SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1wye'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ODI_E_ADNE1237_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 1wye 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Sulfurisphaera
tokodaii) 		5 / 11 ARG A 108
GLY A   8
GLU A   9
SER A 134
ILE A  53
 None
 1.46A 1odiE-1wyeA:
undetectable		 1odiE-1wyeA:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V8B_A_ADNA502_2
(ADENOSYLHOMOCYSTEINA
SE)		 1wye 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Sulfurisphaera
tokodaii) 		3 / 3 GLU A 249
GLU A  13
LEU A  22
 None
 0.55A 1v8bA-1wyeA:
4.6		 1v8bA-1wyeA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V8B_B_ADNB1502_2
(ADENOSYLHOMOCYSTEINA
SE)		 1wye 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Sulfurisphaera
tokodaii) 		3 / 3 GLU A 249
GLU A  13
LEU A  22
 None
 0.54A 1v8bB-1wyeA:
4.9		 1v8bB-1wyeA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VQ1_B_SAMB301_0
(N5-GLUTAMINE
METHYLTRANSFERASE,
HEMK)		 1wye 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Sulfurisphaera
tokodaii) 		5 / 12 ILE A  89
GLY A  88
GLY A 113
ILE A  10
ALA A  85
 None
 1.03A 1vq1B-1wyeA:
2.7		 1vq1B-1wyeA:
23.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BM9_A_SAMA301_1
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 1wye 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Sulfurisphaera
tokodaii) 		3 / 3 LYS A  30
ASP A  59
ASN A  64
 None
 0.66A 2bm9A-1wyeA:
undetectable		 2bm9A-1wyeA:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C6N_B_LPRB705_2
(ANGIOTENSIN-CONVERTI
NG ENZYME, SOMATIC
ISOFORM)		 1wye 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Sulfurisphaera
tokodaii) 		3 / 3 ALA A 282
THR A 261
PHE A 305
 None
 0.66A 2c6nB-1wyeA:
undetectable		 2c6nB-1wyeA:
18.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EQM_A_ASDA601_1
(CYTOCHROME P450 19A1)		 1wye 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Sulfurisphaera
tokodaii) 		5 / 10 ILE A 179
ILE A 165
ASP A 197
THR A 193
LEU A 202
 None
 1.22A 3eqmA-1wyeA:
0.0		 3eqmA-1wyeA:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HZN_G_ACTG225_0
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 1wye 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Sulfurisphaera
tokodaii) 		3 / 3 PRO A  21
LEU A  22
GLN A  93
 None
 0.69A 3hznG-1wyeA:
undetectable
3hznH-1wyeA:
undetectable		 3hznG-1wyeA:
21.14
3hznH-1wyeA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K13_A_THHA642_1
(5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE)		 1wye 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Sulfurisphaera
tokodaii) 		3 / 3 ASN A 286
ASP A 250
ARG A 108
 None
 0.93A 3k13A-1wyeA:
2.6		 3k13A-1wyeA:
24.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RET_A_SALA201_1
(SALICYLATE
BIOSYNTHESIS PROTEIN
PCHB)		 1wye 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Sulfurisphaera
tokodaii) 		5 / 10 VAL A  32
VAL A  76
MET A  79
GLN A 293
ILE A  10
 None
 1.40A 3retA-1wyeA:
undetectable
3retB-1wyeA:
undetectable		 3retA-1wyeA:
18.29
3retB-1wyeA:
18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUE_D_SUED1201_2
(NS3 PROTEASE, NS4A
PROTEIN)		 1wye 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Sulfurisphaera
tokodaii) 		3 / 3 TYR A 107
LEU A 116
LYS A 115
 None
 0.70A 3sueD-1wyeA:
undetectable		 3sueD-1wyeA:
19.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UBO_A_ADNA353_1
(ADENOSINE KINASE)		 1wye 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Sulfurisphaera
tokodaii) 		6 / 12 GLY A  34
SER A  35
ASN A  38
GLU A  36
GLY A 253
ASP A 256
 None
 0.86A 3uboA-1wyeA:
36.6		 3uboA-1wyeA:
25.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UBO_B_ADNB353_1
(ADENOSINE KINASE)		 1wye 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Sulfurisphaera
tokodaii) 		5 / 12 GLY A  34
ASN A  38
GLU A  36
THR A 252
ASP A 256
 None
 0.97A 3uboB-1wyeA:
37.3		 3uboB-1wyeA:
25.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCJ_A_AZMA229_1
