SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1wy6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_D_BEZD507_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 1wy6 HYPOTHETICAL PROTEIN
ST1625
(Sulfurisphaera
tokodaii) 		4 / 7 PHE A  46
ALA A  15
ILE A  54
ILE A  24
 None
 0.98A 1oniD-1wy6A:
undetectable
1oniF-1wy6A:
undetectable		 1oniD-1wy6A:
22.41
1oniF-1wy6A:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A6D_A_SAMA1350_0
(HYDROXYINDOLE
O-METHYLTRANSFERASE)		 1wy6 HYPOTHETICAL PROTEIN
ST1625
(Sulfurisphaera
tokodaii) 		5 / 12 PHE A  46
LEU A  20
GLY A  27
ILE A  66
VAL A  62
 None
 0.87A 4a6dA-1wy6A:
undetectable		 4a6dA-1wy6A:
18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A6E_A_SAMA1349_0
(HYDROXYINDOLE
O-METHYLTRANSFERASE)		 1wy6 HYPOTHETICAL PROTEIN
ST1625
(Sulfurisphaera
tokodaii) 		5 / 12 PHE A  46
LEU A  20
GLY A  27
ILE A  66
VAL A  62
 None
 0.93A 4a6eA-1wy6A:
undetectable		 4a6eA-1wy6A:
18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CR1_A_T44A201_1
(TRANSTHYRETIN)		 1wy6 HYPOTHETICAL PROTEIN
ST1625
(Sulfurisphaera
tokodaii) 		4 / 5 LEU A 148
ALA A 131
LEU A 129
VAL A  95
 None
 1.08A 5cr1A-1wy6A:
undetectable		 5cr1A-1wy6A:
18.56