wx4A:
3.3		 5zrdC-1wx4A:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_D_CUD606_0
(TYROSINASE)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		4 / 5 HIS A  38
HIS A  54
HIS A  63
PHE A 212
 CU  A 400 ( 3.3A)
CU  A 400 ( 3.3A)
CU  A 400 ( 3.5A)
PER  A 409 (-4.9A)
 0.40A 5zrdD-1wx4A:
4.6		 5zrdD-1wx4A:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_D_CUD606_0
(TYROSINASE)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		4 / 5 HIS A 190
HIS A 194
HIS A 216
PHE A  59
 CU  A 401 ( 3.2A)
CU  A 401 ( 3.2A)
CU  A 401 ( 3.4A)
None
 1.01A 5zrdD-1wx4A:
4.6		 5zrdD-1wx4A:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZRD_D_CUD607_0
(TYROSINASE)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		4 / 4 HIS A 190
HIS A 194
HIS A 215
HIS A 216
 CU  A 401 ( 3.2A)
CU  A 401 ( 3.2A)
None
CU  A 401 ( 3.4A)
 0.22A 5zrdD-1wx4A:
4.6		 5zrdD-1wx4A:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7U_A_FVTA501_0
(PEPTIDE ABC
TRANSPORTER PERMEASE)		 1wx4 TYROSINASE
(Streptomyces
castaneoglobispo
rus) 		4 / 6 VAL A 205
ASN A 208
ASN A 130
ILE A 129
 None
 1.16A 6h7uA-1wx4A:
undetectable		 6h7uA-1wx4A:
19.22