(CARBONIC ANHYDRASE)		 1wye 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Sulfurisphaera
tokodaii) 		5 / 10 ASP A 250
VAL A 287
GLY A 253
ALA A 254
ALA A 257
 None
 1.23A 3ucjA-1wyeA:
undetectable		 3ucjA-1wyeA:
23.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCJ_B_AZMB229_2
(CARBONIC ANHYDRASE)		 1wye 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Sulfurisphaera
tokodaii) 		5 / 10 ASP A 250
VAL A 287
GLY A 253
ALA A 254
ALA A 257
 None
 1.22A 3ucjB-1wyeA:
undetectable		 3ucjB-1wyeA:
23.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAQ_A_ADNA401_1
(PUTATIVE ADENOSINE
KINASE)		 1wye 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Sulfurisphaera
tokodaii) 		5 / 12 LEU A 169
GLY A  34
ASN A  38
GLY A 253
ASP A 256
 None
 1.04A 3vaqA-1wyeA:
31.8		 3vaqA-1wyeA:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAQ_B_ADNB401_1
(PUTATIVE ADENOSINE
KINASE)		 1wye 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Sulfurisphaera
tokodaii) 		5 / 12 LEU A 169
GLY A  34
ASN A  38
GLY A 253
ASP A 256
 None
 1.04A 3vaqB-1wyeA:
30.6		 3vaqB-1wyeA:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAS_B_ADNB401_1
(PUTATIVE ADENOSINE
KINASE)		 1wye 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Sulfurisphaera
tokodaii) 		5 / 12 LEU A 169
GLY A  34
ASN A  38
GLY A 253
ASP A 256
 None
 1.01A 3vasB-1wyeA:
21.5		 3vasB-1wyeA:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3A_A_ADNA500_1
(SUGAR KINASE PROTEIN)		 1wye 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Sulfurisphaera
tokodaii) 		5 / 12 GLY A  34
ASN A  38
GLU A  36
THR A 252
ASP A 256
 None
 0.90A 4e3aA-1wyeA:
37.1		 4e3aA-1wyeA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3A_B_ADNB500_1
(SUGAR KINASE PROTEIN)		 1wye 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Sulfurisphaera
tokodaii) 		6 / 12 GLY A  34
ASN A  38
GLU A  36
THR A 252
GLY A 253
ASP A 256
 None
 0.86A 4e3aB-1wyeA:
37.1		 4e3aB-1wyeA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EMA_A_BRLA601_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1wye 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Sulfurisphaera
tokodaii) 		3 / 3 PHE A 270
VAL A 222
ILE A 220
 None
 0.62A 4emaA-1wyeA:
undetectable		 4emaA-1wyeA:
25.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKS_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 1wye 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Sulfurisphaera
tokodaii) 		5 / 12 GLY A  34
ASN A  38
GLU A  36
THR A 252
ASP A 256
 None
 0.92A 4jksA-1wyeA:
37.3		 4jksA-1wyeA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKS_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 1wye 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Sulfurisphaera
tokodaii) 		5 / 12 GLY A  34
ASN A  38
GLU A  36
THR A 252
ASP A 256
 None
 0.90A 4jksB-1wyeA:
37.2		 4jksB-1wyeA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKU_A_ADNA500_1
(PROBABLE SUGAR
KINASE PROTEIN)		 1wye 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Sulfurisphaera
tokodaii) 		5 / 12 GLY A  34
ASN A  38
GLU A  36
THR A 252
ASP A 256
 None
 0.92A 4jkuA-1wyeA:
37.1		 4jkuA-1wyeA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKU_B_ADNB500_1
(PROBABLE SUGAR
KINASE PROTEIN)		 1wye 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Sulfurisphaera
tokodaii) 		5 / 12 GLY A  34
ASN A  38
GLU A  36
THR A 252
ASP A 256
 None
 0.92A 4jkuB-1wyeA:
37.2		 4jkuB-1wyeA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8C_A_ADNA401_1
(SUGAR KINASE)		 1wye 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Sulfurisphaera
tokodaii) 		5 / 12 GLY A  34
ASN A  38
GLU A  36
THR A 252
ASP A 256
 None
 0.92A 4k8cA-1wyeA:
37.3		 4k8cA-1wyeA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8C_B_ADNB401_1
(SUGAR KINASE)		 1wye 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Sulfurisphaera
tokodaii) 		5 / 12 GLY A  34
ASN A  38
GLU A  36
THR A 252
ASP A 256
 None
 0.91A 4k8cB-1wyeA:
37.3		 4k8cB-1wyeA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8K_A_ADNA401_1
