SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '1wyp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DEU_A_SALA305_1
(TRANSCRIPTIONAL
REGULATOR SLYA)		 1wyp CALPONIN 1
(Homo
sapiens) 		5 / 7 VAL A  88
THR A  84
ILE A  83
ILE A  52
SER A  59
 None
 1.31A 3deuA-1wypA:
undetectable		 3deuA-1wypA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LP9_D_SPMD230_1
(LS-24)		 1wyp CALPONIN 1
(Homo
sapiens) 		3 / 3 GLU A  65
GLU A  74
ASN A  75
 None
 0.44A 3lp9B-1wypA:
undetectable
3lp9D-1wypA:
undetectable		 3lp9B-1wypA:
21.59
3lp9D-1wypA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W67_C_VIVC301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 1wyp CALPONIN 1
(Homo
sapiens) 		5 / 12 ILE A  76
VAL A 108
LEU A 113
PHE A  79
ILE A  26
 None
 0.97A 3w67C-1wypA:
undetectable		 3w67C-1wypA:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W68_B_VIVB301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 1wyp CALPONIN 1
(Homo
sapiens) 		5 / 12 ILE A  76
VAL A 108
LEU A 113
PHE A  79
ILE A  26
 None
 1.02A 3w68B-1wypA:
undetectable		 3w68B-1wypA:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YW0_A_ACTA412_0
(UNCHARACTERIZED
PROTEIN KDOO)		 1wyp CALPONIN 1
(Homo
sapiens) 		3 / 3 LYS A   9
ASN A   8
SER A   5
 None
 1.27A 5yw0A-1wypA:
undetectable		 5yw0A-1wypA:
17.74