SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1wym'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EII_A_RTLA135_0
(CELLULAR
RETINOL-BINDING
PROTEIN II)		 1wym TRANSGELIN-2
(Homo
sapiens) 		5 / 12 ALA A 130
ILE A 102
THR A 120
LEU A 121
LEU A  61
 None
 1.35A 1eiiA-1wymA:
undetectable		 1eiiA-1wymA:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9P_C_DESC500_1
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 1wym TRANSGELIN-2
(Homo
sapiens) 		5 / 12 LEU A 121
LEU A 124
LEU A 127
ALA A 128
ILE A  26
 None
 1.02A 1s9pC-1wymA:
undetectable		 1s9pC-1wymA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HB6_A_DXCA75_0
(PPCA)		 1wym TRANSGELIN-2
(Homo
sapiens) 		4 / 8 ILE A  58
LEU A  61
ILE A  26
GLY A 126
 None
 0.88A 4hb6A-1wymA:
undetectable		 4hb6A-1wymA:
17.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HB8_A_DXCA75_0
(PPCA)		 1wym TRANSGELIN-2
(Homo
sapiens) 		4 / 8 ILE A  58
LEU A  61
ILE A  26
GLY A 126
 None
 0.71A 4hb8A-1wymA:
undetectable		 4hb8A-1wymA:
17.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIW_A_OAQA302_0
(SULFOTRANSFERASE)		 1wym TRANSGELIN-2
(Homo
sapiens) 		5 / 12 ILE A  85
ILE A 102
LEU A 108
LEU A 121
THR A 120
 None
 1.09A 5tiwA-1wymA:
undetectable		 5tiwA-1wymA:
21.48