(SUGAR KINASE)		 1wye 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Sulfurisphaera
tokodaii) 		5 / 12 GLY A  34
ASN A  38
GLU A  36
THR A 252
ASP A 256
 None
 0.92A 4k8kA-1wyeA:
37.2		 4k8kA-1wyeA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8K_B_ADNB403_1
(SUGAR KINASE)		 1wye 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Sulfurisphaera
tokodaii) 		5 / 12 GLY A  34
ASN A  38
GLU A  36
THR A 252
ASP A 256
 None
 0.92A 4k8kB-1wyeA:
37.2		 4k8kB-1wyeA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8P_A_ADNA401_1
(SUGAR KINASE)		 1wye 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Sulfurisphaera
tokodaii) 		5 / 12 GLY A  34
ASN A  38
GLU A  36
THR A 252
ASP A 256
 None
 0.90A 4k8pA-1wyeA:
37.3		 4k8pA-1wyeA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8P_B_ADNB401_1
(SUGAR KINASE)		 1wye 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Sulfurisphaera
tokodaii) 		5 / 12 GLY A  34
ASN A  38
GLU A  36
THR A 252
ASP A 256
 None
 0.90A 4k8pB-1wyeA:
37.1		 4k8pB-1wyeA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8T_A_ADNA401_1
(SUGAR KINASE)		 1wye 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Sulfurisphaera
tokodaii) 		5 / 12 GLY A  34
ASN A  38
GLU A  36
THR A 252
ASP A 256
 None
 0.91A 4k8tA-1wyeA:
37.2		 4k8tA-1wyeA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8T_B_ADNB401_1
(SUGAR KINASE)		 1wye 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Sulfurisphaera
tokodaii) 		5 / 12 GLY A  34
ASN A  38
GLU A  36
THR A 252
ASP A 256
 None
 0.90A 4k8tB-1wyeA:
37.1		 4k8tB-1wyeA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K93_A_ADNA401_1
(SUGAR KINASE)		 1wye 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Sulfurisphaera
tokodaii) 		5 / 12 GLY A  34
ASN A  38
GLU A  36
THR A 252
ASP A 256
 None
 0.91A 4k93A-1wyeA:
37.2		 4k93A-1wyeA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K93_B_ADNB402_1
(SUGAR KINASE)		 1wye 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Sulfurisphaera
tokodaii) 		5 / 12 GLY A  34
ASN A  38
GLU A  36
THR A 252
ASP A 256
 None
 0.91A 4k93B-1wyeA:
37.3		 4k93B-1wyeA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K9C_A_ADNA401_1
(SUGAR KINASE)		 1wye 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Sulfurisphaera
tokodaii) 		5 / 12 GLY A  34
ASN A  38
GLU A  36
THR A 252
ASP A 256
 None
 0.91A 4k9cA-1wyeA:
37.2		 4k9cA-1wyeA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K9C_B_ADNB401_1
(SUGAR KINASE)		 1wye 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Sulfurisphaera
tokodaii) 		5 / 12 GLY A  34
ASN A  38
GLU A  36
THR A 252
ASP A 256
 None
 0.89A 4k9cB-1wyeA:
37.2		 4k9cB-1wyeA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K9I_A_ADNA401_1
(SUGAR KINASE)		 1wye 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Sulfurisphaera
tokodaii) 		5 / 12 GLY A  34
ASN A  38
GLU A  36
THR A 252
ASP A 256
 None
 0.91A 4k9iA-1wyeA:
37.2		 4k9iA-1wyeA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K9I_B_ADNB401_1
(SUGAR KINASE)		 1wye 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Sulfurisphaera
tokodaii) 		5 / 12 GLY A  34
ASN A  38
GLU A  36
THR A 252
ASP A 256
 None
 0.92A 4k9iB-1wyeA:
37.2		 4k9iB-1wyeA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAD_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 1wye 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Sulfurisphaera
tokodaii) 		5 / 12 GLY A  34
ASN A  38
GLU A  36
THR A 252
ASP A 256
 None
 0.94A 4kadA-1wyeA:
37.3		 4kadA-1wyeA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAD_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 1wye 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Sulfurisphaera
tokodaii) 		5 / 12 GLY A  34
ASN A  38
GLU A  36
THR A 252
ASP A 256
 None
 0.92A 4kadB-1wyeA:
37.2		 4kadB-1wyeA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAH_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 1wye 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Sulfurisphaera
tokodaii) 		5 / 12 GLY A  34
