SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1wy9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RMT_C_ADNC1503_1
(CLASS B ACID
PHOSPHATASE)		 1wy9 ALLOGRAFT
INFLAMMATORY FACTOR
1
(Mus
musculus) 		4 / 8 PHE A  50
TYR A 103
LEU A 107
GLY A 112
 None
 1.02A 1rmtC-1wy9A:
undetectable		 1rmtC-1wy9A:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRL_D_TFPD207_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 1wy9 ALLOGRAFT
INFLAMMATORY FACTOR
1
(Mus
musculus) 		4 / 8 PHE A  50
PHE A  57
PHE A 106
MET A 110
 None
 0.91A 1wrlC-1wy9A:
7.3
1wrlD-1wy9A:
7.1		 1wrlC-1wy9A:
25.34
1wrlD-1wy9A:
25.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRL_E_TFPE212_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 1wy9 ALLOGRAFT
INFLAMMATORY FACTOR
1
(Mus
musculus) 		4 / 7 PHE A  50
PHE A  57
PHE A 106
MET A 110
 None
 0.92A 1wrlE-1wy9A:
7.3		 1wrlE-1wy9A:
25.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRL_F_TFPF211_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 1wy9 ALLOGRAFT
INFLAMMATORY FACTOR
1
(Mus
musculus) 		4 / 7 PHE A  50
PHE A  57
PHE A 106
MET A 110
 None
 0.93A 1wrlE-1wy9A:
7.3
1wrlF-1wy9A:
7.4		 1wrlE-1wy9A:
25.34
1wrlF-1wy9A:
25.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_C_CHDC102_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 1wy9 ALLOGRAFT
INFLAMMATORY FACTOR
1
(Mus
musculus) 		4 / 7 LEU A  47
LEU A 107
ARG A 108
LEU A 111
 None
 0.63A 4wg0B-1wy9A:
undetectable
4wg0C-1wy9A:
undetectable		 4wg0B-1wy9A:
6.09
4wg0C-1wy9A:
6.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_D_CHDD102_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 1wy9 ALLOGRAFT
INFLAMMATORY FACTOR
1
(Mus
musculus) 		5 / 11 LEU A 107
ARG A 108
LEU A 111
LEU A  43
TYR A  37
 None
 1.04A 4wg0D-1wy9A:
undetectable
4wg0E-1wy9A:
undetectable
4wg0F-1wy9A:
undetectable		 4wg0D-1wy9A:
6.09
4wg0E-1wy9A:
6.09
4wg0F-1wy9A:
6.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_F_CHDF103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 1wy9 ALLOGRAFT
INFLAMMATORY FACTOR
1
(Mus
musculus) 		5 / 11 LEU A 107
ARG A 108
LEU A 111
LEU A  43
TYR A  37
 None
 1.07A 4wg0F-1wy9A:
undetectable
4wg0G-1wy9A:
undetectable
4wg0H-1wy9A:
undetectable		 4wg0F-1wy9A:
6.09
4wg0G-1wy9A:
6.09
4wg0H-1wy9A:
6.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_H_CHDH103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 1wy9 ALLOGRAFT
INFLAMMATORY FACTOR
1
(Mus
musculus) 		5 / 11 LEU A 107
ARG A 108
LEU A 111
GLU A  25
LEU A  47
 None
 1.18A 4wg0H-1wy9A:
undetectable
4wg0I-1wy9A:
undetectable
4wg0J-1wy9A:
undetectable		 4wg0H-1wy9A:
6.09
4wg0I-1wy9A:
6.09
4wg0J-1wy9A:
6.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_H_CHDH103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 1wy9 ALLOGRAFT
INFLAMMATORY FACTOR
1
(Mus
musculus) 		5 / 11 LEU A 107
ARG A 108
LEU A 111
GLU A  25
TYR A  37
 None
 0.97A 4wg0H-1wy9A:
undetectable
4wg0I-1wy9A:
undetectable
4wg0J-1wy9A:
undetectable		 4wg0H-1wy9A:
6.09
4wg0I-1wy9A:
6.09
4wg0J-1wy9A:
6.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_H_CHDH103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 1wy9 ALLOGRAFT
INFLAMMATORY FACTOR
1
(Mus
musculus) 		5 / 11 LEU A 107
ARG A 108
LEU A 111
LEU A  43
TYR A  37
 None
 1.09A 4wg0H-1wy9A:
undetectable
4wg0I-1wy9A:
undetectable
4wg0J-1wy9A:
undetectable		 4wg0H-1wy9A:
6.09
4wg0I-1wy9A:
6.09
4wg0J-1wy9A:
6.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_I_CHDI103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 1wy9 ALLOGRAFT
INFLAMMATORY FACTOR
1
(Mus
musculus) 		5 / 11 LEU A  43
TYR A  37
LEU A 107
ARG A 108
LEU A 111
 None
 1.06A 4wg0G-1wy9A:
undetectable
4wg0H-1wy9A:
undetectable
4wg0I-1wy9A:
undetectable		 4wg0G-1wy9A:
6.09
4wg0H-1wy9A:
6.09
4wg0I-1wy9A:
6.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_J_CHDJ103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 1wy9 ALLOGRAFT
INFLAMMATORY FACTOR
1
(Mus
musculus) 		5 / 11 LEU A 107
ARG A 108
LEU A 111
LEU A  43
TYR A  37
 None
 1.02A 4wg0J-1wy9A:
undetectable
4wg0K-1wy9A:
undetectable
4wg0L-1wy9A:
undetectable		 4wg0J-1wy9A:
6.09
4wg0K-1wy9A:
6.09
4wg0L-1wy9A:
6.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_K_CHDK103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 1wy9 ALLOGRAFT
INFLAMMATORY FACTOR
1
(Mus
musculus) 		5 / 11 LEU A  43
TYR A  37
LEU A 107
ARG A 108
LEU A 111
 None
 0.90A 4wg0I-1wy9A:
undetectable
4wg0J-1wy9A:
undetectable
4wg0K-1wy9A:
undetectable		 4wg0I-1wy9A:
6.09
4wg0J-1wy9A:
6.09
4wg0K-1wy9A:
6.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_L_CHDL103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 1wy9 ALLOGRAFT
INFLAMMATORY FACTOR
1
(Mus
musculus) 		4 / 7 LEU A 107
ARG A 108
LEU A 111
LEU A  47
 None
 0.82A 4wg0L-1wy9A:
undetectable
4wg0M-1wy9A:
undetectable		 4wg0L-1wy9A:
6.09
4wg0M-1wy9A:
6.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_M_CHDM103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 1wy9 ALLOGRAFT
INFLAMMATORY FACTOR
1
(Mus
musculus) 		5 / 11 LEU A  43
TYR A  37
LEU A 107
ARG A 108
LEU A 111
 None
 1.05A 4wg0K-1wy9A:
undetectable
4wg0L-1wy9A:
undetectable
4wg0M-1wy9A:
undetectable		 4wg0K-1wy9A:
6.09
4wg0L-1wy9A:
6.09
4wg0M-1wy9A:
6.09