ASN A  38
GLU A  36
THR A 252
ASP A 256
 None
 0.90A 4kahA-1wyeA:
37.2		 4kahA-1wyeA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAH_B_ADNB502_1
(PROBABLE SUGAR
KINASE PROTEIN)		 1wye 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Sulfurisphaera
tokodaii) 		5 / 12 GLY A  34
ASN A  38
GLU A  36
THR A 252
ASP A 256
 None
 0.91A 4kahB-1wyeA:
37.3		 4kahB-1wyeA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAL_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 1wye 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Sulfurisphaera
tokodaii) 		5 / 12 GLY A  34
ASN A  38
GLU A  36
THR A 252
ASP A 256
 None
 0.90A 4kalA-1wyeA:
37.2		 4kalA-1wyeA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAL_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 1wye 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Sulfurisphaera
tokodaii) 		5 / 12 GLY A  34
ASN A  38
GLU A  36
THR A 252
ASP A 256
 None
 0.91A 4kalB-1wyeA:
37.1		 4kalB-1wyeA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAN_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 1wye 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Sulfurisphaera
tokodaii) 		5 / 12 GLY A  34
ASN A  38
GLU A  36
THR A 252
ASP A 256
 None
 0.91A 4kanA-1wyeA:
37.2		 4kanA-1wyeA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAN_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 1wye 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Sulfurisphaera
tokodaii) 		5 / 12 GLY A  34
ASN A  38
GLU A  36
THR A 252
ASP A 256
 None
 0.91A 4kanB-1wyeA:
37.2		 4kanB-1wyeA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KBE_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 1wye 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Sulfurisphaera
tokodaii) 		5 / 12 GLY A  34
ASN A  38
GLU A  36
THR A 252
ASP A 256
 None
 0.90A 4kbeA-1wyeA:
37.1		 4kbeA-1wyeA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KBE_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 1wye 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Sulfurisphaera
tokodaii) 		5 / 12 GLY A  34
ASN A  38
GLU A  36
THR A 252
ASP A 256
 None
 0.90A 4kbeB-1wyeA:
37.2		 4kbeB-1wyeA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 1wye 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Sulfurisphaera
tokodaii) 		5 / 12 GLY A  34
ASN A  38
GLU A  36
THR A 252
ASP A 256
 None
 0.92A 4lbgA-1wyeA:
37.2		 4lbgA-1wyeA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 1wye 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Sulfurisphaera
tokodaii) 		5 / 12 GLY A  34
ASN A  38
GLU A  36
THR A 252
ASP A 256
 None
 0.92A 4lbgB-1wyeA:
37.2		 4lbgB-1wyeA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBX_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 1wye 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Sulfurisphaera
tokodaii) 		5 / 12 GLY A  34
ASN A  38
GLU A  36
THR A 252
ASP A 256
 None
 0.92A 4lbxA-1wyeA:
37.2		 4lbxA-1wyeA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBX_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 1wye 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Sulfurisphaera
tokodaii) 		5 / 12 GLY A  34
ASN A  38
GLU A  36
THR A 252
ASP A 256
 None
 0.91A 4lbxB-1wyeA:
37.3		 4lbxB-1wyeA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LC4_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 1wye 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Sulfurisphaera
tokodaii) 		5 / 12 GLY A  34
ASN A  38
GLU A  36
THR A 252
ASP A 256
 None
 0.92A 4lc4A-1wyeA:
37.2		 4lc4A-1wyeA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LC4_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 1wye 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Sulfurisphaera
tokodaii) 		5 / 12 GLY A  34
ASN A  38
GLU A  36
THR A 252
ASP A 256
 None
 0.90A 4lc4B-1wyeA:
37.2		 4lc4B-1wyeA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LCA_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 1wye 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Sulfurisphaera
tokodaii) 		5 / 12 GLY A  34
ASN A  38
GLU A  36
THR A 252
ASP A 256
 None
 0.92A 4lcaA-1wyeA:
37.3		 4lcaA-1wyeA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LCA_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 1wye 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Sulfurisphaera
tokodaii) 		5 / 12 GLY A  34
ASN A  38
GLU A  36
THR A 252
ASP A 256
 None
 0.90A 4lcaB-1wyeA:
37.2		 4lcaB-1wyeA:
23.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_A_ADNA401_1
(ADENOSINE KINASE)		 1wye 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Sulfurisphaera
tokodaii) 		5 / 12 LEU A 169
GLY A  34
ASN A  38
GLY A 253
ASP A 256
 None
 1.16A 4n09A-1wyeA:
31.2		 4n09A-1wyeA:
24.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_A_ADNA401_1
(ADENOSINE KINASE)		 1wye 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Sulfurisphaera
tokodaii) 		5 / 12 LEU A 169
GLY A  34
ASN A  38
GLY A 255
ASP A 256
 None
 1.22A 4n09A-1wyeA:
31.2		 4n09A-1wyeA:
24.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RP8_C_ASCC501_1
(ASCORBATE-SPECIFIC
PERMEASE IIC
COMPONENT ULAA)		 1wye 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Sulfurisphaera
tokodaii) 		3 / 3 SER A 104
TYR A 106
ASP A 292
 None
 0.73A 4rp8C-1wyeA:
2.1		 4rp8C-1wyeA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z69_A_DIFA1006_1
(SERUM ALBUMIN)		 1wye 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Sulfurisphaera
tokodaii) 		4 / 7 ILE A 280
LEU A 258
GLY A 226
LYS A 228
 None
 1.04A 4z69A-1wyeA:
undetectable		 4z69A-1wyeA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZXI_A_GLYA1402_0
(TYROCIDINE
SYNTHETASE 3)		 1wye 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Sulfurisphaera
tokodaii) 		4 / 7 ASP A 197
ILE A 165
GLY A 136
THR A 193
 None
 0.91A 4zxiA-1wyeA:
2.3		 4zxiA-1wyeA:
13.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HWA_A_GCSA303_1
(CHITOSANASE)		 1wye 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Sulfurisphaera
tokodaii) 		4 / 5 ASP A 194
VAL A 251
GLY A 255
ALA A 254
 None
 1.02A 5hwaA-1wyeA:
undetectable		 5hwaA-1wyeA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JKW_A_TESA601_1
(AROMATASE)		 1wye 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Sulfurisphaera
tokodaii) 		5 / 11 ILE A 179
ILE A 165
ASP A 197
THR A 193
LEU A 202
 None
 1.24A 5jkwA-1wyeA:
undetectable		 5jkwA-1wyeA:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JL6_A_ASDA601_1
(AROMATASE)		 1wye 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Sulfurisphaera
tokodaii) 		5 / 9 ILE A 179
ILE A 165
ASP A 197
THR A 193
LEU A 202
 None
 1.24A 5jl6A-1wyeA:
0.0		 5jl6A-1wyeA:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JL7_A_ASDA601_1
(AROMATASE)		 1wye 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Sulfurisphaera
tokodaii) 		5 / 10 ILE A 179
ILE A 165
ASP A 197
THR A 193
LEU A 202
 None
 1.23A 5jl7A-1wyeA:
0.0		 5jl7A-1wyeA:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JL9_A_ASDA601_1
(AROMATASE)		 1wye 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Sulfurisphaera
tokodaii) 		5 / 9 ILE A 179
ILE A 165
ASP A 197
THR A 193
LEU A 202
 None
 1.25A 5jl9A-1wyeA:
0.0		 5jl9A-1wyeA:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SYE_B_TA1B502_1
(TUBULIN BETA CHAIN)		 1wye 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Sulfurisphaera
tokodaii) 		5 / 12 GLU A 119
ASP A 120
LEU A 182
ALA A 152
GLY A   8
 None
 1.09A 5syeB-1wyeA:
5.4		 5syeB-1wyeA:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SYE_B_TA1B502_1
(TUBULIN BETA CHAIN)		 1wye 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Sulfurisphaera
tokodaii) 		5 / 12 VAL A 121
ASP A 120
LEU A 182
ALA A 152
GLY A   8
 None
 1.10A 5syeB-1wyeA:
5.4		 5syeB-1wyeA:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VEU_B_RITB602_1
(CYTOCHROME P450 3A5)		 1wye 2-KETO-3-DEOXYGLUCON
ATE KINASE
(Sulfurisphaera
tokodaii) 		5 / 12 LEU A 306
PHE A 270
ILE A 302
ALA A 230
ILE A 231
 None
 1.05A 5veuB-1wyeA:
undetectable		 5veuB-1wyeA:
23.92